Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Given Imaging introduces new PillCam system at GASTRO 2009 Conference

Given Imaging Ltd., the global leader in capsule endoscopy, today announced the launch of its second-generation PillCam® COLON capsule at the Gastro 2009 Conference taking place in London. Like Given Imaging's other capsule endoscopes, PillCam® SB and PillCam® ESO, PillCam COLON could be a more patient-friendly tool for imaging the gastrointestinal tract.

23 Nov 2009

Boston Scientific's WallFlex Fully Covered Esophageal Stent receives FDA clearance and CE Mark approval

Boston Scientific Corporation today announced that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) and CE Mark approval to market its WallFlex® Fully Covered Esophageal Stent for the treatment of malignant esophageal strictures (obstructions) caused by tumors in patients with resectable or non-resectable esophageal cancer.

20 Nov 2009

New studies suggest elevated risk of gastrointestinal cancers in diabetic patients

There are minimal data assessing the relationship between diabetes with gallbladder, biliary and pancreatic cancer. Recent small studies have suggested an elevated risk of pancreatic cancer only in patients with diabetes mellitus (DM).

20 Nov 2009

GERD is an immune-mediated injury and not the result of acid burn, says new study

Contrary to current thinking, a condition called gastroesophageal reflux disease (GERD) might not develop as a direct result of acidic digestive juices burning the esophagus, UT Southwestern Medical Center researchers have found in an animal study.

20 Nov 2009

Gastrointestinal symptoms may interfere with nutritional management of ED patients

Eating disorders (ED) patients display a high prevalence of gastrointestinal symptoms and functional gastrointestinal disorders such as irritable bowel syndrome. These symptoms may interfere with their nutritional management. Ingestion of fructose-sorbitol (F-S) is an established means of gastrointestinal symptom provocation in irritable bowel syndrome patients.

20 Nov 2009

Embryonic stem cells raise hope of cellular replacement therapy for liver failure

Embryonic stem (ES) cells, known for their capacity to proliferate indefinitely and differentiate into almost all types of cells including hepatocytes, have raised the hope of cellular replacement therapy for liver failure. There have been several protocols available for hepatic fate specification from ES cells, however, most of the protocols currently used result in low yield or purity of functional hepatocytes. Valproic acid (VPA), a histone deacetylase inhibitor, has been demonstrated to facilitate the hepatic differentiation of mesenchymal stem cells. However, little is know about whether VPA could induce the hepatic differentiation of ES cells.

19 Nov 2009

Report on unexplained liver haemorrhage after metastasis radiofrequency ablation published

Colorectal carcinoma is one of the most common cancers in the world. Approximately one in four of these patients have metastases at diagnosis, liver being the most common site involved. Although historically it was considered that liver metastases meant a very poor prognosis, today, due to improved systemic therapy, many patients will be candidates for local hepatic treatments such as surgery or less aggressive radiofrequency ablation.

19 Nov 2009

Reduction of serum bilirubin, the hallmark of successful biliary drainage

Biliary drainage is performed as a palliative treatment of hilar cholangiocarcinoma. The reduction of serum bilirubin is usually the hallmark of successful biliary drainage. However, some patients may have persistent jaundice or scanty bile output after biliary drainage.

19 Nov 2009

Study: EP4 agonist may reduce gastric bleeding and inflammation

Over 300 million patients use non-steroidal anti-inflammatory drugs (NSAIDs) in the world to treat pain, arthritis, fever and other diseases. Nearly 30% of the users suffer from gastric lesions and bleeding.

19 Nov 2009

Experimental study shows beneficial effects of Vardenafil on NSAID-induced gastric ulcer

Indomethacin has been proved by epidemiological and experimental studies to be closely associated with peptic ulcer development. Vardenafil is a potent phosphodiesterase 5 inhibitor and its effects on the gastric mucosa havenot been reported.

19 Nov 2009

Green tea prevents the development of hepatic fibrosis in rat model of DMN-induced liver fibrosis

Several studies have shown that lipid peroxidation stimulates collagen production in fibroblasts and hepatic stellate cells (HSC), and plays an important role in the development of liver fibrosis. Hepatoprotective effects of green tea against carbon tetrachloride, cholestasis and alcohol induced liver fibrosis were reported in many studies. However, the hepatoprotective effect of green tea in dimethylnitrosamine (DMN)-induced models has not been studied.

18 Nov 2009

CONMED Linvatec produces the smallest Biocomposite Interference screw for fixation of ACL and PCL grafts

CONMED Corporation's CONMED Linvatec arthroscopy unit today announced the release of new sizes of its Matryx™ Biocomposite Interference Screw. These new screws represent the latest advance in biocomposite material technology that allows CONMED Linvatec to produce the smallest Biocomposite Interference screw available on the market today for primary fixation of ACL and PCL grafts.

17 Nov 2009

First phase of new electronic health record system launched at Trinity Center

NYU Langone Medical Center launched the first phase of its new electronic health record system last week at their multi-disciplinary faculty group practice at Trinity Center in lower Manhattan. The integrated system, powered by software from Epic Systems Corporation, provides a single platform from which physicians, staff and patients themselves can access and manage medical information.

17 Nov 2009

Bullseye Anatomic Cruciate Reconstruction System released

CONMED Corporation's CONMED Linvatec arthroscopy unit today announced the release of the Bullseye™ Anatomic Cruciate Reconstruction System, a novel guide system for anatomic cruciate ligament (ACL and PCL) reconstructions of the knee.

16 Nov 2009

Warner Chilcott to offer 20,000,000 shares in secondary offering

Warner Chilcott plc today announced a 20,000,000 share secondary offering of its ordinary shares by certain selling shareholders. The selling shareholders include funds affiliated with Bain Capital Partners, DLJ Merchant Banking, J.P. Morgan Partners (advised by CCMP Capital) and Thomas H. Lee Partners, L.P., certain other institutional investors and members of the Company's senior management. The offering is being conducted as a public offering pursuant to an effective shelf registration statement under the Securities Act of 1933. The Company will not receive any proceeds from the sale of the shares but will pay the expenses of the offering.

13 Nov 2009

Medtronic launches an educational campaign to raise awareness of overactive bladder

Medtronic, Inc. today announced the kick-off of an educational campaign aimed at raising awareness among women of overactive bladder (OAB), a serious condition that can severely impact patients’ lives. This new campaign, conducted in partnership with leading patient advocacy groups focused on women’s health will help to raise awareness of the prevalence of bladder control problems and encourage patients to find effective treatment options – including and beyond medications.

13 Nov 2009

Clinical Care Options to provide online continuing medical education in "The Oncology Portal"

Clinical Care Options (CCO), a leader in the development of innovative interactive online, print, and live medical education for healthcare professionals, today announced its exclusive collaboration with Oncology Today(TM), a wholly owned subsidiary of US Oncology, Inc., to be the provider of online continuing medical education (CME) for the newly formed US Oncology's online clinician community, "The Oncology Portal."

13 Nov 2009

Frequent heartburn is painful and impacts the quality of life: Study

While most adults have likely experienced the uncomfortable symptoms of heartburn at least once, for the 50 million American adults who suffer from frequent heartburn two or more days per week, the condition is not only painful, it can also impact their quality of life.

12 Nov 2009

GeneNews discloses financial results for third-quarter 2009

GeneNews Limited, a company focused on developing blood-based biomarker tests for the early detection of diseases and personalized health management, today reported operational and financial results for the third quarter-ended September 30, 2009.

11 Nov 2009

Lesser rates of kidney/pancreas transplants for African Americans: Is physician bias the reason?

Physician bias might be the reason why African Americans are not receiving kidney/pancreas transplants at the same rate as similar patients in other racial groups. Dr. Keith Melancon, director of kidney and pancreas transplantation at Georgetown University Hospital and associate professor of surgery at Georgetown University Medical Center, and colleagues explore this phenomenon in the November issue of the American Journal of Transplantation.

10 Nov 2009

Gastroenterology News and Research

Further Reading

Given Imaging introduces new PillCam system at GASTRO 2009 Conference

Boston Scientific's WallFlex Fully Covered Esophageal Stent receives FDA clearance and CE Mark approval

New studies suggest elevated risk of gastrointestinal cancers in diabetic patients

GERD is an immune-mediated injury and not the result of acid burn, says new study

Gastrointestinal symptoms may interfere with nutritional management of ED patients

Embryonic stem cells raise hope of cellular replacement therapy for liver failure

Report on unexplained liver haemorrhage after metastasis radiofrequency ablation published

Reduction of serum bilirubin, the hallmark of successful biliary drainage

Study: EP4 agonist may reduce gastric bleeding and inflammation

Experimental study shows beneficial effects of Vardenafil on NSAID-induced gastric ulcer

Green tea prevents the development of hepatic fibrosis in rat model of DMN-induced liver fibrosis

CONMED Linvatec produces the smallest Biocomposite Interference screw for fixation of ACL and PCL grafts

First phase of new electronic health record system launched at Trinity Center

Bullseye Anatomic Cruciate Reconstruction System released

Warner Chilcott to offer 20,000,000 shares in secondary offering

Medtronic launches an educational campaign to raise awareness of overactive bladder

Clinical Care Options to provide online continuing medical education in "The Oncology Portal"

Frequent heartburn is painful and impacts the quality of life: Study

GeneNews discloses financial results for third-quarter 2009

Lesser rates of kidney/pancreas transplants for African Americans: Is physician bias the reason?

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