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Low vitamin D may affect recovery of injured corneas

Injury or disease in combination with too little vitamin D can be bad for the window to your eyes. The three-layer, transparent cornea at the front of the eyes focuses the light coming in. But its prominent position also puts it at risk for injury from an errant mascara wand or over-prodding finger or a car accident.

24 Jul 2017

CUMC researchers capture first snapshot of key brain receptor in action

Columbia University Medical Center researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, is involved in several important brain activities, including memory and learning.

24 Jul 2017

Likarda uses INTEGRA’s VIAFLO ASSIST to automate cell-based assay development

INTEGRA has published a new video that demonstrates how US-based biotech contract research specialists Likarda LLC are using their VIAFLO ASSIST to cost effectively develop high throughput cell based assays for their customers.

From INTEGRA Biosciences 24 Jul 2017

People with genetic susceptibility to Alzheimer's may have greater cognitive deficits with sleep-disordered breathing

People who carry a genetic susceptibility to Alzheimer's disease appear to be at greater risk of diminished cognition from sleep-disordered breathing than those without the susceptibility, according to new research published online, ahead of print in the Annals of the American Thoracic Society.

21 Jul 2017

First in-car study of rush hour pollution finds alarming results

The first in-car measurements of exposure to pollutants that cause oxidative stress during rush hour commutes has turned up potentially alarming results.

21 Jul 2017

Wayne State researchers receive $1.9 million NIH grant to better understand rare genetic disorders

A team of Wayne State University researchers recently received a $1.9 million grant from the National Eye Institute of the National Institutes of Health to better understand leukodystrophies (LD) and genetic Leukoencephalopathies (gLE), rare genetic disorders affecting the white matter -- myelin -- in the central nervous system.

21 Jul 2017

Testing treatments using pig model may help minimize drug failure rates for chronic conditions

Scientists may be able to minimize the failure rate of drugs for diseases linked to high-calorie diets, such as colon cancer and type 2 diabetes, if they test treatments using a pig model, according to an international team of researchers.

21 Jul 2017

New genomic research partnership promises to redefine and transform cancer treatment

Personalized cancer therapies are on the horizon thanks to a new genomic cancer research partnership between the Gene Editing Institute of Christiana Care Health System's Helen F. Graham Cancer Center & Research Institute and the biotechnology company NovellusDx.

21 Jul 2017

Novel model predicts single heart cell's response to dwindling supplies of oxygen

Time is of the essence when treating a patient undergoing a heart attack. Cardiac surgeons attempt to quickly stabilize the heart by applying reperfusion, a technique that restores oxygen to the heart by opening up blocked vessels with balloons and stents.

21 Jul 2017

Researchers devise strategy to target Achilles heel of nervous system cancers

Virtually all cancer treatments used today also damage normal cells, causing the toxic side effects associated with cancer treatment.

21 Jul 2017

Advanced lung cancer patients get survival benefit with use of concurrent chemotherapy, proton therapy

For patients with advanced, inoperable stage 3 lung cancer, concurrent chemotherapy and the specialized radiation treatment, proton therapy, offers improved survival compared to historical data for standard of care, according to a new study from The University of Texas MD Anderson Cancer Center.

20 Jul 2017

Epigenetic dysregulation with age in normal breast tissue may contribute to cancer risk

Several known factors are associated with a higher risk of breast cancer including increasing age, being overweight after menopause, alcohol intake, and family history.

20 Jul 2017

UAlberta researchers find strong clues to underlying cause of HIV-associated neurocognitive disorders

UAlberta researchers believe they now have a clearer picture of why people living with HIV so commonly suffer from dementia and other neurocognitive disorders.

20 Jul 2017

Researchers show how hematopoietic stem cells detect and react to infections

Researchers at the University of Zurich have shown for the first time that hematopoietic stem cells detect infectious agents themselves and begin to divide - that is, without signals from growth factors.

20 Jul 2017

Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Whether a melanoma patient will better respond to a single immunotherapy drug or two in combination depends on the abundance of certain white blood cells within their tumors, according to a new study conducted by UC San Francisco researchers joined by physicians from UCSF Health.

20 Jul 2017

Researchers find new way to protect stem cells from inflammation during wound repair

Scientists have found a new way to protect stem cells from harsh inflammation during wound repair. In a study recently published in the journal Cytotherapy, researchers in India discovered that treating mice with a common anti-inflammatory drug called celecoxib promoted stem cell survival and healing when they injected the cells into wounds.

20 Jul 2017

Methicillin use not to blame for MRSA, say researchers

The introduction of methicillin into clinical practice is not what caused the emergence of methicillin resistant Staphylococcus aureus (MRSA), report researchers. According to a collaborative study by the University of St Andrews, University of Dundee and the Wellcome Trust Sanger Institute, MRSA existed long before clinicians started using the antibiotic.

20 Jul 2017

New report highlights beneficial effects of nonmedical interventions for people with dementia

Managing lifestyle factors such as hearing loss, smoking, hypertension and depression could prevent one-third of the world's dementia cases, according to a report by the first Lancet Commission on Dementia Prevention and Care.

20 Jul 2017

Skin-applied microneedle patch boosts immunization to seasonal flu vaccine recipients, study finds

A boosting skin vaccination with a biodegradable microneedle patch and protein constructed from sequences of influenza virus subtypes could improve the effectiveness of conventional influenza vaccines, according to a study led by Georgia State University.

19 Jul 2017

Researchers identify striking contrasts in how groups of neurons function during decision making

By training mice to perform a sound identification task in a virtual reality maze, researchers at Harvard Medical School and the Istituto Italiano di Tecnologia (IIT) have identified striking contrasts in how groups of neurons in different cortex regions of the brain function during decision making.

19 Jul 2017

Cell News and Research

Low vitamin D may affect recovery of injured corneas

CUMC researchers capture first snapshot of key brain receptor in action

Likarda uses INTEGRA’s VIAFLO ASSIST to automate cell-based assay development

People with genetic susceptibility to Alzheimer's may have greater cognitive deficits with sleep-disordered breathing

First in-car study of rush hour pollution finds alarming results

Wayne State researchers receive $1.9 million NIH grant to better understand rare genetic disorders

Testing treatments using pig model may help minimize drug failure rates for chronic conditions

New genomic research partnership promises to redefine and transform cancer treatment

Novel model predicts single heart cell's response to dwindling supplies of oxygen

Researchers devise strategy to target Achilles heel of nervous system cancers

Advanced lung cancer patients get survival benefit with use of concurrent chemotherapy, proton therapy

Epigenetic dysregulation with age in normal breast tissue may contribute to cancer risk

UAlberta researchers find strong clues to underlying cause of HIV-associated neurocognitive disorders

Researchers show how hematopoietic stem cells detect and react to infections

Study: Response to combination immunotherapy in melanoma depends on proportion of immune cells

Researchers find new way to protect stem cells from inflammation during wound repair

Methicillin use not to blame for MRSA, say researchers

New report highlights beneficial effects of nonmedical interventions for people with dementia

Skin-applied microneedle patch boosts immunization to seasonal flu vaccine recipients, study finds

Researchers identify striking contrasts in how groups of neurons function during decision making

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