Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells. Prior to adoption as a medical therapeutic, safety concerns relating to off-target effects must be minimized to mitigate risks that may arise from the unintended action of this system at sites similar, but not identical, to the desired gene target site.

From Integrated DNA Technologies 10 Aug 2018

New discovery could pave way for improved leukemia treatment

Previous research has revealed that patients with acute myeloid leukemia who also have a particular mutation in a gene called NPM1 have a higher rate of remission with chemotherapy. About one-third of leukemia patients possess this favorable mutation, but until now, how it helps improve outcomes has remained unknown.

9 Aug 2018

New 3D-printed device could help spinal cord injury patients regain some function

Engineers and medical researchers at the University of Minnesota have teamed up to create a groundbreaking 3D-printed device that could someday help patients with long-term spinal cord injuries regain some function.

9 Aug 2018

Combination of arsenic and existing leukemia drug may combat cancer

Investigators have discovered that arsenic in combination with an existing leukemia drug work together to target a master cancer regulator.

9 Aug 2018

Scientists uncover reason for similarity between cells in malignant cancers and embryonic cells

Using just a microscope, Italian surgeon Francesco Durante was struck by the similarities between cells in the most malignant cancers and the embryonic cells of the organ in which the cancer originated.

9 Aug 2018

New drug delivery system delivers anticancer drugs that reduce tumor size

Cancer tissue cells are divided into two major groups: cancer cells and cancer stem cells. CSCs are related to cancer progression and dissemination, so it's necessary to eradicate CSCs in order to cure cancer.

9 Aug 2018

FDA approves drug for rare, hard-to-treat types of non-Hodgkin lymphoma

The U.S. Food and Drug Administration today approved Poteligeo (mogamulizumab-kpkc) injection for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides or Sézary syndrome after at least one prior systemic therapy.

8 Aug 2018

Scientists develop a way to deliver curcumin as an anti-cancer agent

Researchers have developed a way of delivering curcumin so that it can be effective as a therapeutic agent for cancer.

7 Aug 2018

Researchers find ways to render curcumin soluble and deliver it to infected tumors

In India and other countries in Southeast Asia, curcumin is often used as a spice in cooking, particularly chicken or fish. It is known for its therapeutic effect and as a way to kill germs present in raw meet.

7 Aug 2018

Clinical trial to use stem cell transplants for treating Crohn's disease

A clinical trial has begun which will use stem cell transplants to grow a new immune system for people with untreatable Crohn's disease - a painful and chronic intestinal disease which affects at least 115,000 people in the UK.

6 Aug 2018

Research uncovers new approach for expanding stem cells from umbilical cord blood

Researchers from the Stowers Institute for Medical Research and collaborators have identified a way to expand blood-forming, adult stem cells from human umbilical cord blood.

3 Aug 2018

Researchers develop 3D model of human placenta

The placenta is the organ connecting mother and embryo. Its main functions are the exchange of nutrients, gases and metabolic products and the production of hormones and other substances essential for embryonic development.

3 Aug 2018

New probe allows identification of cancer stem cells in situ

A fluorescent molecular probe that targets cancer stem cells has been developed at the University of Illinois at Urbana-Champaign.

2 Aug 2018

Pioneering research takes major step forward in the fight against cystic fibrosis

The fight against cystic fibrosis has taken a major step forward, with pioneering research by University of Adelaide scientists showing that cells causing the debilitating genetic disorder could be successfully replaced with healthy ones.

2 Aug 2018

Breakthrough in stem cell research could lead to cure for cystic fibrosis

Researchers have successfully proved that gene therapy can be used to convert adult stem cells into functioning lung cells for the treatment of cystic fibrosis

2 Aug 2018

Researchers discover key piece for slowing colorectal cancer subtype

Inhibiting the Jagged 1 protein in mice prevents the proliferation and growth of colon and rectal tumors. What is more, this approach to the disease permits the removal of existing tumors.

2 Aug 2018

3D-printed implants appear to guide regrowth of missing bone in lab animals

Chemically coated, ceramic implants successfully guided the regrowth of missing bone in lab animals while "steadily dissolving," researchers report.

2 Aug 2018

Researchers discover new, rare type of cell in the human airway

In separate studies published online in Nature on Aug. 1, two independent research teams report the discovery of a new, rare type of cell in the human airway.

2 Aug 2018