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Profectus begins Phase 1 clinical study of VesiculoVax-vectored Ebola virus vaccine

Profectus BioSciences, Inc., a clinical-stage vaccine company developing novel vaccines for the prevention and treatment of infectious diseases and the treatment of cancer, announced today the initiation of a Phase 1 clinical study of Profectus' VesiculoVax-vectored Ebola virus vaccine.

19 Jan 2016

RIKEN researchers discover how to reverse abnormal axonal development

Researchers at the RIKEN Brain Science Institute in Japan have discovered how to reverse the abnormal axonal development characteristic of CFEOM3, a congenital disease that affects the muscles that control eye movements.

19 Jan 2016

CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites.

19 Jan 2016

Researchers suggest ways to make TB drugs more efficacious against mutations

Biophysicists have discovered why the bacteria that cause tuberculosis (TB) are naturally somewhat resistant to antibiotics known as fluoroquinolones. Their findings, based on mapping the detailed three-dimensional structure of the drugs interacting with an essential enzyme in the TB germ, also reveal why some TB drugs are more potent than others and suggest how drug developers can make fluoroquinolones more efficacious against mutations that make the lung disease drug resistant.

19 Jan 2016

Researchers identify protein structure linked to pain and heat perception

Touch a hot stove, and your fingers will recoil in pain because your skin carries tiny temperature sensors that detect heat and send a message to your brain saying, "Ouch! That's hot! Let go!"

19 Jan 2016

NIST researchers simulate new method for fast, precise DNA sequencing

Researchers at the National Institute of Standards and Technology (NIST) have simulated a new concept for rapid, accurate gene sequencing by pulling a DNA molecule through a tiny, chemically activated hole in graphene--an ultrathin sheet of carbon atoms--and detecting changes in electrical current.

19 Jan 2016

Specialized oral nutrition supplement associated with 50% lower death rate in older patients

Results from a new clinical trial show that a specialized oral nutrition supplement was associated with a 50 percent lower death rate in older malnourished patients with a heart or lung disease 90 days following hospitalization.

18 Jan 2016

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

Pediatric researchers at UT Southwestern Medical Center have identified a key component of the pathogenesis of bronchopulmonary dysplasia (BPD), a devastating and sometimes fatal lung disease that affects premature infants. Their findings clarify what prompts the inflammatory response that results in BPD, which previously had been unclear.

18 Jan 2016

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Researchers at UT Southwestern Medical Center have identified a previously unrecognized small protein in cells of the human heart that plays a key role in heart muscle contraction. The protein is made from an RNA that was previously believed to be a blank or non-coding RNA, suggesting there may be many other small 'non-coding' segments that play important biological roles.

18 Jan 2016

Scientists find new way to re-engineer body’s immune system to target cancer

Scientists have demonstrated a new way of re-engineering the body’s immune system to target cancer, paving the way for a new generation of drugs, unprecedented in safety and effectiveness.

18 Jan 2016

Eating habits may influence sleep quality

A new study found that eating less fiber, more saturated fat and more sugar is associated with lighter, less restorative, and more disrupted sleep.

18 Jan 2016

Gene linked to autism lays groundwork for crucial brain structure during prenatal development

A gene linked to mental disorders helps lays the foundation for a crucial brain structure during prenatal development, according to Salk Institute research published January 14, 2016 in Cell Reports.

18 Jan 2016

Troponin T test provides possible one hour diagnosis of heart attack

Results from the TRAPID-AMI clinical study have been published online by the Annals of Emergency Medicine, confirming a novel approach for a more rapid diagnosis of heart attack in patients with acute chest pain.

From Roche Sequencing and Life Science 15 Jan 2016

High Performance UV Assay Microplates

Krystal UV quartz bottomed microplates from Porvair Sciences Ltd. are designed for high throughput applications which require excitation or detection wavelengths in the far UV region below 350nm.

From Porvair Sciences Limited 14 Jan 2016

Estrogen may protect women against flu

The female sex hormone estrogen has anti-viral effects against the influenza A virus, commonly known as the flu, a new study in American Journal of Physiology—Lung Cellular and Molecular Physiology reports.

13 Jan 2016

New UTMB study reveals link between traumatic brain injury and Alzheimer's disease

A new study from The University of Texas Medical Branch at Galveston fills an important gap in understanding the link between traumatic brain injury and neurodegenerative disorders such as Alzheimer's disease.

13 Jan 2016

Pulmonary neuroendocrine cells act like sensor to orchestrate immune response

An uncommon and little-studied type of cell in the lungs has been found to act like a sensor, linking the pulmonary and central nervous systems to regulate immune response in reaction to environmental cues.

13 Jan 2016

Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Lewy bodies had been considered to be a key element of pathogenesis for Parkinson's disease. Although structural analysis for Lewy bodies with an electron microscope had been performed, it had no secondary structural information of proteins, which is important for the development of drugs.

13 Jan 2016

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine.

13 Jan 2016

Cornell researchers identify potent cancer-killing proteins that can kill tumors in bloodstream

Cornell researchers have discovered potent cancer-killing proteins that can travel by white blood cells to kill tumors in the bloodstream of mice with metastatic prostate cancer. The breakthrough study will be published Feb. 10 as the cover article in the Journal of Controlled Release.

13 Jan 2016

G Protein News and Research

Profectus begins Phase 1 clinical study of VesiculoVax-vectored Ebola virus vaccine

RIKEN researchers discover how to reverse abnormal axonal development

CRISPR/Cas9 gene editing technique could be controlled using RNA-based drugs

Researchers suggest ways to make TB drugs more efficacious against mutations

Researchers identify protein structure linked to pain and heat perception

NIST researchers simulate new method for fast, precise DNA sequencing

Specialized oral nutrition supplement associated with 50% lower death rate in older patients

UT Southwestern pediatric researchers identify key trigger of neonatal lung disease

Findings offer potential new therapeutic target to boost strength of heart muscle contractions

Scientists find new way to re-engineer body’s immune system to target cancer

Eating habits may influence sleep quality

Gene linked to autism lays groundwork for crucial brain structure during prenatal development

Troponin T test provides possible one hour diagnosis of heart attack

High Performance UV Assay Microplates

Estrogen may protect women against flu

New UTMB study reveals link between traumatic brain injury and Alzheimer's disease

Pulmonary neuroendocrine cells act like sensor to orchestrate immune response

Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Cornell researchers identify potent cancer-killing proteins that can kill tumors in bloodstream

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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