Therapy News and Research

RSS

Preliminary results from Soligenix SGX201 Phase 1/2 trial on acute radiation enteritis

Soligenix, Inc., a development stage biopharmaceutical company, announced preliminary results today from a Phase 1/2 clinical trial evaluating SGX201, a time-release formulation of oral beclomethasone 17,21-dipropionate (oral BDP), for the prevention of acute radiation enteritis.

10 Feb 2012

Hospitals seek to consolidate in Ga., Wis. and N.Y.; Other state hospital news

Hospitals in Atlanta, Wisconsin and New York are consolidating or partnering more closely with others in a bid to reduce costs and save themselves. In other hospital news, small California hospitals market back surgery to patients and a Minnesota hospital faces a "patient abuse" crisis.

10 Feb 2012

Gene therapy to promote remyelination in mouse model of MS

Our bodies are full of tiny superheroes-antibodies that fight foreign invaders, cells that regenerate, and structures that ensure our systems run smoothly. One such structure is myelin-a material that forms a protective, insulating cape around the axons of our nerve cells so that they can send signals quickly and efficiently. But myelin, and the specialized cells called oligodendrocytes that make it, become damaged in demyelinating diseases like multiple sclerosis (MS), leaving neurons without their myelin sheaths.

10 Feb 2012

IKBKE protein plays two roles in tobacco-related NSCLC

Researchers at Moffitt Cancer Center in Tampa, Fla., have discovered that the immune response regulator IKBKE (serine/threonine kinase) plays two roles in tobacco-related non-small cell lung cancers. Tobacco carcinogens induce IKBKE and, in turn, IKBKE induces chemotherapy resistance.

10 Feb 2012

PAP improves attention, anxiety and QOL in children with OSAS

Children and adolescents with obstructive sleep apnea had substantial improvements in attention, anxiety and quality of life after treatment with positive airway pressure (PAP)—a nighttime therapy in which a machine delivers a stream of air through a mask into the nose.

10 Feb 2012

University of Haifa study to shed new light on DCD

Children showing difficulty carrying out routine actions, such as getting dressed, playing with particular types of games, drawing, copying from the board in school and even typing at the computer, could be suffering from developmental coordination disorder (DCD), and not necessarily from ADHD or other more familiar disorders, points out Prof. Sara Rosenblum of the Department of Occupational Therapy at the University of Haifa, whose new study set out to shed new light on DCD.

10 Feb 2012

New cERD method can detect RNAi activity in biological fluids

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that its scientists have discovered a novel method for monitoring RNAi activity in blood samples, representing a potential major advance for future development of RNAi therapeutics, other therapeutic modalities, and diagnostics.

10 Feb 2012

Two new NCCN guidelines for patients with colon and prostrate cancer

In order to provide people with cancer and their caregivers state-of-the-art treatment information in patient-friendly language, the National Comprehensive Cancer Network (NCCN) has developed two new publications: a new release of the NCCN Guidelines for Patients: Colon Cancer and an update to the NCCN Guidelines for Patients: Prostate Cancer.

9 Feb 2012

FDA panel votes against Amgen’s Xgeva in prostate cancer

An FDA panel of oncologists has voted against a new use for Amgen's Xgeva in prostate cancer on Wednesday, saying the drug's ability to slow the spread of the disease did not translate into meaningful benefits for patients. Xgeva is already approved to prevent fractures in cancerous bones, and for osteoporosis, in a different formulation called Prolia.

9 Feb 2012

Gene therapy succeeds in the second blind eye for three patients

Three people have now have reported a dramatic improvement in vision after having gene therapy in both eyes after having lost their eyesight as children.

9 Feb 2012

Important to include men in HIV prevention, treatment programs

While a focus on HIV prevention and treatment among women and children has reduced infection rates among these populations, "men have received considerably less attention in the epidemic and receive less targeted HIV prevention and treatment programs," Edward Mills of the University of Ottawa and colleagues write in a PLoS Medicine essay, adding "Targeting men in prevention and treatment ... may have a large impact on mortality, new infections, and the economic impact of HIV/AIDS in Africa."

9 Feb 2012

Patients with GERD benefit from radiofrequency ablation

Heartburn. Acid reflux, GERD. They're different terms for the same type of condition - stomach acid used for digestion travels back up the esophagus, the "food pipe" that connects your throat to your stomach.

9 Feb 2012

Obama administration pledges $156 million for Alzheimer's research and care

Research to investigate the genetic underpinnings of the disease and to test drugs that may arrest its development will get an immediate $50 million boost.

9 Feb 2012

Readministration of gene therapy improves vision in three patients with LCA

Gene therapy for congenital blindness has taken another step forward, as researchers further improved vision in three adult patients previously treated in one eye.

9 Feb 2012

Fasting and chemotherapy drugs more effectively treat cancers

Man may not live by bread alone, but cancer in animals appears less resilient, according to a study that found chemotherapy drugs work better when combined with cycles of short, severe fasting.

9 Feb 2012

Scientists study a botanical formula that kills aggressive prostate cancer tumors

Scientists at Indiana University, Methodist Research Institute study a botanical formula that kills aggressive prostate cancer tumors. Their findings, based on experiments in mice using a human prostate cancer tumor model, appear online in The International Journal of Oncology.

9 Feb 2012

Primary nitinol stent implantation effective in treating atherosclerosis than balloon angioplasty

A three-year follow-up study has shown that an alternate treatment for obstructed arteries in the leg may be warranted. The results are from a clinical trial comparing primary nitinol stent implantation with balloon angioplasty. This examination of the study provides a long-term assessment of the two procedures, which is favorable for the primary stent.

9 Feb 2012

Mary Ann Liebert to launch BioResearch Open Access in March

BioResearch Open Access, a new bimonthly peer-reviewed open access journal, will launch in March 2012 by Mary Ann Liebert, Inc., publishers.

9 Feb 2012

Genzyme announces four-year data from eliglustat tartrate phase 2 trial on Gaucher disease type 1

Genzyme, a Sanofi company, announced today four-year follow-up data from patients enrolled in the phase 2 clinical trial for its investigational oral therapy for Gaucher disease type 1 known as eliglustat tartrate.

8 Feb 2012

New combination laser therapy effective in treating melasma

On the surface, it would seem as though the skin condition melasma (commonly referred to as the "mask of pregnancy") and tattoos would have little in common. However, they both affect a person's skin, can be quite difficult to treat or remove and, now, dermatologists are discovering new laser therapies which enhance treatment for both conditions.

8 Feb 2012