Protein C News and Research

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Pancreatic mesenchyme plays central role in the formation of mature beta cells

A somewhat mysterious soft tissue found in the fetus during early development in the womb plays a pivotal role in the formation of mature beta cells the sole source of the body's insulin. This discovery, made by scientists at University of California, San Francisco (UCSF) and Texas A&M University, may lead to new ways of addressing Type 1 and Type 2 diabetes.

7 Sep 2011

Scientists uncover new ways to stimulate pancreatic beta cell growth

One of the holy grails in diabetes research is to discover molecules that stimulate beta cell growth and to find drugs that target these molecules. Now, JDRF-funded researchers in collaboration with the pharmaceutical company Hoffmann-La Roche, have done both, discovering not only a protein that regulates beta cell growth, but also a chemical compound that stimulates it.

7 Sep 2011

Leading cancer journals publish OncoGenex's custirsen pre-clinical and Phase II study data

OncoGenex Pharmaceuticals, Inc. announced today that data from two studies, a Phase II clinical study and a pre-clinical study, evaluating the investigational compound custirsen, were published in the September issues of the journals Clinical Cancer Research and Cancer Research.

7 Sep 2011

Researchers investigate special diets that could help youngsters keep the weight off

A shocking 17 per cent of boys and 15 per cent of girls aged two to 15 years are obese in the UK, putting them at risk of serious, long-term health problems. Now a team of Aberdeen researchers are investigating special diets which could help youngsters keep the weight off, thanks to a grant from children's charity Action Medical Research.

7 Sep 2011

Discovery of a key protein’s role in cell clearance could impact future treatments of autoimmune diseases, obesity and atherosclerosis

The healthy human body is extremely efficient at cleaning house. Every day, we purge 100 to 200 billion dead or dying cells – a process called cell clearance, which is fundamental in our ability to maintain a healthy physiological balance and prevent a number of chronic diseases. Professional cleaning cells, called phagocytes, are responsible for ridding the body of dead, or ‘apoptotic,’ cells.

6 Sep 2011

McMaster team demonstrates essential role of AMPK enzyme in exercise

You may think your lack of resolve to get off the couch to exercise is because you're lazy, but McMaster University researchers have discovered it may be you are missing key genes.

6 Sep 2011

Bruker releases new amaZon speed ion trap mass spectrometers

At the HUPO 10th Annual World Congress in Geneva, Switzerland, and at the JAIMA Conference in Tokyo, Japan, Bruker this week announces the release of its new high-performance amaZon speed and amaZon speed ETD ion trap mass spectrometers (ITMS) to meet the increasing demands of the proteomics, research and applied markets.

6 Sep 2011

Researchers discover how yeast cells identify, attach to human tissue and cause infection

Researchers are a step closer towards creating a new class of medicines and vaccines to combat drug-resistant and deadly strains of fungal infections, following a new study published today in Proceedings of the National Academy of Sciences.

6 Sep 2011

Researchers discover novel way to increase amounts of antibiotics

A novel way of increasing the amounts of antibiotics produced by bacteria has been discovered that could markedly improve the yields of these important compounds in commercial production. It could also be valuable in helping to discover new compounds. With the ever-growing threat from antibiotic resistance, these tools will be very useful in ensuring that we have enough of these useful compounds in the future.

5 Sep 2011

'Shan Song' finds new way of processing non-genetically modified soybeans

How much did you know about soybeans? How did you find the difference between GM soybeans and non-GM soybeans? How can people find the 'New Market' for traditional non-GM soybeans? You may get the answer if you knew 'Shan Song'.

5 Sep 2011

Cancer cells with specific genetic defect extra susceptible to therapy that damages DNA

Using a strategy based on treating cancer cells that carry a specific genetic signature - hyper-expression of the protein Myc - with therapy that affects the stability of the cell's DNA, more effective results can be achieved.

5 Sep 2011

Scientists purify PARP protein that shows promise against breast, ovarian cancers

CANCER RESEARCH UK scientists have succeeded in purifying a protein found in bacteria that could reveal new drug targets for inherited breast and ovarian cancers - and other cancers linked to DNA repair faults.

5 Sep 2011

Inflammation boosts activity of two proteins that can normalize blood sugar in diabetics

Increased low-grade inflammation in the body resulting from obesity is widely viewed as contributing to type 2 diabetes. Going against this long-held belief, researchers from Children's Hospital Boston report that two proteins activated by inflammation are actually crucial for maintaining good blood sugar levels - and that boosting the activity of these proteins can normalize blood sugar in severely obese and diabetic mice.

5 Sep 2011

Researchers discover group of mutations involved in T-cell acute lymphoblastic leukemia

An international team of researchers has found a group of mutations involved in T-cell acute lymphoblastic leukemia (T-ALL), and showed that a group of certain drugs, already in clinical use to treat other diseases, can eliminate the cells carrying these mutations.

5 Sep 2011

Study describes new class of anti-diabetic compound that targets unique molecular switch

In a joint study, scientists from The Scripps Research Institute and Harvard University's Dana-Farber Cancer Institute have established a new class of anti-diabetic compound that targets a unique molecular switch.

5 Sep 2011

Researchers help explain elusive mechanics of complex cell transport system

Every cell in the human body contains a complex system to transport essential cargoes such as proteins and membrane vesicles, from point A to point B. These tiny molecular motor proteins move at blistering speeds on miniature railways carrying components of the cell to their proper destinations.

3 Sep 2011

Researchers discover protein signals responsible for preserving anti-viral antibodies

Our immune system is capable of a remarkable feat: the ability to remember infections for years, even decades, after they have first been encountered and defeated. While the antibodies we make last only about a month, we retain the means of making them for a lifetime.

3 Sep 2011

Scientists discover highly conserved mechanism governing brain development

If you think today's political rhetoric is overheated, imagine what goes on inside a vertebrate embryo. There, two armies whose agendas are poles apart, engage in a battle with consequences much more dire than whether the economy will recover---- they are battling for whether you (or frogs or chickens) will have a forebrain.

3 Sep 2011

UCF, UF receive $5.5 million NIH grant for hemophilia research

At a time when research funding is hard to come by, a University of Central Florida and University of Florida partnership has landed almost $5.5 million in National Institutes of Health highly competitive grants for hemophilia research.

3 Sep 2011

Study finds link between long-term dietary patterns and human gut bacteria

"You are what you eat" is familiar enough, but how deep do the implications go? An interdisciplinary group of investigators from the Perelman School of Medicine at the University of Pennsylvania have found an association between long-term dietary patterns and the bacteria of the human gut.

3 Sep 2011

Protein C News and Research

Pancreatic mesenchyme plays central role in the formation of mature beta cells

Scientists uncover new ways to stimulate pancreatic beta cell growth

Leading cancer journals publish OncoGenex's custirsen pre-clinical and Phase II study data

Researchers investigate special diets that could help youngsters keep the weight off

Discovery of a key protein’s role in cell clearance could impact future treatments of autoimmune diseases, obesity and atherosclerosis

McMaster team demonstrates essential role of AMPK enzyme in exercise

Bruker releases new amaZon speed ion trap mass spectrometers

Researchers discover how yeast cells identify, attach to human tissue and cause infection

Researchers discover novel way to increase amounts of antibiotics

'Shan Song' finds new way of processing non-genetically modified soybeans

Cancer cells with specific genetic defect extra susceptible to therapy that damages DNA

Scientists purify PARP protein that shows promise against breast, ovarian cancers

Inflammation boosts activity of two proteins that can normalize blood sugar in diabetics

Researchers discover group of mutations involved in T-cell acute lymphoblastic leukemia

Study describes new class of anti-diabetic compound that targets unique molecular switch

Researchers help explain elusive mechanics of complex cell transport system

Researchers discover protein signals responsible for preserving anti-viral antibodies

Scientists discover highly conserved mechanism governing brain development

UCF, UF receive $5.5 million NIH grant for hemophilia research

Study finds link between long-term dietary patterns and human gut bacteria

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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