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Drug delivery breakthrough for Alzheimer’s disease

Till date all attempts to get drugs into the brain were countered by the blood-brain barrier - the natural defense against potentially harmful chemicals floating around the body. However this new finding from a team from University of Oxford shows that now scientists have successfully switched off a gene implicated in Alzheimer’s disease in the brains of mice by exploiting tiny particles naturally released by cells, called exosomes.

21 Mar 2011

African delegates call on countries to do more to prevent mother-to-child transmission of HIV

Delegates from 15 African countries this week concluded a three-day workshop held in Nairobi, Kenya, examining how countries can improve their efforts to prevent mother-to-child transmission of HIV, VOA News reports.

19 Mar 2011

Scientists devise new strategy to prevent spread of drug-resistant bacteria

A team of scientists from the University of Oxford, U.K. have taken lessons from Adam Smith and Charles Darwin to devise a new strategy that could one day slow, possibly even prevent, the spread of drug-resistant bacteria. In a new research report published in the March 2011 issue of GENETICS, the scientists show that bacterial gene mutations that lead to drug resistance come at a biological cost not borne by nonresistant strains.

19 Mar 2011

Research roundup: Successful medical homes; shortage of HIV doctors; boosting use of $4 generic drugs

Every Friday, Jennifer Evans compiles this selection of recently-released health policy studies and briefs.

19 Mar 2011

Deaths from heart attacks drop precipitously in Norway, reports NTNU researcher

Life was hard in occupied Norway during WWII, but the occupation had one surprising result: deaths from heart attacks dropped precipitously, because Norwegians ate less fat, smoked less and were more physically active.

19 Mar 2011

Journal of Clinical Lipidology publishes LipoScience LDL particle study results against CVD

LipoScience, Inc., a highly innovative diagnostic company that is advancing patient care by developing high value proprietary blood tests using nuclear magnetic resonance technology, today announced publication of a clinical study in the Journal of Clinical Lipidology demonstrating that in many people, low density lipoprotein cholesterol is a less accurate predictor of cardiovascular disease events than LDL particle number.

19 Mar 2011

Roundup: Texas attacks health law as Calif., Ind. hospitals cope with law's effects

At today's meeting of the House Select Committee on State Sovereignty, Republican lawmakers laid out a dozen bills — and a handful of different strategies — to prevent implementation of the Patient Protection and Affordable Care Act in Texas, and allow the state to operate Medicaid its own way.

19 Mar 2011

Scientists discover enzyme family that plays a crucial role in regulating cell motility

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that members of an enzyme family found in humans and throughout the plant and animal kingdoms play a crucial role in regulating cell motility. Their findings suggest an entirely new strategy for treating conditions ranging from diabetic ulcers to metastatic cancer.

19 Mar 2011

Researchers discover process that regulates DNA maintenance

DNA contains all of the genetic instructions that make us who we are, and maintaining the integrity of our DNA over the course of a lifetime is a critical, yet complex part of the aging process.

19 Mar 2011

Tocopherol derivatives as new dioxin receptor antagonists

When reactive oxygen species (ROS) hit the body, vitamin E helps to prevent damage to tissues and cells by acting as an antioxidant. The health benefits of vitamin E are numerous, and in fact, studies have found that people with higher levels of vitamin E in their system have a lower risk of heart disease and certain forms of cancer. A team led by Thomas Rosenau from the University of Natural Resources and Life Sciences in Vienna (Austria) now describe their synthesis of a series of modified vitamin E derivatives that show promise as dioxin receptor antagonists in the European Journal of Organic Chemistry.

18 Mar 2011

Sage Bionetworks, AstraZeneca enter cancer research collaboration

Sage Bionetworks and AstraZeneca have initiated a collaboration to make new insights into certain cancers using advanced computational models of disease genetics. This deeper understanding of cancer will potentially help better match patients with appropriate treatments and might one day lead to new cancer therapeutics.

18 Mar 2011

Medical Facilities fourth quarter consolidated facility service revenue increases 10.9% to $64.4 million

Medical Facilities Corporation, today reported its financial results for the three- and twelve-month periods ended December 31, 2010.

18 Mar 2011

Researchers discover a type of 'cellular bilingualism' in brain

A team of researchers from the University of Montreal and McGill University have discovered a type of "cellular bilingualism" - a phenomenon that allows a single neuron to use two different methods of communication to exchange information.

18 Mar 2011

Medicare officials signal no payment changes on anemia drugs

Medicare officials signaled Wednesday that they will not change a payment policy for biotech drugs made by Amgen and Johnson & Johnson when they are used to treat anemia in kidney disease patients, despite data suggesting heart risks for those patients.

18 Mar 2011

Science journal publishes CYTK preclinical cardiac myosin activation research results

Cytokinetics, Incorporated announced today the publication of preclinical research in the March 18, 2011 issue of the journal Science regarding the activation of cardiac myosin by an investigational drug candidate, omecamtiv mecarbil, and the potential therapeutic role that this novel mechanism may play for patients with systolic heart failure.

18 Mar 2011

Modified mRNA raises hope for safe and effective cancer drugs

Modern gene therapies raise hopes of combating many diseases until now considered terminal. Nowadays, however, the methods are expensive and carry a risk of severe complications.

18 Mar 2011

Vitamin A may play key role in sperm cell formation and development of central nervous system

In a recently-published study mapping the structure and function of the so-called "orphan" nuclear receptor TR4, Van Andel Research Institute (VARI) investigators suggest that Vitamin A may play a more direct role than was previously known in certain physiological functions including sperm cell formation and the development of the central nervous system.

18 Mar 2011

Study: Daily hemodialysis can help alleviate sleep problems related to RLS

For dialysis patients, performing daily dialysis at home can help alleviate sleep problems related to restless legs syndrome, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

18 Mar 2011

Scientists receive £5million EU grant to identify gene targets for kidney cancer treatment

An international consortium led by scientists from the Cancer Research UK London Research Institute, The Royal Marsden Hospital and the Technical University of Denmark has been granted nearly £5million by the European Union to identify gene targets for personalised treatment for kidney cancer patients.

18 Mar 2011

Roundup: Cuts in Calif. programs; Ga. seeks federal MLR waiver; N.J. lawmakers try to restore some health funding

State lawmakers Wednesday approved billions of dollars in cuts to welfare, medical programs for the poor and in-home care for the elderly and frail, among other services, moving forward key pieces of Gov. Jerry Brown's budget reduction package.

18 Mar 2011

Drugs News and Research

Drug delivery breakthrough for Alzheimer’s disease

African delegates call on countries to do more to prevent mother-to-child transmission of HIV

Scientists devise new strategy to prevent spread of drug-resistant bacteria

Research roundup: Successful medical homes; shortage of HIV doctors; boosting use of $4 generic drugs

Deaths from heart attacks drop precipitously in Norway, reports NTNU researcher

Journal of Clinical Lipidology publishes LipoScience LDL particle study results against CVD

Roundup: Texas attacks health law as Calif., Ind. hospitals cope with law's effects

Scientists discover enzyme family that plays a crucial role in regulating cell motility

Researchers discover process that regulates DNA maintenance

Tocopherol derivatives as new dioxin receptor antagonists

Sage Bionetworks, AstraZeneca enter cancer research collaboration

Medical Facilities fourth quarter consolidated facility service revenue increases 10.9% to $64.4 million

Researchers discover a type of 'cellular bilingualism' in brain

Medicare officials signal no payment changes on anemia drugs

Science journal publishes CYTK preclinical cardiac myosin activation research results

Modified mRNA raises hope for safe and effective cancer drugs

Vitamin A may play key role in sperm cell formation and development of central nervous system

Study: Daily hemodialysis can help alleviate sleep problems related to RLS

Scientists receive £5million EU grant to identify gene targets for kidney cancer treatment

Roundup: Cuts in Calif. programs; Ga. seeks federal MLR waiver; N.J. lawmakers try to restore some health funding

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