Malignant News and Research

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Gold nanoparticles help detect lung cancer in exhaled breath

The metabolism of lung cancer patients is different than the metabolism of healthy people. And so the molecules that make up cancer patients' exhaled breath are different too.

17 Nov 2011

VHIO, MGHCC sign tumor biomarker agreement

The President of the BBVA Foundation, Francisco Gonz-lez, Jose Baselga, Chief of Hematology/Oncology at Massachusetts General Hospital Cancer Center (MGHCC), and Andr-s de Kelety, Managing Director at the Vall d'Hebr-n Institute of Oncology (VHIO) in Barcelona, yesterday signed the agreement creating the BBVA Foundation Tumor Biomarkers Research Program.

17 Nov 2011

Human pluripotent stem cells rely heavily on glycolysis to drive their metabolic activities

Human pluripotent stem cells, which can develop into any cell type in the body, rely heavily on glycolysis, or sugar fermentation, to drive their metabolic activities.

16 Nov 2011

Combination of antipsychotic and antidepressant drugs may increase risk of CV mortality

People taking anti-psychotic drugs and anti-depressant drugs have a much higher risk of dying during an acute coronary event of a fatal arrhythmia than the rest of the population, finds a Finnish study published in the European Heart Journal.

16 Nov 2011

Study confirms link between CMV and mucoepidermoid carcinoma

An important new study from the Laboratory for Developmental Genetics at USC has confirmed cytomegalovirus (CMV) as a cause of the most common salivary gland cancers. CMV joins a group of fewer than 10 identified oncoviruses - cancer-causing viruses - including HPV.

16 Nov 2011

Radon exposure may increase risk of non-melanoma skin cancer

A new study published this week suggests that a link may exist between radon exposure and non-melanoma skin cancer.

15 Nov 2011

Scientists identify factors that lead to concomitant tumor resistance

Scientists are another step closer to understanding what drives tumor metastasis, as laboratory models suggest there are factors inside tumors that can slow their own growth.

14 Nov 2011

Novel gene mutation may increase risk of inherited and sporadic cases of MM

A major international study has identified a novel gene mutation that appears to increase the risk of both inherited and sporadic cases of malignant melanoma, the most deadly form of skin cancer.

14 Nov 2011

New studies could fundamentally change medical treatment of liver cancer

Scientists at the Helmholtz Zentrum München have played a major role in two studies that could fundamentally change the medical treatment of liver cancer. Doctors are now able to determine the degree of aggressiveness of the tumour in the early stages and can thus devise an individualised treatment plan.

10 Nov 2011

FDA clears IDEV 6Fr SUPERA VERITAS Transhepatic Biliary Stent System

IDEV Technologies, Incorporated, today announced the FDA has granted 510(k) clearance for the company's 6 French (6Fr) SUPERA VERITAS Transhepatic Biliary Stent System.

10 Nov 2011

Fascin protein may play a critical transformation role in TGF beta mediated tumor metastasis

A protein called "fascin" appears to play a critical transformation role in TGF beta mediated tumor metastasis, say researchers at Moffitt Cancer Center in Tampa, Fla., who published a study in a recent issue of the Journal of Biological Chemistry.

10 Nov 2011

Infinity third quarter total revenue increases marginally to $23.3 million

Infinity Pharmaceuticals, Inc. today highlighted its recent clinical and business progress and announced its third quarter 2011 financial results.

9 Nov 2011

Viagra may improve antitumor immunity in people with melanoma

At first it sounds like good news: The body's own immune system gets active in almost every cancer - however, not necessarily for the benefit of the patient. "We distinguish between two different types of immune response," says Professor Dr. Viktor Umansky, immunologist at DKFZ and University Medical Center Mannheim. "On the one hand, cells of the immune system specifically attack tumor cells.

9 Nov 2011

Celldex Therapeutics initiates CDX-1127 Phase 1 study in malignant solid tumors

Celldex Therapeutics, Inc. today announced initiation of a Phase 1 study of its therapeutic human antibody candidate, CDX-1127, in patients with selected malignant solid tumors or hematologic cancers.

8 Nov 2011

EpiCept reports net loss of $5.4 million for third quarter 2011

EpiCept Corporation today announced operating and financial results for the three and nine months ended September 30, 2011, and provided an update with respect to the Company's key business initiatives.

8 Nov 2011

PKM2 enzyme has important non-metabolic functions in cancer formation

The embryonic enzyme pyruvate kinase M2 (PKM2) has a well-established role in metabolism and is highly expressed in human cancers. Now, a team led by researchers at the University of Texas MD Anderson Cancer Center reports in advance online publication of the journal Nature that PKM2 has important non-metabolic functions in cancer formation.

7 Nov 2011

Link between use of anti-TNF therapy and malignant melanoma in RA patients

According to research presented this week at the American College of Rheumatology Annual Scientific Meeting in Chicago, people taking anti-tumor necrosis factor therapies to treat rheumatoid arthritis have a higher risk of developing malignant melanoma.

7 Nov 2011

New technologies could aid in malignant melanoma diagnosis and therapy

Because the incidence of malignant melanoma is rising faster than any other cancer in the U.S., researchers at Moffitt Cancer Center in Tampa, Fla., and colleagues at Tampa-based Intezyne Technologies, Inc., Western Carolina University and the University of Arizona are working overtime to develop new technologies to aid in both malignant melanoma diagnosis and therapy.

4 Nov 2011

Asuragen announces data from microRNA biomarker study on pancreatic cancer

Asuragen, Inc. announced today that data from a collaborative study with Johns Hopkins regarding microRNA biomarkers for use on pancreatic cyst fluid specimens was presented at the American Pancreatic Association Annual Meeting being held November 2-5, 2011 in Chicago.

4 Nov 2011

Early diagnosis of large intestine cancer could be feasible in the long term

Itxaro Perez, a biochemist at the University of the Basque Country (UPV/EHU), has contributed in such a way that, in the long term, the early diagnosis of cancer of the large intestine could be feasible.

4 Nov 2011