Small Cell Lung Cancer News and Research

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Small cell lung cancer is a disease in which malignant (cancer) cells form in the tissues of the lung. Small cell lung cancer is an aggressive (fast-growing) cancer that can spread to other parts of the body. The cancer cells look small and oval-shaped when looked at under a microscope.

Alternate cell growth pathway could open door to new treatments for metastatic cancers

While researchers have a basic understanding of how primary cancer cells grow, less is known about metastasis, the deadly process by which cancers spread.

12 Jul 2019

Adding immunotherapy after initial treatment improves survival in metastatic NSCLC patients

Treating metastatic non-small cell lung cancer patients with the immunotherapy drug pembrolizumab after they've completed locally ablative therapy – meaning all known sites of their cancer were either treated with surgery, radiation, or other definitive treatments – almost tripled the median progression-free survival compared to the historical average.

12 Jul 2019

Immune system could be blamed for ineffectiveness of high-dose radiation against lung cancer

When it comes to using radiation against lung cancer, preliminary clinical studies were pretty clear: More is better.

27 Jun 2019

Three beagles successfully identify lung cancer by scent, shows study

Three beagles successfully showed they are capable of identifying lung cancer by scent, a first step in identifying specific biomarkers for the disease.

18 Jun 2019

Radiation associated with increased risk of adverse cardiac events in lung cancer patients

As advances in the treatment of non-small cell lung cancer (NSCLC) extend patients' lives, more of these patients are facing a different threat: adverse cardiovascular events, such as heart attacks and heart failure.

11 Jun 2019

Roche Diagnostics launches first in vitro diagnostic ROS1 immunohistochemistry assay

Roche Diagnostics today announced the launch of the VENTANA ROS1 Antibody, the first and only in vitro diagnostic ROS1 immunohistochemistry assay. The test detects the presence of ROS1 protein in tissue, and may be useful in identifying ROS1-positive lung cancer cases.

From Roche Sequencing and Life Science 10 Jun 2019

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Neoadjuvant, or pre-surgical, treatment with nivolumab plus ipilimumab resulted in an overall major pathologic response rate of 33 percent of treated patients with early-stage, resectable non-small cell lung cancers, meaning these patients had less than or equal to 10 percent viable tumor remaining at surgery.

3 Jun 2019

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

In a study led by UCLA investigators, treatment with the immunotherapy drug pembrolizumab helped more than 15% of people with advanced non-small cell lung cancer live for at least five years - and 25% of patients whose tumor cells had a specific protein lived at least that long.

3 Jun 2019

NCCN and AstraZeneca collaborate to improve care processes for lung cancer patients

The National Comprehensive Cancer Network Oncology Research Program and AstraZeneca, a global, science-led biopharmaceutical company, are collaborating to seek proposals for improving care processes for patients with unresectable stage III and stage IV non-small cell lung cancer.

31 May 2019

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

For patients with operable non-small cell lung cancer, pre-surgical "neoadjuvant" treatment with an immune checkpoint inhibitor was well tolerated and, in many cases, caused significant tumor cell death in a large, multicenter clinical trial involving investigators at Dana-Farber Cancer Institute, Brigham and Women's Hospital, and nine other research centers

31 May 2019

Research uncovers potential breakthrough in the understanding of tumor dormancy

Scientists at VCU Massey Cancer Center may have uncovered a primary method through which cancer cells exist undetected in an organism and received more than $1 million to investigate the potential for novel therapeutics that target and destroy cells in a specific state of tumor dormancy.

22 May 2019

Non-smokers who develop lung cancer are hugely disadvantaged, says PHE

Patients who do not smoke are at an increased risk of lung cancer due to air pollution, warns PHE. These patients are often overlooked and diagnosed late, with poor outcomes.

26 Apr 2019

Predicting whether a patient will benefit from chemotherapy

Case Western Reserve University researchers and partners, including a collaborator at Cleveland Clinic, are pushing the boundaries of how "smart" diagnostic-imaging machines identify cancers--and uncovering clues outside the tumor to tell whether a patient will respond well to chemotherapy.

25 Apr 2019

Small Cell Lung Cancer News and Research

Alternate cell growth pathway could open door to new treatments for metastatic cancers

Adding immunotherapy after initial treatment improves survival in metastatic NSCLC patients

Immune system could be blamed for ineffectiveness of high-dose radiation against lung cancer

Three beagles successfully identify lung cancer by scent, shows study

Radiation associated with increased risk of adverse cardiac events in lung cancer patients

Roche Diagnostics launches first in vitro diagnostic ROS1 immunohistochemistry assay

Combination immunotherapy shows promise in pre-surgical setting for early-stage lung cancers

Immunotherapy increases five-year survival rate of patients with advanced non-small cell lung cancer

NCCN and AstraZeneca collaborate to improve care processes for lung cancer patients

Pre-surgical neoadjuvant treatment shows promise in trial for patients with operable NSCLC

Research uncovers potential breakthrough in the understanding of tumor dormancy

Non-smokers who develop lung cancer are hugely disadvantaged, says PHE

Predicting whether a patient will benefit from chemotherapy

Researchers engineer new molecules to help stop lung cancer

Deep-learning model better predicts survival outcomes for lung cancer

Single-cell sequencing sheds light on landscape of myeloid cells in lung tumors

Study finds disparities in lung cancer treatments among Asian communities

High-dose standard radiation treatment well-tolerated by patients with centrally located NSCLC

New combination therapy found to be well tolerated in patients with aggressive brain tumor

IASLC 2019 Small Cell Lung Cancer Meeting focuses on immunotherapy and patient perspective

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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