Protein C News and Research

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Chronic Urticaria: Addressing unmet needs, emerging therapies, and advances in personalized treatment approaches

Emerging personalized treatment approaches for chronic urticari.

16 Jul 2024

Harnessing brain proteins for enhanced diabetes and weight-loss drugs

A network of proteins found in the central nervous system could be harnessed to increase the effectiveness and reduce the side effects of popular diabetes and weight-loss drugs, according to new research from the University of Michigan.

15 Jul 2024

Low-GI Mediterranean diet boosts quality of life but not sleep in diabetes-prone adults

Researchers found that a low-glycemic index Mediterranean diet improves some aspects of health-related quality of life but not sleep in adults at risk for type 2 diabetes.

15 Jul 2024

Immune protein C1q impacts neuronal protein synthesis in the aging brain, study reveals

A groundbreaking study conducted at the lab of Beth Stevens, PhD, at Boston Children's Hospital has revealed that an immune protein impacts neuronal protein synthesis in the aging brain.

15 Jul 2024

Researchers discover key functions of IRF1 in cancer progression and treatment response

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have uncovered new details about the role of a protein called interferon regulatory factor (IRF1) in cancer progression and treatment response, offering new insight that can potentially help improve the effectiveness of cancer immunotherapy.

15 Jul 2024

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children's Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted antioxidants could reduce the effects of the virus while avoiding viral gene mutation resistance, a strategy that may be useful for treating other viruses.

15 Jul 2024

SH2B1 gene defends against obesity via the paraventricular hypothalamus

Obesity is a complicated condition, caused by a combination of genetics, the food environment, behavior, and other factors.

15 Jul 2024

Genetic marker predicts gabapentin response in chronic pelvic pain

Women who carry a particular form of a pain gene are more likely to respond well to a common medication used to treat long-term discomfort, research shows.

15 Jul 2024

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

With the award for up to $27 million from the Advanced Research Projects Agency for Health (ARPA-H), a collaborative research project at the Wyss Institute for Biologically Inspired Engineering at Harvard University will advance a disease-agnostic novel RNA therapeutic with the potential to treat diverse diseases, and to be effectively and rapidly deployable.

15 Jul 2024

Unraveling the role of liquid-liquid phase separation in neurodegenerative diseases

Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study.

15 Jul 2024

New guidance for assessing muscle-building supplement use in teens and young adults

A commentary published in the Journal of Adolescent Health concludes that the use of muscle-building dietary supplements among adolescents and young adults, particularly boys and young men, is widespread and driven by pressures to adhere to the muscular and lean body ideal.

15 Jul 2024

One-time prime editing targets common genetic cause of cystic fibrosis

Researchers optimized prime editing for the efficient correction of the cystic fibrosis transmembrane conductance regulator F508del mutation in human airway epithelial cells, achieving high correction efficiencies and functional restoration with minimal off-target effects.

15 Jul 2024

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Tirzepatide, a novel twincretin drug, significantly improves weight loss and glycemic control in obese and type 2 diabetes patients, outperforming traditional treatments in clinical trials.

15 Jul 2024

Hidden threats in plant-based diets: Rising allergies to lesser-known legumes

Researchers have identified emerging legume allergens like peas, lentils, and lupines, calling for more extensive studies and better diagnostics to manage increasing allergic reactions. The popularity of plant-based diets has brought new allergenic challenges to light.

15 Jul 2024

TurCaMPb: A novel tool for monitoring mitochondrial calcium dynamics

Mitochondria are crucial for maintaining calcium balance in cells, but their calcium dynamics are challenging to study due to pH changes in the mitochondrial matrix, and the lack of cyan-colored GECIs hinders the monitoring of calcium signals across different organelles and cell types.

14 Jul 2024

Study reveals how inflammation weakens muscles during illness

Infections and neurodegenerative diseases cause inflammation in the brain. But for unknown reasons, patients with brain inflammation often develop muscle problems that seem to be independent of the central nervous system. Now, researchers at Washington University School of Medicine in St. Louis have revealed how brain inflammation releases a specific protein that travels from the brain to the muscles and causes a loss of muscle function.

13 Jul 2024

Common therapies contain different cell types, study finds

Researchers from University of California San Diego have found that two of the most frequently administered stem cell therapies, which are often used interchangeably, actually contain completely different types of cells. The results challenge the current "one-cell-cures-all" paradigm in orthopedic stem cell therapeutics and highlight the need for more informed and rigorous characterization of injectable stem cell therapies before they are marketed for use in patients.

13 Jul 2024

Protein C News and Research

Chronic Urticaria: Addressing unmet needs, emerging therapies, and advances in personalized treatment approaches

Harnessing brain proteins for enhanced diabetes and weight-loss drugs

Low-GI Mediterranean diet boosts quality of life but not sleep in diabetes-prone adults

Immune protein C1q impacts neuronal protein synthesis in the aging brain, study reveals

Researchers discover key functions of IRF1 in cancer progression and treatment response

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

SH2B1 gene defends against obesity via the paraventricular hypothalamus

Genetic marker predicts gabapentin response in chronic pelvic pain

ARPA-H funding boosts Wyss Institute's RNA therapeutic project

Unraveling the role of liquid-liquid phase separation in neurodegenerative diseases

New guidance for assessing muscle-building supplement use in teens and young adults

One-time prime editing targets common genetic cause of cystic fibrosis

Twincretin drug Tirzepatide shows unmatched efficacy in weight loss and diabetes management

Hidden threats in plant-based diets: Rising allergies to lesser-known legumes

TurCaMPb: A novel tool for monitoring mitochondrial calcium dynamics

Study reveals how inflammation weakens muscles during illness

Common therapies contain different cell types, study finds

New tech aims to create marbling in plant-based meat

New threshold for CXCL13 concentration revolutionizes neuroborreliosis diagnosis

Novel DNA aptamers of melanopsin developed to regulate circadian rhythm

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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