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Positive data from XENTION's XEN-D0103 phase 1 trial on AF

XENTION LTD, the Cambridge-based biopharmaceutical company specialising in the discovery and development of ion channel-modulating drugs, reported positive data today from a phase 1 trial of XEN-D0103 administered orally.

20 Mar 2012

CSIS report examines HIV prevention, care among people who inject drugs in Ukraine

A new report, titled "Injection Drug Use in Ukraine" and published by the Center for Strategic & International Studies (CSIS), examines the challenges of providing HIV prevention and care services in the country, particularly to people who inject drugs (PWID), who accounted for "nearly 50 percent of new HIV infections registered in 2010," according to the CSIS website.

20 Mar 2012

FHCRC research represents potential breakthrough in treatment of pancreas cancer

Pancreas cancer tumors spread quickly and are notoriously resistant to treatment, making them among the deadliest of malignancies. Their resistance to chemotherapy stems in part from a unique biological barrier the tumor builds around itself. Now scientists at Fred Hutchinson Cancer Research Center have found a way to break through that defense, and their research represents a potential breakthrough in the treatment of pancreas cancer.

20 Mar 2012

Hedgehog and mTOR pathway are active in esophageal cancer

Identification of a non-traditional pathway for spiriting a cancer-promoting protein into the cell nucleus points to a possible combination therapy for esophageal cancer and indicates a mechanism of resistance for new drugs that attack the Hedgehog pathway.

20 Mar 2012

Infection preventionists, healthcare epidemiologists play key roles in promoting antimicrobial stewardship

Infection preventionists and healthcare epidemiologists play key roles in promoting effective antimicrobial stewardship in collaboration with other health professionals, according to a joint position paper published today by the Association for Professionals in Infection Control and Epidemiology (APIC) and the Society for Healthcare Epidemiology of America (SHEA) in their respective peer-review journals, the American Journal of Infection Control and Infection Control and Hospital Epidemiology.

20 Mar 2012

CJC publishes updated atrial fibrillation guidelines

The Canadian Journal of Cardiology has published a focused update to the Canadian Cardiovascular Society's atrial fibrillation guidelines.

20 Mar 2012

New information on efficacy of CLA in treating Crohn's disease

The Nutritional Immunology and Molecular Medicine Laboratory (NIMML) research team at Virginia Tech has discovered important new information on the efficacy of conjugated linoleic acid (CLA) in treating Crohn's disease, a form of inflammatory bowel disease (IBD). CLA is a naturally occurring acid found in meat and dairy products known for its anti-cancer and immune modulatory properties.

20 Mar 2012

TB Alliance launches new combination drug trial

In an ambitious effort to stem the dangerous tide of tuberculosis (TB) and deadly drug-resistant TB around the world, TB Alliance today announced that it has launched a first-of-its-kind clinical trial to test a novel drug combination – in both patients who have TB and those who have multidrug-resistant TB (MDR-TB).

19 Mar 2012

Gilenya - pill for relapsing-remitting multiple sclerosis recommended by NICE

The National Institute for Health and Clinical Excellence (Nice) issued new draft guidance recommending fingolimod (brand name Gilenya) on the NHS for some patients with a form of MS. The new drug can help reduce the number of relapses in adults with highly active relapsing-remitting multiple sclerosis (RRMS), which is characterized by periods when symptoms worsen and then improve.

19 Mar 2012

Technique developed to identify rogue clustering proteins in brain diseases

Australian researchers have developed a novel technique that tracks proteins “behaving badly” and may have found a way that leads to new treatments for brain disease. The team believes the discovery could help in the development of drugs to treat diseases such as Alzheimer's, Parkinson's and Huntington's.

19 Mar 2012

Common infections could become deadly with increase in antibiotic resistance, WHO's Chan says

As more bacteria become resistant to antibiotics, "common infections could become deadly, according to" WHO Director-General Margaret Chan, who spoke on Wednesday at a conference titled "Combating Antimicrobial Resistance: Time for Action" in Copenhagen, ABC News reports.

19 Mar 2012

Novel technique rapidly identifies and tracks location of diseased proteins inside cells

A research team led by the University of Melbourne, Australia, has developed a novel technique that tracks diseased proteins behaving badly by forming clusters in brain diseases such as Huntington's and Alzheimer's.

19 Mar 2012

New health care law helps 5.1M seniors and people with disabilities save $3.2B on prescription drugs

As the second anniversary of the Affordable Care Act approaches, new data shows that more than 5.1 million seniors and people with disabilities on Medicare saved over $3.2 billion on prescription drugs because of the new health care law, Kathleen Sebelius, Secretary of the U.S. Department of Health and Human Services (HHS), announced today while at the St. Louis Community College at Forest Park.

19 Mar 2012

Medicare plan will be central to Ryan GOP budget

House Budget Committee Chairman Paul Ryan, R-Wis., is set to unveil a new budget plan on Tuesday. Both Democrats and Republicans are poised to revive the pitched debate over controversial proposals related to the Medicare programs.

19 Mar 2012

Ampio completes partial planned interim review in Optina trial for diabetic macular edema

Ampio Pharmaceuticals, Inc., a biopharmaceutical company conducting clinical trials on its three lead drugs (Zertane completed two phase III studies, Ampion-completed proof of concept studies and Optina), licensing distribution of these drugs and engaged in further drug development, today announced that it completed the planned interim review of the first 50% of patients enrolled in the Optina trial for diabetic macular edema.

19 Mar 2012

Gender gap in medication management

There is a wide gender divide when it comes to how men and women are prescribed and adhere to their medications. According to a new study, while women use more prescription drugs than men, they are less likely to be prescribed drugs according to clinical guidelines and are not as good about adhering to the medications they are prescribed.

19 Mar 2012

Biomedical Systems launches wireless ambulatory ECG monitoring system for management of AF

Biomedical Systems, a global provider of cardiac diagnostic services and products, has introduced the TruVue® Wireless Ambulatory ECG Monitoring System for the diagnosis and management of atrial fibrillation and other complex cardiac arrhythmia.

19 Mar 2012

First Edition: March 19, 2012

Today's headlines reflect the anticipation and anxiety that surrounds the Supreme Court's upcoming health law oral arguments.

19 Mar 2012

Largest ever academic-industry research project to find new drugs for ASD

An international consortium of scientists, led by Roche, King's College London, and Autism Speaks, is collaborating on one of the largest ever academic-industry research projects to find new methods for the development of drugs for autism spectrum disorder.

From CSL Ltd 19 Mar 2012

RBCC's new agreement with n3D could help develop stem-cell therapies

As global demand for innovative new stem-cell therapies grows by the day, Rainbow BioSciences' new agreement with n3D Biosciences could help to bring these therapies to market faster than ever before.

19 Mar 2012

Drugs News and Research

Positive data from XENTION's XEN-D0103 phase 1 trial on AF

CSIS report examines HIV prevention, care among people who inject drugs in Ukraine

FHCRC research represents potential breakthrough in treatment of pancreas cancer

Hedgehog and mTOR pathway are active in esophageal cancer

Infection preventionists, healthcare epidemiologists play key roles in promoting antimicrobial stewardship

CJC publishes updated atrial fibrillation guidelines

New information on efficacy of CLA in treating Crohn's disease

TB Alliance launches new combination drug trial

Gilenya - pill for relapsing-remitting multiple sclerosis recommended by NICE

Technique developed to identify rogue clustering proteins in brain diseases

Common infections could become deadly with increase in antibiotic resistance, WHO's Chan says

Novel technique rapidly identifies and tracks location of diseased proteins inside cells

New health care law helps 5.1M seniors and people with disabilities save $3.2B on prescription drugs

Medicare plan will be central to Ryan GOP budget

Ampio completes partial planned interim review in Optina trial for diabetic macular edema

Gender gap in medication management

Biomedical Systems launches wireless ambulatory ECG monitoring system for management of AF

First Edition: March 19, 2012

Largest ever academic-industry research project to find new drugs for ASD

RBCC's new agreement with n3D could help develop stem-cell therapies

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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