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Top-line results from Genzyme's teriflunomide and Rebif Phase III comparison trial on RMS

Genzyme, a Sanofi company, today reported top-line results from TENERE, a Phase III clinical trial comparing the effectiveness, safety and tolerability of once-daily oral teriflunomide to interferon beta-1a, an approved injectable therapy, in people with relapsing forms of multiple sclerosis.

20 Dec 2011

Eculizumab protects children from severe Shiga toxin-associated HUS

A physician and researcher at the Sainte Justine University Hospital Center (Sainte-Justine UHC), a University of Montreal affiliate, saved the life of a child and, by doing so, became the first to find a new use for a drug in the fight against deadly E. coli bacteria.

20 Dec 2011

Top-line results from AstraZeneca and Targacept's TC-5214 Phase 3 study on MDD

AstraZeneca and Targacept, Inc. today announced top-line results from the second of four RENAISSANCE Phase 3 studies investigating the efficacy and tolerability of TC-5214 as an adjunct therapy to an antidepressant in patients with major depressive disorder (MDD) who do not respond adequately to initial antidepressant treatment.

20 Dec 2011

Acupuncture can reduce protein associated with chronic stress

Acupuncture significantly reduces levels of a protein in rats linked to chronic stress, researchers at Georgetown University Medical Center (GUMC) have found. They say their animal study may help explain the sense of well-being that many people receive from this ancient Chinese therapy.

20 Dec 2011

Blocking EETs may represent novel strategy for cancer therapy

Recent findings in mice suggest that blocking the production of small molecules produced in the body, known as epoxyeicosatrienoic acids (EETs), may represent a novel strategy for treating cancer by eliminating the blood vessels that feed cancer tumors.

20 Dec 2011

Routine criminal prosecutions for HIV nondisclosure should be abolished, say experts

Routine criminal prosecutions for not disclosing HIV status should be abolished, write three HIV/AIDS experts in an article in CMAJ.

20 Dec 2011

Gene therapy may promote growth of hair cells in inner ear

Normal hearing depends on the presence of healthy hair cells in the inner ear. Gene therapy has the potential to slow the loss of hair cells and promote the growth of hair cells that have already been damaged.

20 Dec 2011

Atox Bio to advance AB103 Phase 2 study with $3.25M financing

Atox Bio, developer of therapeutics for diseases mediated by an excessive inflammatory response, today announced that it has raised $3.25 million in an initial closing. The investment was co-led by Esperante and a private US-based investor and will be used to advance AB103, currently in phase 2 clinical studies for the treatment of Necrotizing Soft Tissue Infections (NSTI).

19 Dec 2011

EMA CHMP recommends approval for BioMarin's Novato manufacturing facility expansion

BioMarin Pharmaceutical Inc. announced today that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended approval for the company's manufacturing facility expansion in Novato, CA.

19 Dec 2011

MDA doctors challenge breast cancer brachytherapy study

A recent study on a sophisticated form of radiation treatment for breast cancer is inaccurate and has caused unnecessary concern among many patients, according to four top physician researchers.

19 Dec 2011

ALS TDI, Biogen Idec and UCB enter agreement to study anti-CD40L antibody for ALS

The ALS Therapy Development Institute today announced a research agreement with Biogen Idec and UCB Pharma SA to investigate the use of an anti-CD40L antibody as a potential therapy for Amyotrophic Lateral Sclerosis, also known as Lou Gehrig's or Motor Neuron Disease.

19 Dec 2011

New gel could nip Lyme borreliosis infection in the bud

They come out in the spring, and each year they spread further - the ticks. Thirty percent of them transmit borrelia pathogens, the causative agent of Lyme borreliosis that can damage joints and organs.

19 Dec 2011

Soybean compounds can increase effectiveness of radiation treatment for lung cancer

A Wayne State University researcher has shown that compounds found in soybeans can make radiation treatment of lung cancer tumors more effective while helping to preserve normal tissue.

19 Dec 2011

The Academy of Nutrition and Dietetics to expand coverage of MNT

The Academy of Nutrition and Dietetics has prepared a request to submit to the Centers for Medicare and Medicaid Services (CMS) to expand coverage of medical nutrition therapy (MNT) for specific diseases, including hypertension, obesity, and cancer, as part of the CMS National Coverage Determination (NCD) Process.

19 Dec 2011

Clinical trials highlight beneficial effect of CRT in heart failure

However, large-scale clinical trials have highlighted the beneficial effect of cardiac resynchronisation therapy (CRT) in the improvement of symptoms and reduction of mortality, and CRT is now recommended in the major European and American guidelines for the treatment and prevention of heart failure.

19 Dec 2011

Baxter receives FDA approval for ADVATE to prevent hemophilia A

Baxter International Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved ADVATE [Antihemophilic Factor (Recombinant) Plasma/Albumin Free Method] for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in patients with hemophilia A.

From Baxter International Inc. 17 Dec 2011

Combination of bevacizumab and chemoradiation safe, effective for nasopharyngeal carcinoma

The trial conducted by the Radiation Therapy Oncology Group (RTOG) shows the feasibility to deliver bevacizumab to the current chemoradiation standard without any apparent increased adverse side effects.

17 Dec 2011

Researchers discover miR-520 blocks cancer-promoting signaling pathway

MicroRNAs or miRNAs are tiny RNA molecules that have only about 20 nucleotides and do not code for proteins. They regulate many important processes in cells by binding to target messenger RNAs - the instructions for protein production -, thus blocking production of the respective protein. In cancer, the production of some miRNAs is often reduced or amplified. This particularly affects miRNAs that regulate the activity of cancer-promoting genes.

17 Dec 2011

NewYork-Presbyterian/Westchester named 'Planetree Designated Patient-Centered Hospital'

NewYork-Presbyterian Hospital's Westchester Division has been formally named by Planetree Inc. as a "Planetree Designated Patient-Centered Hospital" in recognition of the Hospital's achievement and innovation in the delivery of patient-centered care.

17 Dec 2011

Scientists devise a way to reduce side effects of lung cancer therapy

Scientists may have a way to double the efficacy and reduce the side effects of radiation therapy.

17 Dec 2011

Therapy News and Research

Top-line results from Genzyme's teriflunomide and Rebif Phase III comparison trial on RMS

Eculizumab protects children from severe Shiga toxin-associated HUS

Top-line results from AstraZeneca and Targacept's TC-5214 Phase 3 study on MDD

Acupuncture can reduce protein associated with chronic stress

Blocking EETs may represent novel strategy for cancer therapy

Routine criminal prosecutions for HIV nondisclosure should be abolished, say experts

Gene therapy may promote growth of hair cells in inner ear

Atox Bio to advance AB103 Phase 2 study with $3.25M financing

EMA CHMP recommends approval for BioMarin's Novato manufacturing facility expansion

MDA doctors challenge breast cancer brachytherapy study

ALS TDI, Biogen Idec and UCB enter agreement to study anti-CD40L antibody for ALS

New gel could nip Lyme borreliosis infection in the bud

Soybean compounds can increase effectiveness of radiation treatment for lung cancer

The Academy of Nutrition and Dietetics to expand coverage of MNT

Clinical trials highlight beneficial effect of CRT in heart failure

Baxter receives FDA approval for ADVATE to prevent hemophilia A

Combination of bevacizumab and chemoradiation safe, effective for nasopharyngeal carcinoma

Researchers discover miR-520 blocks cancer-promoting signaling pathway

NewYork-Presbyterian/Westchester named 'Planetree Designated Patient-Centered Hospital'

Scientists devise a way to reduce side effects of lung cancer therapy

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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