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Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

Researchers discuss the role of a surfactant-mediated inflammatory response employed by human lungs against SARS-CoV-2.

3 Feb 2023

The relationship between natural plant extracts and SARS-CoV-2

Researchers explored plants as an extensive resource of molecules with potential therapeutic action against SARS-CoV-2 and debunked misconceptions.

3 Feb 2023

Improving CAR-based-immunotherapies using a molecular anchor

Adding a molecular anchor to the key protein used to recognize cancer in cellular immunotherapies can make the treatments significantly more effective.

3 Feb 2023

Research reveals a candidate drug and biomarker to target uveal melanoma

Findings from an international research study involving Irish and Spanish patients reveal a candidate drug and biomarker that could be used to manage uveal melanoma.

2 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Researchers evaluated the clinical and genetic characteristics of acute myeloid leukemia (AML) patients with a mutant Ikaros zinc finger protein 1 (IKZF1).

2 Feb 2023

Immunomodulatory antibodies found to be successful in treating cancer when they have a looser grip

New research from the Centre for Cancer Immunology at the University of Southampton, published ahead of World Cancer Day (4 February), has shown that changing how tightly an antibody binds to a target could improve treatments for cancer.

1 Feb 2023

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

The Mays Cancer Center, home to UT Health San Antonio MD Anderson Cancer Center, was the lead site for a study evaluating Phase I and Phase III clinical trials for elacestrant, a treatment for postmenopausal women and adult men with ER+/HER2- advanced or metastatic breast cancer.

1 Feb 2023

New optogenetic tool to study and modulate plasticity in the cerebellum

Light can trigger a signaling cascade in the cerebellum. This also illuminates processes that play an important role in cerebellar diseases.

1 Feb 2023

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

A recent study posted on the bioRxiv* preprint server has longitudinally characterized the MBC repertoire and humoral response after Omicron BA.1 breakthrough infection in individuals vaccinated with the COVID-19 mRNA vaccine.

1 Feb 2023

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

A new study looked at the whole spectrum of immunological reactions raised by spike and non-spike antigens following Omicron BA.1/BA.2 infections in such individuals, both with and without prior SARS-CoV-2 infection.

1 Feb 2023

A machine-learning approach to identify asthma subtypes based on molecular signatures

Researchers determine whether protein expression in nasal fluid samples could assist in the diagnosis of severe asthma subtypes.

31 Jan 2023

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Researchers investigated the CAMCI strategy as an immunotherapeutic option for inflammatory bowel disease.

31 Jan 2023

Rapid engineering of novel SARS-CoV-2 therapeutic antibodies

Researchers assessed the influence of rapid engineering of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) therapeutic antibodies to expand the neutralization spectrum.

31 Jan 2023

The impact of common viral infections on blood-brain barrier function and insulin sensitivity

A new study discusses the impact of several human viruses on blood-brain barrier function and insulin sensitivity.

31 Jan 2023

Structure and function of the first FDA-approved treatment for Ebola virus discovered

Scientists at La Jolla Institute for Immunology (LJI) have uncovered the structure and function of the first FDA-approved treatment for Zaire ebolavirus (Ebola virus).

30 Jan 2023

MINOCA: Insights into a type of heart attack that predominantly affects women

Heart disease is the leading cause of death among women in the U.S., and a type of heart attack called myocardial infarction with non-obstructive coronary arteries (MINOCA), which predominantly affects women, is garnering increased attention.

30 Jan 2023

Researchers discover mechanism underlying the development and intensification of cancer treatment-related pain

A combination of chemotherapy and drugs that stimulate the immune system to combat cancer is increasingly used to control progression of the disease in patients.

30 Jan 2023

New candidate molecule could become an effective non-hormonal male contraceptive

Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize an egg, yet these may not work for everyone.

30 Jan 2023

Direct stochastic optical reconstruction microscopy combined with different labeling approaches for the visualization and quantification of ACE2 on different cells

Researchers performed dSTORM (direct stochastic optical reconstruction microscopy) with several labeling techniques for visualizing and quantifying ACE2 receptor expression on various cells.

30 Jan 2023

Receptor News and Research

Pulmonary surfactant-mediated inflammatory response against SARS-CoV-2

The relationship between natural plant extracts and SARS-CoV-2

Improving CAR-based-immunotherapies using a molecular anchor

Research reveals a candidate drug and biomarker to target uveal melanoma

Researchers report a heterologous vaccination strategy against IBV in Chickens

Characterization of Ikaros zinc finger protein 1 mutations in acute myeloid leukemia

Immunomodulatory antibodies found to be successful in treating cancer when they have a looser grip

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

New optogenetic tool to study and modulate plasticity in the cerebellum

New study suggests Omicron BA.1 breakthrough infection drives long-term remodeling of memory B cell repertoire in vaccinated populations

Breakthrough Omicron BA.1/BA.2 infections in the triple-vaccinated linked to broad-based immunity

A machine-learning approach to identify asthma subtypes based on molecular signatures

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Rapid engineering of novel SARS-CoV-2 therapeutic antibodies

The impact of common viral infections on blood-brain barrier function and insulin sensitivity

Structure and function of the first FDA-approved treatment for Ebola virus discovered

MINOCA: Insights into a type of heart attack that predominantly affects women

Researchers discover mechanism underlying the development and intensification of cancer treatment-related pain

New candidate molecule could become an effective non-hormonal male contraceptive

Direct stochastic optical reconstruction microscopy combined with different labeling approaches for the visualization and quantification of ACE2 on different cells

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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