Microscopy News and Research

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Researchers develop effective technique for studying high-arched palate using mouse model

Researchers from the laboratory of Paul Trainor, Ph.D., at the Stowers Institute of Medical Research have developed an effective and reliable technique for studying high-arched palate using a mouse model. The methodology could expand research into the genetic aspects of this craniofacial abnormality.

27 Feb 2016

Over-expression of heme oxygenase-1 enzyme protects the heart from doxorubicin damage

Life-threatening heart damage is an adverse side effect of the cancer drug doxorubicin, damage that also limits the use of newer chemotherapeutic agents such as trastuzumab and imatinib. The ability to protect the heart from these side effects would benefit patients, including cancer survivors who are at risk of developing heart damage years later, and it also could allow safer use of these drugs at higher doses.

26 Feb 2016

Moffitt researchers develop novel therapeutic strategy to keep resistant cells in check

Despite numerous advances in oncology since the War on Cancer began, many patients develop resistance to standard therapies and eventually relapse. Moffitt Cancer Center researchers hope to improve treatment outcomes with development of a novel therapeutic strategy, called adaptive therapy, which is based on evolutionary principals and aims to keep resistant cells in check by maintaining a population of chemo-sensitive cells.

25 Feb 2016

Study provides pathways to understand complex neurological disorders

Scientists have now described the engineering of a bright red fluorescent protein-based voltage indicator, providing pathways to understanding complex neurological disorders. Designated as FlicR1 (fluorescent indicator for voltage imaging red), these indicators enable imaging of the electrical activity of many genetically targeted neurons with high spatial and temporal resolution.

25 Feb 2016

Researchers reveal how stress conditions favor lytic reactivation of herpesviruses

Hiding their DNA genome inside the nucleus of the infected cells, the herpesviruses establish a lifelong infection in humans. Not well defined stress conditions are known to wake up these parasites from their dormancy - the latent phase - and reactivate the production of new viral progeny, eventually causing cell death by lysis - the lytic phase.

25 Feb 2016

MR Solutions introduces new 3D in vivo confocal microscope for preclinical research

MR Solutions’ new 3D in vivo confocal microscope for use in preclinical research provides a magnification range of up to 1000 times, allowing researchers to examine cellular details within a live small animal eliminating the need for a surgical biopsy - saving time and substantially reducing costs.

From MR Solutions 24 Feb 2016

UAB researchers use Malvern’s NanoSight NS300 system to figure out role of exosomes in disease transmission

Data measured using the NanoSight NS300 from Malvern Instruments is providing new insights into the role of exosomes in diseases such as cancer, arthritis, Alzheimer’s disease and cystic fibrosis, in pioneering research at the University of Alabama - Birmingham (UAB).

23 Feb 2016

Diabetes researchers develop novel technique to monitor insulin resistance

Diabetes researchers at Sweden's Karolinska Institutet have developed a novel technique that makes it possible to monitor insulin resistance in a non-invasive manner over time in mice. The new method, presented in the journal Scientific Reports, can be used to assess insulin resistance during progression and intervention of metabolic diseases.

22 Feb 2016

Newly developed intravital microscopy system proves safe for use in humans

A team of Roswell Park Cancer Institute researchers has developed and evaluated the first intravital microscopy system shown to be safe for use in humans. Writing in the journal Nature Communications, the scientists report that their proprietary technology enabled them, for the first time ever, to visualize tumor blood vessels in real time.

22 Feb 2016

Researchers identify new group of powerful Ebola-fighting antibodies

A research team that included scientists from The Scripps Research Institute has identified a new group of powerful antibodies to fight Ebola virus.

22 Feb 2016

New approach could open door to more personalized medications for diabetes patients

New research from the University of Copenhagen points to an entirely new approach for designing insulin-based pharmaceuticals. The approach could open the door for more personalized medications with fewer side effects for Type 1 Diabetes patients.

19 Feb 2016

Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar

Most proteins are involved in interactions with one or a few functional ligands, but some proteins, like light chain 8 (LC8), have numerous binding partners. LC8 interacts with more than 100 functionally different proteins, from viral proteins to motor proteins to proteins involved in cell division.

From Bruker BioSpin Group 18 Feb 2016

Streamlined medical device integration with new XLMii LED fiber optic light source

Excelitas Technologies® Corp., a global technology leader focused on delivering innovative, customized photonic solutions, today unveiled the new XLMii™ LED Fiber Optic Light Source for medical applications.

From Excelitas Technologies 17 Feb 2016

More powerful LED illumination for fluorescence microscopy

Excelitas Technologies® Corp., a global technology leader focused on delivering innovative, customized photonic solutions, introduces X-Cite® 120LEDBoost to replace their popular X-Cite 120LED broad-spectrum solution.

From Excelitas Technologies 17 Feb 2016

New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

With every heart attack, billions of cardiomyocytes, the contracting heart muscle cells that make the heart pump time after time over a lifetime, are lost which can lead to heart failure or injury. Stem cell-based replacement strategies could open new and much needed therapeutic avenues.

17 Feb 2016

Pioneering technique shows promise for new medical diagnostics, targeted drug delivery

Living systems rely on a dizzying variety of chemical reactions essential to development and survival. Most of these involve a specialized class of protein molecules--the enzymes.

12 Feb 2016

Simple physics may play key role in helping the body to fight infection

Simple physics may play a larger role than previously thought in helping control key bodily processes - such as how the body fights infection.

11 Feb 2016

Lamin nucleoskeleton disordered in Alzheimer's

Brain cell death in Alzheimer's disease is linked to disruption of a skeleton that surrounds the nucleus of the cells, a researcher in the School of Medicine at The University of Texas Health Science Center at San Antonio said.

5 Feb 2016

Rockefeller University study shows how herpes virus causes traffic jam in immune system pathway

With over half the U.S. population infected, most people are familiar with the pesky cold sore outbreaks caused by the herpes virus. The virus outsmarts the immune system by interfering with the process that normally allows immune cells to recognize and destroy foreign invaders. How exactly the herpes simplex 1 virus pulls off its nifty scheme has long been elusive to scientists.

4 Feb 2016

CMU joins $12 million research project to reverse-engineer the brain's secret algorithms

Carnegie Mellon University is embarking on a five-year, $12 million research effort to reverse-engineer the brain, seeking to unlock the secrets of neural circuitry and the brain's learning methods. Researchers will use these insights to make computers think more like humans.

4 Feb 2016

Microscopy News and Research

Researchers develop effective technique for studying high-arched palate using mouse model

Over-expression of heme oxygenase-1 enzyme protects the heart from doxorubicin damage

Moffitt researchers develop novel therapeutic strategy to keep resistant cells in check

Study provides pathways to understand complex neurological disorders

Researchers reveal how stress conditions favor lytic reactivation of herpesviruses

MR Solutions introduces new 3D in vivo confocal microscope for preclinical research

UAB researchers use Malvern’s NanoSight NS300 system to figure out role of exosomes in disease transmission

Diabetes researchers develop novel technique to monitor insulin resistance

Newly developed intravital microscopy system proves safe for use in humans

Researchers identify new group of powerful Ebola-fighting antibodies

New approach could open door to more personalized medications for diabetes patients

Revealing dynamic protein complexes with NMR: an interview with Elisar Barbar

Streamlined medical device integration with new XLMii LED fiber optic light source

More powerful LED illumination for fluorescence microscopy

New study could help explain critical shortcomings in stem cell-driven therapies for heart disease

Pioneering technique shows promise for new medical diagnostics, targeted drug delivery

Simple physics may play key role in helping the body to fight infection

Lamin nucleoskeleton disordered in Alzheimer's

Rockefeller University study shows how herpes virus causes traffic jam in immune system pathway

CMU joins $12 million research project to reverse-engineer the brain's secret algorithms

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