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Alnylam commences ALN-PCS Phase I trial in severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-PCS, an RNAi therapeutic targeting proprotein convertase subtilisin/kexin type 9, or PCSK9, for the treatment of severe hypercholesterolemia.

27 Sep 2011

Collegium completes Type A meeting with FDA for COL-003 Phase III chronic low back pain study

Collegium Pharmaceutical, Inc., a specialty pharmaceutical company, announced today that it has successfully completed a Type A meeting with the U.S. Food and Drug Administration (FDA) regarding the proposed Phase III clinical study for COL-003, the Company's tamper-resistant, extended release oxycodone product utilizing its proprietary DETERx technology.

27 Sep 2011

Aesculap acquires assets of Aragon Surgical

Aesculap announced today that it has acquired the assets of Aragon Surgical, Inc. Aragon Surgical specializes in advanced radio frequency (RF) electrosurgical instruments for tissue fusion and cutting.

27 Sep 2011

Pacira announces data from EXPAREL clinical study presented at ASPS 2011 meeting

Pacira Pharmaceuticals, Inc. today announced that the company's lead investigational product for postsurgical pain management, EXPAREL, was highlighted in the "Hot Topics in Plastic Surgery" panel at the annual scientific assembly of the American Society of Plastic Surgeons (ASPS) in Denver, Colo.

26 Sep 2011

World's first treatment of metastasized brain cancer uses IsoRay's Cesium-131 brachytherapy seeds

IsoRay, a medical technology company and innovator in seed brachytherapy and medical radioisotope applications, announced today that doctors at New York Presbyterian Hospital/ Weill Cornell Medical Center have performed the world's first treatment of metastasized brain cancer using IsoRay's Cesium-131 brachytherapy seeds.

26 Sep 2011

Gold nanowires in engineered cardiac patches could help heart attack patients

A team of physicians, engineers and materials scientists at Children's Hospital Boston and the Massachusetts Institute of Technology have used nanotechnology and tiny gold wires to engineer cardiac patches, with cells all beating in time, that could someday help heart attack patients.

26 Sep 2011

Percutaneous hepatic perfusion extends survival time for melanoma patients

Melanoma of the eye frequently spreads to the liver and, once this has happened, there is no effective treatment and patients die within an average of two to four months. Only about one in ten patients live for a year. Now, final results from a phase III study have demonstrated that a new treatment significantly extends the time patients can live without the disease progressing.

26 Sep 2011

Vaxent, PREVENT sign license agreement to develop and commercialize Strep-A vaccine

An international collaboration between Vaxent, a Memphis-based early stage vaccine development company in the Memphis Bioworks Foundation Incubator, and The Pan-Provincial Vaccine Enterprise Inc. (PREVENT), a Centre of Excellence for Commercialization and Research (CECR) in Saskatchewan, has put a vaccine for group A streptococcus (Strep-A) back on the path for potential commercialization.

26 Sep 2011

UofL receives Coulter Foundation grant for translational research

University of Louisville bioengineering researchers will use a $3.33 million award from the Wallace H. Coulter Foundation to help commercialize promising academic innovations into medical solutions to benefit patients.

26 Sep 2011

Isis files patent infringement lawsuit against Santaris for antisense drugs

Isis Pharmaceuticals, Inc. announced today it has filed a patent infringement lawsuit against Santaris Pharma A/S and Santaris Pharma A/S Corp. in the United States District Court of the Southern District of California.

26 Sep 2011

SAMHSA announces new grants to support expansion of health information technology

The Substance Abuse and Mental Health Services Administration (SAMHSA) is announcing up to $13.2 million in new grants to support the expansion of health information technology (HIT) in health care settings that serve people with mental and substance use disorders.

26 Sep 2011

OU to host 2011 International WaTER Conference

The WaTER (Water Technologies for Emerging Regions) Center at the University of Oklahoma is bringing together researchers and advocates from around the world to focus on the life-sustaining resource, clean water.

26 Sep 2011

Researchers identify micro-RNA that regulates learning processes, Alzheimer's

Proteins are the molecular machines of the cell. They transport materials, cleave products or transmit signals - and for a long time, they have been a main focus of attention in molecular biology research. In the last two decades, however, another class of critically important molecules has emerged: small RNA molecules, including micro-RNAs. It is now well established that micro-RNAs play a key role in the regulation of cell function."A micro-RNA regulates the production of an estimated 300-400 proteins.

26 Sep 2011

Embryonic stem cell therapy for incurable Stargardt eye disease

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26 Sep 2011

Study highlights individual and combined effect of obesity on asthma development

Belly fat, known clinically as central obesity, has been linked to the development of asthma in a new study.

26 Sep 2011

University of Utah develops video game to help children with cancer

Even super heroes need a chance to get better, especially if they've been fighting their arch-nemesis and a robotic crab that just won't go away. At least, that's the premise behind a video game developed at the University of Utah to help children with cancer during their treatment.

26 Sep 2011

Capital BlueCross goes live with TriZetto's care management application

The TriZetto Group, Inc. today announced that Capital BlueCross, the leading health insurer in central Pennsylvania and the Lehigh Valley, recently went live with TriZetto's Clinical CareAdvance® 4.61 care management application.

23 Sep 2011

Gamma radiation could toughen up plastic prosthetic joints

A blast of gamma radiation could toughen up plastic prosthetic joints to make them strong enough to last for years, according to researchers in China writing in the current issue of the International Journal of Biomedical Engineering and Technology.

23 Sep 2011

First Annual ACR Imaging Informatics Summit and Dose Monitoring Forum to be held from Nov. 3-4

Top radiology and policy experts will offer solutions to critical imaging informatics and radiation dose challenges at the First Annual ACR Imaging Informatics Summit and Dose Monitoring Forum.

23 Sep 2011

TeleTracking named 'Tech Titan of the Year' for second straight year

TeleTracking Technologies, Inc. was named 'Tech Titan of the Year' for the second straight year at the Pittsburgh Technology Council's Tech 50 Awards, which annually honors the most successful and innovative companies in southwestern Pennsylvania's burgeoning technology sector.

23 Sep 2011