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Blocking telomerase increases cancer cells' sensitivity to radiation treatment

Shortening end caps on chromosomes in human cervical cancer cells disrupts DNA repair signaling, increases the cells' sensitivity to radiation treatment and kills them more quickly, according to a study in Cancer Prevention Research.

2 Dec 2011

New insight into why aminoglycoside antibiotics cause deafness

Peter Steyger's research on hearing is very personal. That's because Steyger - a research scientist with the Oregon Hearing Research Center at Oregon Health & Science University - is deaf. Now Steyger has published groundbreaking research that is as personal as it gets. The study gives scientists new insight into why a specific class of antibiotics causes deafness - the same class of antibiotics that caused Steyger's deafness as a child in England 48 years ago. The study was published this month in Scientific Reports, part of the Nature Publishing Group.

2 Dec 2011

ASH recognizes abstract presenters at 53rd annual meeting in San Diego

The American Society of Hematology (ASH) recognizes the following abstract presenters at the 53rd ASH annual meeting in San Diego, CA, with the highest scoring abstracts in the categories of undergraduate student, medical student, graduate student, resident physician, and postdoctoral fellow.

2 Dec 2011

John Theurer Cancer Center to present results of 31 studies at ASH 2011 meeting

The John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 best hospitals for cancer, will present research updates and clinical trial results of 31 cutting-edge studies at the 2011 American Society of Hematology (ASH) Annual Meeting in San Diego from December 10-13.

2 Dec 2011

Doctors underestimate worldwide burden of CPA, says public health expert

Researchers have discovered that over a million people worldwide diagnosed with TB go on to develop an incurable but manageable fungal infection which is usually left untreated because it is mistaken for a recurrence of the disease.

2 Dec 2011

Novel interventions promote CPAP use among people with OSA

People with obstructive sleep apnea are more likely to stick to prescribed treatment when a partner or parent is involved with their treatment, according to a team of sleep researchers.

2 Dec 2011

Benefits of exercise for breast cancer patients with lymphedema

Lymphedema, a chronic swelling condition common in breast cancer survivors, affects three million people in the U.S. In the past, most people believed that exercise might induce or worsen lymphedema. After reviewing the literature, University of Missouri researchers say the benefits of exercise outweigh the risks for breast cancer survivors and patients with lymphedema.

2 Dec 2011

Medicare to cover obesity screening, 'intensive behavioral therapy'

This coverage decision ensures that an estimated 30 percent of the 42 million people who participate in Medicare will be able to undertake physician-supervised weight-loss programs.

2 Dec 2011

New method reveals complete set of aberrant signaling pathways that give rise to cancers

One major obstacle in the fight against cancer is that anticancer drugs often affect normal cells in addition to tumor cells, resulting in significant side effects. Yet research into development of less harmful treatments geared toward the targeting of specific cancer-causing mechanisms is hampered by lack of knowledge of the molecular pathways that drive cancers in individual patients.

2 Dec 2011

Specific electromagnetic fields can block cancer cell growth

New evidence by University of Alabama at Birmingham researchers that specific electromagnetic fields can safely block the proliferation of cancer cells and tumor growth may help refine a new, targeted therapy without any collateral damage.

2 Dec 2011

NYU Langone establishes new LVAD Program for patients with advanced heart failure

The Cardiac & Vascular Institute at NYU Langone Medical Center has established its new LVAD Program. This surgical intervention program offers eligible, advanced heart failure patients implantation of the latest, lifesaving tool - a left ventricular assist device.

2 Dec 2011

Researchers discover how distant satellite cells could help repair damaged muscles

When a muscle is damaged, dormant adult stem cells called satellite cells are signaled to "wake up" and contribute to repairing the muscle. University of Missouri researchers recently found how even distant satellite cells could help with the repair, and are now learning how the stem cells travel within the tissue.

2 Dec 2011

Researchers identify cancer cell mitochondria as 'Achilles' heel' of tumor growth

Researchers at the Kimmel Cancer Center at Jefferson have identified cancer cell mitochondria as the unsuspecting powerhouse and "Achilles' heel" of tumor growth, opening up the door for new therapeutic targets in breast cancer and other tumor types.

2 Dec 2011

Cheaper test as effective as a more sophisticated test in guiding anti-retroviral drug treatment

A cheaper laboratory test that helps guide anti-retroviral drug treatment for people with HIV/AIDS may be just as effective as a more sophisticated test, a group of international researchers has found - a discovery that could be particularly important in rural Africa.

2 Dec 2011

Idera receives FDA notification to proceed with IMO-3100 Phase 2 clinical trial for psoriasis

Idera Pharmaceuticals, Inc. today announced the receipt of verbal notification from the Food and Drug Administration that the company may proceed with a Phase 2 clinical trial of IMO-3100 in patients with psoriasis based on a trial protocol submitted by the company in October 2011.

2 Dec 2011

Enrollment complete in Ceregene's CERE-120 Phase 2b trial for Parkinson's

Ceregene, Inc. reported today that it has completed enrollment in its Phase 2b trial of CERE-120, a gene therapy product expressing the neurturin (NRTN) gene for the treatment of Parkinson's disease.

1 Dec 2011

First Edition: December 1, 2011

In today's headlines, Republicans in Congress advance plan to charge wealthy beneficiaries more for Medicare in order to cover the costs of the proposaed payroll tax extension.

1 Dec 2011

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

The most poisonous substance on Earth - already used medically in small doses to treat certain nerve disorders and facial wrinkles - could be re-engineered for an expanded role in helping millions of people with rheumatoid arthritis, asthma, psoriasis and other diseases, scientists are reporting. Their study appears in ACS' journal Biochemistry.

1 Dec 2011

Compugen's Antibody Target Discovery Platform presented at 7th Annual European Antibody Congress

Speaking today at the plenary session of the 7th Annual European Antibody Congress in Geneva, Dr. Anat Cohen-Dayag, President and CEO of Compugen Ltd., presented Compugen's Antibody Target Discovery Platform, one of the Company's predictive discovery platforms for novel therapeutic targets.

1 Dec 2011

Researchers reveal ambivalent role of CXCL12/CXCR4 molecule in myocardial infarction

The chemokine CXCL12 acts as a chemical signal which mobilizes hematopoietic and other types of stem cells to leave the bone marrow and enter the circulation. Secretion of CXCL12 also guides these cells to sites at which the perfusion of tissue is sub-optimal due to localized obstruction of blood flow. These capabilities have made CXCL12 and its cognate receptor CXCR4 interesting candidates for therapies aimed at mitigating the effects of damage to the heart caused by myocardial infarction.

1 Dec 2011

Therapy News and Research

Blocking telomerase increases cancer cells' sensitivity to radiation treatment

New insight into why aminoglycoside antibiotics cause deafness

ASH recognizes abstract presenters at 53rd annual meeting in San Diego

John Theurer Cancer Center to present results of 31 studies at ASH 2011 meeting

Doctors underestimate worldwide burden of CPA, says public health expert

Novel interventions promote CPAP use among people with OSA

Benefits of exercise for breast cancer patients with lymphedema

Medicare to cover obesity screening, 'intensive behavioral therapy'

New method reveals complete set of aberrant signaling pathways that give rise to cancers

Specific electromagnetic fields can block cancer cell growth

NYU Langone establishes new LVAD Program for patients with advanced heart failure

Researchers discover how distant satellite cells could help repair damaged muscles

Researchers identify cancer cell mitochondria as 'Achilles' heel' of tumor growth

Cheaper test as effective as a more sophisticated test in guiding anti-retroviral drug treatment

Idera receives FDA notification to proceed with IMO-3100 Phase 2 clinical trial for psoriasis

Enrollment complete in Ceregene's CERE-120 Phase 2b trial for Parkinson's

First Edition: December 1, 2011

Botulism toxins could be re-engineered for treating RA, asthma, psoriasis

Compugen's Antibody Target Discovery Platform presented at 7th Annual European Antibody Congress

Researchers reveal ambivalent role of CXCL12/CXCR4 molecule in myocardial infarction

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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