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Cell signaling hormone boosts immune response to clear HIV-like infection

Australian scientists have successfully cleared a HIV-like infection from mice by boosting the function of cells vital to the immune response.

4 Feb 2011

MedAssurant, UNC to assess relationship between insulin and cancer development

MedAssurant, a leading provider of data-driven healthcare solutions, today announced the initiation of a joint study with the University of North Carolina to assess the relationship between the use of long-acting insulin to treat diabetes and the development of cancer.

4 Feb 2011

Scientists unravel mystery about how new tumors in individuals with breast cancer take root

In a discovery that may lead to a new treatment for breast cancer that has spread to the bone, a Princeton University research team has unraveled a mystery about how these tumors take root.

4 Feb 2011

Immune protein exacerbates skin cancer due to sun exposure: Study

An unexpected immune protein exacerbates cancer due to sun exposure, report researchers in the January 27th issue of Nature. The study suggests that drugs blocking the protein might halt tumor growth in skin cancer patients.

3 Feb 2011

FDA approves Hospira's topotecan for SCLC

Hospira, Inc., the world leader in generic injectable pharmaceuticals, today announced U.S. Food and Drug Administration (FDA) approval of Topotecan Injection, the first solution formulation of the oncology drug approved in the United States.

3 Feb 2011

Nitto Denko announces acquisition of Avecia Biotechnology

Japan's leading diversified materials manufacturer, Nitto Denko Corporation, today announced that it has acquired Avecia Biotechnology, Inc. through Nitto Americas, Inc., a wholly owned subsidiary in Teaneck, New Jersey.

3 Feb 2011

Genetic component to Parkinson’s disease discovered

Parkinson’s disease, a severely degenerative disease of the brain leading to tremors, muscle rigidity and finally immobility was until the 1990’s believed to be due to environmental factors, lifestyle and a person’s age. However, now scientists have discovered five more genes that influence its development.

3 Feb 2011

Rare new disease identified – calcium accumulates in blood vessels

A new rare disease has been identified. Louise Benge’s started having difficulty in walking when she was 25. She developed hardening and pain over her calves and hands. She worsened over the next 20 years. Her family physician in Mount Vernon, Ky., was at a loss, as were a vascular specialist, a hand specialist and a kidney specialist. Her two sisters and two brothers had the problem too, but no doctor could understand why.

3 Feb 2011

Longer life with osteoporosis therapy: Study

In a new breakthrough, Australian scientists have identified the “remarkable” life-extending properties of an osteoporosis treatment. The research is published in the Journal of Endocrinology and Metabolism on Thursday.

3 Feb 2011

Positive results from Derma Sciences' Phase 2 trial with DSC127 in patients with diabetic foot ulcers

Derma Sciences, Inc., a medical device and pharmaceutical company focused on advanced wound care, today announced positive results from its Phase 2 clinical trial with DSC127 in patients with diabetic foot ulcers, including meeting the trial's primary endpoint, the proportion of study ulcers healed by 12 weeks as defined by 100% epithelialized with no drainage, as well as all secondary endpoints measured at this time.

3 Feb 2011

Stockpiling flu drugs, vaccines reduces impact of pandemic, but option out of reach for most countries, study finds

"Stockpiling antiviral flu drugs and vaccines saves lives and reduces disease in a flu pandemic," but the cost to maintain such a stockpile and deploy interventions in the event of an outbreak "is too expensive for around two thirds of the world's population, scientists said on Wednesday," Reuters reports.

3 Feb 2011

New device to treat heart hiccups

"It took off to about 160 beats per minute and then dropped to 50. It seemed confused. Then it went back to normal," recalled Tsuji, 47, an avid cyclist, of that day in 2003. "I didn't notice any symptoms at that point, so I blew it off. I figured there was something wrong with it."

3 Feb 2011

First therapeutic vaccine designed from dendritic cells of patient achieves significant response

The therapeutic vaccines are a priority research line of the HIVACAT, the catalan programme for the development of therapeutic vaccines and prevention against the Human Immunodeficiency Virus (HIV). This type of therapeutic vaccine helps the patients who are carriers of the virus, combat infection and control the appearance of AIDS in the same way as with the current antiretroviral treatments.

3 Feb 2011

Generic drugs to treat hypertension, heart failure could help NHS save £200 million

Using a generic drug to treat hypertension and heart failure, instead of branded medicines from the same class, could save the UK National Health Service (NHS) at least £200 million in 2011 without any real reduction in clinical benefits.

3 Feb 2011

Researchers develop hard X-ray laser to determine structure of biomolecules

Unraveling the molecular basis of life is an age-old quest of humanity. A breakthrough towards this goal was reported in a pair of studies published Feb. 3 in the scientific journal Nature, detailing a new method developed to determine structures of biomolecules based on diffraction from protein nanocrystals that are so small that they are not even visible under the microscope.

3 Feb 2011

Intermittent use of preventive malaria drugs in children found to help prevent malaria transmission, studies say

Three studies published on Tuesday in PLoS Medicine show that "intermittent use of preventive antimalarial drugs can be beneficial in curbing the spread of the disease in children," Agence France-Presse reports (2/1).

3 Feb 2011

UT Southwestern leads national effort to find effective treatments for drug addiction

UT Southwestern Medical Center psychiatry researchers are leading the Texas arm of a national network that conducts clinical trials aimed at finding effective treatments for drug addiction.

3 Feb 2011

Fidaxomicin demonstrates 45% reduction in recurrences vs. existing treatment for C. difficile infection

Clostridium difficile infection (CDI) is a significant and growing problem in hospitals and other health care facilities, but no new drugs to treat the condition have been developed in several decades. However, a large-scale, phase 3 trial conducted by Canadian and U.S. researchers shows that the new antibiotic Fidaxomicin is superior to existing treatments, demonstrating a 45 percent reduction in recurrences vs. the existing licensed treatment.

3 Feb 2011

Losartan improves effectiveness of nanotherapeutics against cancer

Low doses of an inexpensive, FDA-approved hypertension medication may improve the results of nanotherapeutic approaches to cancer treatment. In a report in the early edition of Proceedings of the National Academy of Sciences, Massachusetts General Hospital (MGH) investigators describe experiments showing that the generic drug losartan, by modifying the network of collagen fibers that characterizes most solid tumors, improved the effectiveness of two nanotherapeutics against several types of cancer.

3 Feb 2011

Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

Concert Pharmaceuticals, Inc. today announced that it has entered into a Cooperative Research and Development Agreement with the Walter Reed Army Institute of Research. The CRADA will allow the WRAIR to conduct preclinical testing on a novel compound derived from Concert's DCE Platform™ (deuterated chemical entity platform) for seizure protection associated with traumatic brain injury, a major public health concern.

3 Feb 2011

Drugs News and Research

Cell signaling hormone boosts immune response to clear HIV-like infection

MedAssurant, UNC to assess relationship between insulin and cancer development

Scientists unravel mystery about how new tumors in individuals with breast cancer take root

Immune protein exacerbates skin cancer due to sun exposure: Study

FDA approves Hospira's topotecan for SCLC

Nitto Denko announces acquisition of Avecia Biotechnology

Genetic component to Parkinson’s disease discovered

Rare new disease identified – calcium accumulates in blood vessels

Longer life with osteoporosis therapy: Study

Positive results from Derma Sciences' Phase 2 trial with DSC127 in patients with diabetic foot ulcers

Stockpiling flu drugs, vaccines reduces impact of pandemic, but option out of reach for most countries, study finds

New device to treat heart hiccups

First therapeutic vaccine designed from dendritic cells of patient achieves significant response

Generic drugs to treat hypertension, heart failure could help NHS save £200 million

Researchers develop hard X-ray laser to determine structure of biomolecules

Intermittent use of preventive malaria drugs in children found to help prevent malaria transmission, studies say

UT Southwestern leads national effort to find effective treatments for drug addiction

Fidaxomicin demonstrates 45% reduction in recurrences vs. existing treatment for C. difficile infection

Losartan improves effectiveness of nanotherapeutics against cancer

Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

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Changing the landscape of R&D to build clinical success from the ground up

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