Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Researchers identify new cancerous cells responsible for acute myeloid leukemia relapse

McMaster University researchers have provided evidence of new cancerous cells they have termed cancer regenerating cells, which are responsible for the return of acute myeloid leukemia after remission.

10 Sep 2018

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

UC San Francisco researchers have discovered how a mutation in a gene regulator called the TERT promoter -- the third most common mutation among all human cancers and the most common mutation in the deadly brain cancer glioblastoma -- confers "immortality" on tumor cells, enabling the unchecked cell division that powers their aggressive growth.

10 Sep 2018

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

UCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption.

10 Sep 2018

A joint effort to provide new insights into how gene activity drives cartilage development

Anyone with arthritis can appreciate how useful it would be if scientists could grow cartilage in the lab. To this end, Keck School of Medicine of USC scientists in the USC Stem Cell laboratory of Denis Evseenko, MD, PhD, collaborated with colleagues at several institutions to provide new insights into how gene activity drives the development of cartilage.

7 Sep 2018

Meet Axol Bioscience at 2018 Cambridge International Stem Cell Symposium

We are very pleased to support the 6th Cambridge International Stem Cell Symposium from 19 - 21 September. The annual event held by the University of Cambridge will bring together more than 400 delegates, from students to professors, to discuss the biggest fundamental and translational questions as well as celebrate the great advances being made in stem cell biology all around the world.

From Axol Bioscience Ltd 7 Sep 2018

Mimicking Human Brain Development Using Organoids

Dr. Paul Tesar from the Tesar Laboratory at Case Western University, Ohio, discusses the importance of organoids in biological research and the development of organoids which are capable of simulating the early stages of human myelin.

7 Sep 2018

Researchers develop rapid, cost-effective method to create human cortical organoids

Writing in the current online issue of the journal Stem Cells and Development, researchers at University of California San Diego School of Medicine describe development of a rapid, cost-effective method to create human cortical organoids directly from primary cells.

7 Sep 2018

Study identifies intrinsic cell properties that influence fate of neural stem cells

Researchers from the University of California, Irvine have identified intrinsic cell properties that influence the fate of neural stem cells, affecting what type of brain cell they will form: neurons, astrocytes, or oligodendrocytes.

7 Sep 2018

Research team identifies new therapeutic target for castration-resistant prostate cancer

A collaborative research team has linked the development of castration-resistant prostate cancer and resistance to treatment to a lack of androgen receptor expression in prostate cancer cells, identifying a new therapeutic target for one of the deadliest forms of cancer among men.

7 Sep 2018

UCLA Mattel Children's Hospital recognized as one of the most innovative children's hospitals in the U.S.

Parents magazine has named UCLA Mattel Children's Hospital one of the most innovative children's hospitals in the United States.

6 Sep 2018

Researchers program open wound cells to turn into healthy skin

Researchers at the Salk Institute have found a way to convert the cells in open wounds into new skin cells, potentially eliminating the need for plastic surgery in the treatment of large wounds.

6 Sep 2018

Hypertension drugs may be used to preserve memory of lupus patients

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus.

5 Sep 2018

Tipping the scales to initiate tumorigenesis in the colon

The regulatory protein c-MYC plays an important role in promoting the development of many types of tumors. c-MYC is a transcription factor that controls the activity of large numbers of genes involved in cell division, and its overexpression leads to excessive cell proliferation.

5 Sep 2018

Researchers discover how a protein complex safeguards against certain brain tumors

Researchers have discovered how a molecule can help prevent certain types of brain tumors by recognizing and 'disarming' harmful proteins that cause them.

5 Sep 2018

Huntington's disease may take effect much earlier in life than previously believed, study suggests

A new study published in the Proceedings of the National Academy of Sciences suggests that Huntington's disease may take effect much earlier in life than was previously believed, and that a new drug may be key in controlling the disease.

5 Sep 2018

New study demonstrates tissue regenerative potential of chemoattractant delivery system

A new study has demonstrated the tissue regenerative potential of a chemoattractant delivery system that can draw mesenchymal stem cells (MSCs) to the site of intervertebral disc (IVD) degeneration.

5 Sep 2018

Research reveals noise-canceling mechanisms in developmental biology

Noise is usually considered a nuisance, for example when preventing us from clearly hearing what someone is saying. The general concept of noise applies more broadly. In biology, the physical differences between organisms of the same type, for example two humans, originate from so-called developmental noise -- ultimately stemming from probabilistic collisions between reacting molecules and environmental conditions in cells during the early stages of the organism's growth.

4 Sep 2018

Stem Cells News and Research

Further Reading

Researchers identify new cancerous cells responsible for acute myeloid leukemia relapse

Researchers uncover secret of immortality mechanism in aggressive glioblastoma

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

A joint effort to provide new insights into how gene activity drives cartilage development

Meet Axol Bioscience at 2018 Cambridge International Stem Cell Symposium

Mimicking Human Brain Development Using Organoids

Researchers develop rapid, cost-effective method to create human cortical organoids

Study identifies intrinsic cell properties that influence fate of neural stem cells

Research team identifies new therapeutic target for castration-resistant prostate cancer

UCLA Mattel Children's Hospital recognized as one of the most innovative children's hospitals in the U.S.

Researchers program open wound cells to turn into healthy skin

Hypertension drugs may be used to preserve memory of lupus patients

Tipping the scales to initiate tumorigenesis in the colon

Researchers discover how a protein complex safeguards against certain brain tumors

Huntington's disease may take effect much earlier in life than previously believed, study suggests

New study demonstrates tissue regenerative potential of chemoattractant delivery system

Research reveals noise-canceling mechanisms in developmental biology

Researchers identify Zika virus proteins with potential to affect brain development

Study: Matcha green tea kills breast cancer stem cells

Cancer-hunting stem cells may be potential drug delivery tool for medulloblastoma

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