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First trial to investigate new drug combination for NSCLC

Cancer Research UK's Drug Development Office has opened the first trial of a new drug combination in patients with advanced solid tumours and in a subset of patients who have non-small cell lung cancer. This trial will combine two compounds that aim to starve the tumours while simultaneously blocking cancer cell growth.

17 May 2012

Immediate response required to curb spread of artemisinin-resistant malaria in Burma

In this Wall Street Journal opinion piece, Jay Winsten, associate dean at the Harvard School of Public Health, and Trish Stroman, a principal at the Boston Consulting Group, examine "the emergence in Southeast Asia of malarial parasites resistant to artemisinin -- the current gold-standard drug for treating the disease," writing it "poses grave new challenges."

17 May 2012

Specific organometallic substances offer new hope for treatment against tapeworm infection

Scientists are reporting development and testing of a new series of drugs that could finally stop the fox tapeworm - which causes a rare but life-threatening disease in humans - dead in its tracks. The report, which appears in ACS' Journal of Medicinal Chemistry, shows that specific organometallic substances that help combat cancer are also the surprising best new hope for a treatment against tapeworm infection.

17 May 2012

Project aims to find new diagnostic tools, drugs for triple negative breast cancer

Some types of breast cancer can be successfully treated with drugs such as tamoxifen, but treatment for a type of breast cancer more common in young and black women is still limited to radiation and general chemotherapy. Called triple negative breast cancer, this type of cancer is the focus of a 20-month, $8.6-million research project that aims to find new diagnostic tools and options for drugs.

17 May 2012

La. panel kills health exchange plan; Kansas enacts another abortion hurdle; Utah official resigns after medical records breach

With a decisive 8-1 vote late Tuesday evening, the Louisiana Senate Finance Committee buried a bill that would have set up a body of elected and appointed officials to craft the exchanges that are an anchor of President Barack Obama's health insurance overhaul. With the death of Senate Bill 744, Louisiana remains one of a handful of states that have refused to set up their own exchanges, with Gov. Bobby Jindal punting the job back to federal government that he accuses of taking over the American health care system

17 May 2012

FDA decides to strengthen warning labels on oral contraceptive YAZ, Yasmin

The Federal Drug Administration (FDA) has recently decided to strengthen warning labels on the oral contraceptive YAZ and its sister drug Yasmin regarding increased risks of blood clots from using the medications.

17 May 2012

Dako, VARI partner to license, manufacture and distribute cancer diagnostics

Van Andel Research Institute (VARI) and Dako, the Danish-based, worldwide supplier of cancer diagnostic tools today announce an agreement to license, manufacture and distribute cancer diagnostics utilizing the MET4 Antibody.

17 May 2012

Early drug and alcohol use associated with lower levels of educational attainment

Researchers have found evidence that early drug and alcohol use is associated with lower levels of educational attainment.

17 May 2012

Combination of daclizumab and vaccine improves survival of breast cancer patients

A team from the Perelman School of Medicine and the Abramson Family Cancer Research Institute at the University of Pennsylvania found that the FDA-approved drug daclizumab improved the survival of breast cancer patients taking a cancer vaccine by 30 percent, compared to those patients not taking daclizumab.

17 May 2012

Hitting the target: IntelliCap provides reliable and accurate regional drug delivery

Medimetrics, recently certified to ISO 13485, has successfully developed the IntelliCap system, specifically designed to target delivery of small molecule drugs and biologics to the gastrointestinal (GI) tract. The technology is capable of achieving controlled release of drugs to specific GI sites in a fast, cost-effective and convenient manner (Shimizu et al., 2008).

16 May 2012

New directions and challenges in viral hepatitis care and research

The editors of Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute, are pleased to announce the publication of this year's highly anticipated special 13th issue. Published each May, the 13th issue is devoted to a particular gastroenterological topic of broad interest; this year's topic is viral hepatitis.

16 May 2012

Dangerous, complex migraines linked to high risk for stroke

Nicole Soriano had headaches before but nothing like the one that struck in the middle of one summer night. A coincidence led nine days later to Cedars-Sinai Medical Center, where a rare type of migraine was diagnosed and treated - but any moment during that time could have been disastrous.

16 May 2012

CINJ prefers more personalized approach to prescribing cancer treatment

With recent advancements in technology and biomedical informatics, a more personalized approach to prescribing cancer treatment and developing these therapies is preferred over "one-size-fits-all" methods.

16 May 2012

First Edition: May 16, 2012

Today's headlines highlight the growing partisan faultlines regarding budget issues, including spending cuts and entitlement reforms.

16 May 2012

New hormone link between obesity and type 2 diabetes

A new link between obesity and type 2 diabetes found in mice could open the door to exploring new potential drug treatments for diabetes, University of Michigan Health System research has found.

16 May 2012

First patient included in the phase II study of Amphinex® in head and neck cancer patients

PCI Biotech (PCIB) the Norwegian biopharmaceutical company, reported today that the first patient has been included in the phase II study of Amphinex in combination with the cytotoxic agent bleomycin in head and neck cancer patients, called the ENHANCE study. The first patient was included at the National Center for Tumor Diseases (NCT), University Hospital Heidelberg, Germany. NCT is a joint project of the German Cancer Research Center (DKFZ), Heidelberg University Hospital, Thoraxklinik Heidelberg and Deutsche Krebshilfe (German Cancer Aid).

16 May 2012

Researchers map processes that power health benefits of omega-3 fatty acids

For the first time, researchers at the University of California, San Diego have peered inside a living mouse cell and mapped the processes that power the celebrated health benefits of omega-3 fatty acids. More profoundly, they say their findings suggest it may be possible to manipulate these processes to short-circuit inflammation before it begins, or at least help to resolve inflammation before it becomes detrimental.

16 May 2012

Scientists identify and prioritize genes associated with schizophrenia

An Indiana University-led research team, along with a group of national and international collaborators, has identified and prioritized a comprehensive group of genes most associated with schizophrenia that together can generate a score indicating whether an individual is at higher or lower risk of developing the disease.

16 May 2012

Reducing off-label antipsychotic use may generate savings with little impact on patient care

Reducing the non-FDA-approved use of antipsychotic drugs may be a way to save money while having little effect on patient care, according to a Penn State College of Medicine study.

16 May 2012

Policy Innovation Memorandum examines safety of world drug, vaccine supply

"The world is facing two immediate health crises concerning drugs and vaccines: affordable and reliable access to life-sparing medicines and the safety and reliability of those medicines," Laurie Garrett, senior fellow for global health at the Council on Foreign Relations (CFR), writes in the council's Policy Innovation Memorandum No. 21, titled, "Ensuring the Safety and Integrity of the World's Drug, Vaccine, and Medicines Supply."

16 May 2012

Drugs News and Research

First trial to investigate new drug combination for NSCLC

Immediate response required to curb spread of artemisinin-resistant malaria in Burma

Specific organometallic substances offer new hope for treatment against tapeworm infection

Project aims to find new diagnostic tools, drugs for triple negative breast cancer

La. panel kills health exchange plan; Kansas enacts another abortion hurdle; Utah official resigns after medical records breach

FDA decides to strengthen warning labels on oral contraceptive YAZ, Yasmin

Dako, VARI partner to license, manufacture and distribute cancer diagnostics

Early drug and alcohol use associated with lower levels of educational attainment

Combination of daclizumab and vaccine improves survival of breast cancer patients

Hitting the target: IntelliCap provides reliable and accurate regional drug delivery

New directions and challenges in viral hepatitis care and research

Dangerous, complex migraines linked to high risk for stroke

CINJ prefers more personalized approach to prescribing cancer treatment

First Edition: May 16, 2012

New hormone link between obesity and type 2 diabetes

First patient included in the phase II study of Amphinex® in head and neck cancer patients

Researchers map processes that power health benefits of omega-3 fatty acids

Scientists identify and prioritize genes associated with schizophrenia

Reducing off-label antipsychotic use may generate savings with little impact on patient care

Policy Innovation Memorandum examines safety of world drug, vaccine supply

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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