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Common misconception about penicillin allergies

It's time for your primary care check-up, and the doctor asks you to list any known drug allergies. "Penicillin," you say immediately, although you can't remember actually taking the drug or having a reaction to it—it was your parents who said so. According to a Texas A&M Health Science Center allergist, many people who believe they're allergic to this antibiotic may not actually be allergic at all.

5 May 2016

Children infected with Cryptosporidium parasite more likely to suffer from stunted growth

Children infected even just once with a certain type of waterborne parasite are nearly three times as likely to suffer from moderate or severe stunted growth by the age of two than those who are not - regardless of whether their infection made them feel sick, new Johns Hopkins Bloomberg School of Public Health-led research suggests.

5 May 2016

Long-term Warfarin use may increase dementia rates in AF patients

A new study of more than 10,000 patients treated long term with the blood thinner, Warfarin, reveals higher rates of dementia for patients with atrial fibrillation versus non-AF patients

5 May 2016

Older adults become more sensitive to pain, study shows

When older relatives complain about their pains, show a little empathy, because new research suggests that as we age, we may all become more sensitive to pain. A small, preliminary University of Florida Health study has suggested for the first time that inflammation may occur more quickly and at a higher magnitude -- and stays around longer -- when older adults experience pain versus when younger adults experience pain.

5 May 2016

Study shows short-term statin treatment does not benefit heart surgery patients

Giving daily doses of statins for a few days before and after heart surgery does not prevent heart muscle damage or the development of atrial fibrillation (AF), according to an international clinical trial led by the University of Oxford and funded by the British Heart Foundation.

5 May 2016

ITJ researchers develop new hydrating beverage for athletes

Jiquiquilpan's Institute of Technology in Mexico developed a hydrating beverage for athletes that is based on agave's fructans, that not only supplies the adequate water levels to the organisms, but also offers other benefits such as dietetic fiber.

5 May 2016

Enzyme previously thought beneficial could pose threat to developing embryos

A pair of Oklahoma Medical Research Foundation scientists have discovered that an enzyme previously thought only to be beneficial could, in fact, pose significant danger to developing embryos. The new research could have implications not only for prenatal development but also for treating lymphedema and liver damage resulting from acetaminophen overdose.

5 May 2016

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

Researchers at University of California San Diego School of Medicine have shown that ozanimod (RPC1063), a novel drug molecule, is moderately effective in the treatment of ulcerative colitis. Results of the Phase II clinical trial will appear in the May 5 issue of the New England Journal of Medicine.

5 May 2016

New robotic arm could safely perform soft tissue surgery, reduce human errors

Not even the surest surgeon's hand is quite as steady and consistent as a robotic arm built of metal and plastic, programmed to perform the same motions over and over. So could it handle the slippery stuff of soft tissues during a surgery?

5 May 2016

Innovative bone marrow-on-a-chip microdevice holds promise for developing improved radiation countermeasures

Engineered bone marrow grown in a novel microfluidic chip device responds to damaging radiation exposure followed by treatment with compounds that aid in blood cell recovery in a way that mimics living bone marrow.

5 May 2016

LifeBridge Health study to explore potential benefits of wireless heart monitoring system

The LifeBridge Health Cardiovascular Institute has launched a pilot study to evaluate the potential benefits of a wireless heart monitoring system for patients with moderate to severe heart failure. The system tracks weight, blood pressure and other measures, and automatically sends the information to doctors and staff at the Cardiovascular Institute. The study is looking at whether this approach, designed to be simple and easy-to-use, can result in better outcomes for patients with heart failure.

5 May 2016

High-fructose diet during pregnancy may affect fetal growth

Consuming a high-fructose diet during pregnancy may cause defects in the placenta and restrict fetal growth, potentially increasing a baby's risk for metabolic health problems later in life, according to research in mice and people by a team at Washington University School of Medicine in St. Louis.

5 May 2016

Detailed digital models of human organs could bring substantial benefits to clinical trials

Computer simulations of disease processes and detailed digital models of our organs could provide more accurate monitoring and outcome measurements for clinical trials, according to research being presented in Sheffield today.

5 May 2016

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

To make a good framework for filling in missing bone, mix at least 30 percent pulverized natural bone with some special man-made plastic and create the needed shape with a 3-D printer. That's the recipe for success reported by researchers at The Johns Hopkins University in a paper published April 18 online in ACS Biomaterials Science & Engineering.

5 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

Candida yeast infections more common in men with schizophrenia or bipolar disorder

In a study prompted in part by suggestions from people with mental illness, Johns Hopkins researchers found that a history of Candida yeast infections was more common in a group of men with schizophrenia or bipolar disorder than in those without these disorders, and that women with schizophrenia or bipolar disorder who tested positive for Candida performed worse on a standard memory test than women with schizophrenia or bipolar disorder who had no evidence of past infection.

4 May 2016

Study evaluates effects of corticosteroids along with anti-tuberculosis drugs in tuberculous meningitis

The Cochrane Infectious Diseases Group have carried out a review update to evaluate the effects of corticosteroids being used alongside anti-tuberculosis medication to treat people suffering from tuberculous meningitis.

4 May 2016

New 3D-printed talus replacement surgery to treat avascular necrosis provides life-changing experience

The talus is the part ankle that allows the foot to move in all different directions. High impact injuries like falls, or traffic accidents can cause the talus bone to be fractured, and a high percentage of these injuries result in avascular necrosis (AVN)—the death of the bone. In a first-of-its-kind procedure using 3D printing technology, internationally renowned orthopedic surgeon Dr. Mark Myerson, Director, The Institute for Foot and Ankle Reconstruction at Mercy Medical Center, explains how a talus replacement, tailored to the patient's specific dimensions, can result in a "life-changing experience" for the patient.

4 May 2016

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

Researchers and doctors at Uppsala University, along with Swedish and international collaboration partners, have found gene variants that predict the risk of a serious adverse reaction to drugs used for the treatment of hyperthyroidism. The results are published in The Lancet Diabetes & Endocrinology.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

Blood News and Research

Common misconception about penicillin allergies

Children infected with Cryptosporidium parasite more likely to suffer from stunted growth

Long-term Warfarin use may increase dementia rates in AF patients

Older adults become more sensitive to pain, study shows

Study shows short-term statin treatment does not benefit heart surgery patients

ITJ researchers develop new hydrating beverage for athletes

Enzyme previously thought beneficial could pose threat to developing embryos

Experimental drug ozanimod moderately effective in treatment of ulcerative colitis

New robotic arm could safely perform soft tissue surgery, reduce human errors

Innovative bone marrow-on-a-chip microdevice holds promise for developing improved radiation countermeasures

LifeBridge Health study to explore potential benefits of wireless heart monitoring system

High-fructose diet during pregnancy may affect fetal growth

Detailed digital models of human organs could bring substantial benefits to clinical trials

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

Bayer-new phase 3 liver cancer data

Candida yeast infections more common in men with schizophrenia or bipolar disorder

Study evaluates effects of corticosteroids along with anti-tuberculosis drugs in tuberculous meningitis

New 3D-printed talus replacement surgery to treat avascular necrosis provides life-changing experience

Researchers find gene variants that predict adverse effects of hyperthyroidism drugs

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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