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HCCI's report shows facility prices outpaced general inflation for the privately insured under 65

Rising prices for care were the chief driver of health care costs for privately insured Americans in 2010, according to the first report from the newly formed Health Care Cost Institute.

21 May 2012

Cobiprostone shows promise against NSAID-induced gastric mucosal injury

Sucampo Pharmaceuticals, Inc. today announced the presentation of preclinical data at Digestive Disease Week 2012, in San Diego, which demonstrates the protective effect of cobiprostone against epithelial barrier dysfunction in models of non-steroidal anti-inflammatory drug (NSAID)-induced gastric mucosal injury.

21 May 2012

RA drug effective against Entamoeba histolytica

Research by a collaborative group of scientists from UC San Diego School of Medicine, UC San Francisco and Wake Forest School of Medicine has led to identification of an existing drug that is effective against Entamoeba histolytica. This parasite causes amebic dysentery and liver abscesses and results in the death of more than 70,000 people worldwide each year.

21 May 2012

Auranofin effective against amoebas in lab and animal studies

A team of researchers from UCSF and UC San Diego has identified an approved arthritis drug that is effective against amoebas in lab and animal studies, suggesting it could offer a low-dose, low cost treatment for the amoebic infections that cause human dysentery throughout the world.

21 May 2012

Statin therapy prevents cancer and reduces death risk in heart transplant recipients

Statins prevent cancer and reduce death from all causes in heart transplant recipients. The findings were independent of cholesterol levels.

21 May 2012

Study identifies biomarkers that predict patients' response to certain colon cancer drugs

The Stem Cells and Cancer Research Group headed by Dr H-ctor G. Palmer at the Vall d'Hebr-n Institute of Oncology (VHIO) has identified the molecular mechanisms that determine patients' response to certain drugs used in clinical trials for colon cancer treatment. The study led by VHIO also benefited from the collaboration with Professor Alberto Mu-oz-s laboratory at the Instituto de Investigaciones Biomedicas Alberto Sols, Consejo Superior de Investigaciones Cient-ficas.

21 May 2012

Study uncovers mechanism by which Notch pathway could contribute to RA

A new study led by researchers at Hospital for Special Surgery identifies the mechanism by which a cell signaling pathway contributes to the development of rheumatoid arthritis (RA). In addition, the study provides evidence that drugs under development for diseases such as cancer could potentially be used to treat RA.

21 May 2012

Three-drug combo harmful for patients with idiopathic pulmonary fibrosis

A combination of three drugs used worldwide as the standard of care for a serious lung disease puts patients in danger of death or hospitalization, and should not be used together to treat the disease, called idiopathic pulmonary fibrosis, according to the surprising results of a rigorous independent study.

21 May 2012

FDA gives patients less-expensive option, approves first generic versions of Plavix

Patients taking the popular blood thinner Plavix now have the option of getting a less-expensive pill, following the approval Thursday of the first generic versions in the U.S. That's because the patent for Plavix, the world's second-best-selling medicine, just expired. Plavix is taken by millions of people every day to prevent heart attacks and strokes, by preventing platelets in the blood from clumping together.

19 May 2012

Further examination of key findings of Policy Innovation Memorandum on safety of world drug, vaccine supply

In this post on her blog, "The Garrett Update" -- the last of a series of posts examining the safety of drugs and vaccines -- Laurie Garrett, senior fellow for global health at the Council on Foreign Relations (CFR), further details the key findings of the CFR's Policy Innovation Memorandum No. 21, a six-point policy recommendation for the G8/20 that she authored, titled "Ensuring the Safety and Integrity of the World's Drug, Vaccine, and Medicines Supply."

19 May 2012

Research demonstrates how a living cell controls its growth process

A collaboration between Lehigh University physicists and University of Miami biologists addresses an important fundamental question in basic cell biology: How do living cells figure out when and where to grow?

19 May 2012

New system detects residues of livestock drugs in baby food preparations

The quantities are very small, but in milk powder and in meat-based baby food, residues of drugs given to livestock were found. Researchers from the University of Almeria have developed a system to analyse these substances quickly and precisely.

19 May 2012

Specialized high volume centers linked with lower rates of death and disability from aSAH

People with bleeding brain aneurysms have the best chance of survival and full recovery if they receive aggressive emergency treatment from a specialized team at a hospital that treats a large number of patients like them every year, according to new guidelines just published by the American Stroke Association.

19 May 2012

AACN to honor Seattle nurse with Flame of Excellence Award

The American Association of Critical-Care Nurses (AACN) will present the Flame of Excellence Award to Carol Jacobson, RN, MN, for her efforts to educate progressive care and critical care nurses in the care of patients with cardiac disease.

19 May 2012

Ocera’s Zysa receives CE Mark to treat IBS-d

Ocera Therapeutics Inc., a privately-held biopharmaceutical company focused on the development and commercialization of proprietary agents to treat gastrointestinal and liver diseases, announced today that it has received a CE Mark for Zysa (spherical carbon adsorbent, formerly AST-120) for the treatment of diarrhea predominant IBS (IBS-d), a condition affecting 10-15% of the Western world.

19 May 2012

IAS’ XIX International AIDS Conference to take place in Washington D.C.

This summer, more than 25,000 leading scientists, public health experts, policy-makers, community members, and experts in the HIV/AIDS field from around the world will gather in our nation's capital for the International AIDS Society's XIX International AIDS Conference.

19 May 2012

Mount Sinai cancer researchers to present several landmark studies at ASCO meeting

Mount Sinai School of Medicine researchers will present several landmark studies, including data on treatment trends in late-stage cancer, a promising multiple myeloma vaccine, and predictive models of soft tissue sarcomas, prostate and bladder cancer, at the 2012 American Society of Clinical Oncology (ASCO) meeting June 1-5, 2012 in Chicago.

19 May 2012

Researchers identify mechanism by which Zds1 protein regulates key function in mitosis

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) have identified the mechanism by which protein Zds1 regulates a key function in mitosis, the process that occurs immediately before cell division.

19 May 2012

Screening lung cancer tumor samples for genetic mutations can help tailor personalized treatment

Screening lung cancer tumor samples for cancer-causing, or "driver," genetic mutations can help physicians tailor patients' treatments to target those specific mutations. While scientists have identified cancer-causing mutations for the majority of lung adenocarcinomas — the most common type of non-small cell lung cancer — and have developed drugs that can successfully address them, scientists have not yet identified targeted therapies for another type of non-small cell lung cancer known as squamous cell carcinoma.

19 May 2012

Sigmoid provides financial and product development update

Sigmoid Pharma Ltd., a privately-owned, specialty pharmaceutical and drug delivery company registered in Ireland, today provides an update on significant progress in 2011 and 2012.

19 May 2012

Drugs News and Research

HCCI's report shows facility prices outpaced general inflation for the privately insured under 65

Cobiprostone shows promise against NSAID-induced gastric mucosal injury

RA drug effective against Entamoeba histolytica

Auranofin effective against amoebas in lab and animal studies

Statin therapy prevents cancer and reduces death risk in heart transplant recipients

Study identifies biomarkers that predict patients' response to certain colon cancer drugs

Study uncovers mechanism by which Notch pathway could contribute to RA

Three-drug combo harmful for patients with idiopathic pulmonary fibrosis

FDA gives patients less-expensive option, approves first generic versions of Plavix

Further examination of key findings of Policy Innovation Memorandum on safety of world drug, vaccine supply

Research demonstrates how a living cell controls its growth process

New system detects residues of livestock drugs in baby food preparations

Specialized high volume centers linked with lower rates of death and disability from aSAH

AACN to honor Seattle nurse with Flame of Excellence Award

Ocera’s Zysa receives CE Mark to treat IBS-d

IAS’ XIX International AIDS Conference to take place in Washington D.C.

Mount Sinai cancer researchers to present several landmark studies at ASCO meeting

Researchers identify mechanism by which Zds1 protein regulates key function in mitosis

Screening lung cancer tumor samples for genetic mutations can help tailor personalized treatment

Sigmoid provides financial and product development update

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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