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Study identifies potential biomarkers associated with chemo resistant breast cancers

Biomarkers which could help to predict resistance to chemotherapy in breast cancer patients have been identified by researchers from the University of Hull, UK.

16 Apr 2012

The key to treating AML may lie within FTL3 gene mutations

The key to treating one of the most common types of human leukemia may lie within mutations in a gene called FLT3, according to new research led by physician-scientists at the University of California, San Francisco (UCSF) Helen Diller Family Comprehensive Cancer Center.

16 Apr 2012

Researchers discover new class of molecular mutation in breast cancer

Mayo Clinic researchers have discovered a new class of molecular mutation in various forms of breast cancer, a finding that may shed new light on development and growth of different types of breast tumors. Called fusion transcripts, the mutated forms of RNA may also provide a way to identify tumor subtypes and offer new strategies to treat them, investigators say.

16 Apr 2012

Targeting glucagon's sweetening effect may treat type II diabetes

Maintaining the right level of sugar in the blood is the responsibility not only of insulin, which removes glucose, but also of a hormone called glucagon, which adds glucose.

16 Apr 2012

Positive top-line results from Biodel’s Phase 1 trial of two RHI-based formulations

Biodel Inc. today announced positive top-line results from a Phase 1 clinical trial of its product candidates, BIOD-123 and BIOD-125 -- two proprietary ultra-rapid-acting formulations of recombinant human insulin.

16 Apr 2012

Roundup: Texas considers relaxing rules for stem cell treatments; States weigh bills to protect consumers against high drug costs

A Texas agency will vote Friday on whether to enact new rules that would make it easier for doctors to offer experimental treatments using adult stem cells without federal approval. The Texas Medical Board, which licenses and disciplines doctors in the state, recently drafted stem-cell rules at the behest of Dr. Stanley Jones of Houston, who in July injected Gov. Rick Perry with the governor's own stem cells to try to aid his recovery from a back injury.

16 Apr 2012

Toxic plants and animal products found in traditional Chinese medicines

A study has found that some traditional Chinese medicines contain potentially poisonous plants, unlabelled ingredients and bits of endangered animals. This has triggered a bid for routine testing and tighter regulation of complementary medicines.

15 Apr 2012

Natural products isolated from marine mollusks and sponges can reverse multidrug resistance in cancer cells

Many marine natural products show anticancer activity, but some can reverse multidrug resistance in cancer cells. A new investigation by Robert J. Capon of the University of Queensland correlates the products' structures with their activity.

12 Apr 2012

FDA urges restriction in injudicious use of antibiotics in livestock

The Food and Drug Administration (FDA) has urged drug companies Wednesday to help limit the use of antibiotics in farm animals. The researchers say that this decades-old practice has contributed to a surge in dangerous, drug-resistant bacteria.

12 Apr 2012

Longer looks: Diagnosing autism in minutes; Finding new uses for old drugs; Cancer war victories

Autism is an extremely complex diagnosis. Parental insight, physician observations and hours of data can factor into determining whether a child actually has the condition or is just a little on the quirky side. Now a Harvard researcher, Dennis P. Wall, has published research about a Web-based tool he developed that promises to diagnose autism in minutes, not hours -

12 Apr 2012

Roundup: No new policies from cross-border insurance law; Dental Medicaid abuse in Texas?

Proponents said these out-of-state policies, stripped of Georgia's mandates, would have lower premiums – and allow more people to afford individual health insurance coverage. ... But a year later, nothing has happened. No insurer here has started selling a non-Georgia health plan.

12 Apr 2012

DNDi, AstraZeneca enter collaboration on drug-compound screening for NTDs

AstraZeneca and the Drugs for Neglected Diseases initiative (DNDi) today announce an agreement to collaborate on drug-compound screening for leishmaniasis, Chagas disease, and sleeping sickness, three neglected tropical diseases (NTDs) which together affect nearly 10 million people worldwide.

12 Apr 2012

Johnson & Johnson fined $1.2B for hiding anti-psychotic drug dangers, deceptive marketing

An Arkansas judge fined the drug maker and a subsidiary for misleading doctors and the public on the risks involved with taking an anti-psychotic drug, Risperdal, and for marketing the drug for an off-label use to the state's Medicaid system.

12 Apr 2012

ALL induction treatment failure should not be an automatic indication for bone marrow transplant

International study that included St. Jude Children's Research Hospital reports some young acute lymphoblastic leukemia patients who fail induction therapy can achieve high cure rates without bone marrow transplantation.

12 Apr 2012

Newer antidepressant decreases depression in Parkinson's patients without worsening motor problems

Certain antidepressants appear to decrease depression in people with Parkinson's disease without worsening motor problems, according to a study published in the April 11, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

12 Apr 2012

Enrollment complete for Ampio's multiple indication diagnostic clinical trials

Ampio Pharmaceuticals, Inc., a company that discovers and develops new uses for previously approved drugs and new molecular entities ("NMEs"), announced today that it has completed enrollment of patients for its multiple indication diagnostic clinical trials.

12 Apr 2012

Shoes play vital role in protecting children's health, development

"As we have seen in our work in Haiti and around the world, shoes are a first level of defense when it comes to good health, and are a great complement to the Neglected Tropical Disease (NTD) Control program IMA World Health implements in Haiti," Rick Santos, president and CEO of IMA World Health, writes in the Huffington Post Blog, commemorating One Day Without Shoes, observed on Tuesday.

12 Apr 2012

Drugs News and Research

Study identifies potential biomarkers associated with chemo resistant breast cancers

The key to treating AML may lie within FTL3 gene mutations

Researchers discover new class of molecular mutation in breast cancer

Targeting glucagon's sweetening effect may treat type II diabetes

Positive top-line results from Biodel’s Phase 1 trial of two RHI-based formulations

Roundup: Texas considers relaxing rules for stem cell treatments; States weigh bills to protect consumers against high drug costs

Toxic plants and animal products found in traditional Chinese medicines

Natural products isolated from marine mollusks and sponges can reverse multidrug resistance in cancer cells

FDA urges restriction in injudicious use of antibiotics in livestock

Longer looks: Diagnosing autism in minutes; Finding new uses for old drugs; Cancer war victories

Roundup: No new policies from cross-border insurance law; Dental Medicaid abuse in Texas?

DNDi, AstraZeneca enter collaboration on drug-compound screening for NTDs

Johnson & Johnson fined $1.2B for hiding anti-psychotic drug dangers, deceptive marketing

ALL induction treatment failure should not be an automatic indication for bone marrow transplant

Newer antidepressant decreases depression in Parkinson's patients without worsening motor problems

Enrollment complete for Ampio's multiple indication diagnostic clinical trials

Shoes play vital role in protecting children's health, development

First Edition: April 12, 2012

First clinical trial to clearly demonstrate effective prevention of post-ERCP pancreatitis

Two UM events examine timely issue of medicinal marijuana use

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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