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Cyclin E plays a crucial role in the formation of nerve connections

Scientists at Dana-Farber Cancer Institute and Harvard Medical School have found that a common cancer protein leads a second, totally different life in normal adult brain cells: It helps regulates memory formation and may be implicated in Alzheimer's disease.

23 Sep 2011

Three Johns Hopkins scientists receive NIH Director's New Innovator Awards

A pioneer in the field of epigenetics who has been spearheading the use of genome-wide technology for epigenetics research, a researcher who has revealed a weakness in the tuberculosis bacterium that makes it more susceptible to antibiotics, and a scientist who seeks to revolutionize new methods for toxicological testing to improve human health and reduce animal testing have received Director's Awards from the National Institutes of Health.

22 Sep 2011

UNC's new nanoparticle shows potential for cancer chemotherapy

A new type of nanoparticle developed in the laboratories at the University of North Carolina has shown potential for more effective delivery of chemotherapy to treat cancer.

21 Sep 2011

One in five cancer patients more likely to develop venous thromboembolism

An analysis of more than 30,000 cancer patients has shown that blood clots are a more common complication than doctors may realize, causing additional hospitalizations and driving up the cost of care, according to a study led by a Duke Cancer Institute researcher.

21 Sep 2011

New research has potential to alleviate side effects of cancer treatments

Beth Faiman MSN, CNP, a doctoral candidate at the Frances Payne Bolton School of Nursing at Case Western Reserve University, is studying whether an over-the-counter medication could ease chemotherapy side effects for people with blood and bone marrow cancers.

20 Sep 2011

Combination of lunasin and oxaliplatin prevents colon cancer from metastasis

A University of Illinois study reports a promising new weapon in treating metastatic colon cancer, particularly in patients who have developed resistance to chemotherapy.

20 Sep 2011

University of Groningen surgeons perform first fluorescence-guided ovarian cancer surgery

The first fluorescence-guided surgery on an ovarian cancer patient was performed using a cancer cell "homing device" and imaging agent created by a Purdue University researcher.

19 Sep 2011

CWRU receives NCI grant to advance treatment of gastrointestinal cancers

The National Cancer Institute has awarded $11.3 million to Case Western Reserve University School of Medicine to establish a center of excellence for research on gastrointestinal cancers.

19 Sep 2011

Case Western Reserve awarded $11.3M to establish gastrointestinal cancer research center

The National Cancer Institute has awarded $11.3 million to Case Western Reserve University School of Medicine to establish a center of excellence for research on gastrointestinal cancers. The funding designates the university as a Specialized Program of Research Excellence (SPORE) in Gastrointestinal (GI) Cancers - recognition extended to just one institution this year.

17 Sep 2011

Celecoxib inhibits GSK3 enzyme in lung cancer cells

Several clinical studies have shown that taking the anti-inflammatory drug celecoxib can reduce the risk of developing polyps that lead to colon cancers, at the cost of increasing the risk of heart disease. But what if this tradeoff was not necessary?

14 Sep 2011

BVES protein may play a role in colon cancer progression

A protein critical in heart development may also play a part in colon cancer progression. Research led by investigators from Vanderbilt-Ingram Cancer Center and the Vanderbilt Eye Institute suggests that the protein BVES (blood vessel endocardial substance) - which also is key in regulating corneal cells - may be a therapeutic target for halting colon cancer metastasis.

14 Sep 2011

Study finds high prevalence of lymph node evaluation for colon cancer

During the past two decades there has been a significant increase in the percentage of patients who have a high number of lymph nodes evaluated during colon cancer operations, but this improvement is not associated with an increase in the overall proportion of colon cancers that are node positive, according to a study in the September 14 issue of JAMA.

14 Sep 2011

Spices boost broccoli's power to fight cancer

Teaming fresh broccoli with a spicy food that contains the enzyme myrosinase significantly enhances each food's individual cancer-fighting power and ensures that absorption takes place in the upper part of the digestive system where you'll get the maximum health benefit, suggests a new University of Illinois study.

14 Sep 2011

Low-dose aspirin increases risk for GI bleeding

The risk of gastrointestinal (GI) bleeding needs to be considered when determining the potential preventive benefits associated with low-dose aspirin for cardiovascular disease and cancer.

12 Sep 2011

First Edition: September 7, 2011

"Publicly, consumer and patient advocates continue to cheer wildly for last year's health care law. Behind the scenes, however, some worry that they are losing a few key battles to the insurance and business communities.

7 Sep 2011

SYSU, ASU collaborate to develop early and predictive diagnostics for colorectal cancer

Arizona State University (ASU) and China's Sun Yat-Sen University (SYSU) have formalized a research collaboration aimed at developing early and predictive diagnostics to improve patient outcomes for colorectal cancer.

7 Sep 2011

Scientists identify human colon stem cells and grow them in lab-plates

Human colon stem cells have been identified and grown in a lab-plate for the first time. This achievement, made by researchers of the Colorectal Cancer Lab at the Institute for Research in Biomedicine and published in Nature Medicine, is a crucial advance towards regenerative medicine.

5 Sep 2011

Scientists discover highly conserved mechanism governing brain development

If you think today's political rhetoric is overheated, imagine what goes on inside a vertebrate embryo. There, two armies whose agendas are poles apart, engage in a battle with consequences much more dire than whether the economy will recover---- they are battling for whether you (or frogs or chickens) will have a forebrain.

3 Sep 2011

Researchers discover why tumors evolve

Like snakes, tumour cells shed their skin. Cancer is not a static disease but during its development the disease accumulates changes to evade natural defences adapting to new environmental circumstances, protecting against chemotherapy and radiotherapy and invading neighbouring organs, eventually causing metastasis.

3 Sep 2011

First report of alternative lengthening of telomeres in human cancer subtypes

The first report of the presence of alternative lengthening of telomeres (ALT) in cancers arising from the bladder, cervix, endometrium, esophagus, gallbladder, liver, and lung was published today in The American Journal of Pathology. The presence of ALT in carcinomas can be used as a diagnostic marker and has implications for the development of anti-cancer drug therapies.

3 Sep 2011