Microscope News and Research

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Novel type of communication between nerve cells in the brain discovered

The findings may have relevance for the prevention and treatment of epilepsy, and possibly in the exploration of other aspects of brain functions, from creative thought processes to mental illnesses such as schizophrenia.

17 Jul 2007

Nodal status is best predictor of outcome after neoadjuvant therapy for esophageal cancer

The number of lymph nodes that contain evidence of cancer is the best predictor of the effectiveness of adding chemotherapy and radiation to a treatment plan prior to surgery in individuals with oesophageal cancer, according to a study published last month in the Annals of Surgery.

16 Jul 2007

DNA' s double helix shape explained

Researchers at Duke University's Pratt School of Engineering have uncovered a missing link in scientists' understanding of the physical forces that give DNA its famous double helix shape.

13 Jul 2007

NanoSIMS instrument clarifies nutrient cycle

Scientists at the University of Southern California have applied a nanoscale imaging method to a biological system, helping to clear up an old puzzle of the global carbon and nitrogen cycle.

9 Jul 2007

Support for chromosomal theory of cancer found in cancers' development of drug resistance

Thirty-six years into the war on cancer, scientists have not only failed to come up with a cure, but most of the newer drugs suffer from the same problems as those available in the pre-war days: serious toxicity, limited effectiveness and eventual resistance.

28 Jun 2007

New type of mouse embryonic stem cell discovered

Scientists have discovered a new type of mouse embryonic stem cell that is the closest counterpart yet to human embryonic stem (ES) cells, the National Institutes of Health (NIH) have announced.

28 Jun 2007

Scientists discover role of ataxia telangiectasia mutated protein in DNA repair

Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), and Integrative Bioinformatics Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the body's ability to repair damaged DNA.

28 Jun 2007

New genetic test advances detection and diagnosis of muscular dystrophy

A new genetic test targeting the most common types of muscular dystrophy--those caused by mutations in the dystrophin gene--is far quicker with greater accuracy and sensitivity than existing tests.

28 Jun 2007

CARS microscopy reveals clues to myelin damage

Researchers have discovered that calcium ions could play a crucial role in multiple sclerosis by activating enzymes that degrade the fatty sheath that insulates nerve fibers.

28 Jun 2007

FDA approves rapid test for malaria

The U.S. Food and Drug Administration has cleared for marketing the Binax NOW Malaria Test, the first authorized U.S. rapid test for malaria, a mosquito-borne disease caused by a parasite. The test is intended for laboratory use.

27 Jun 2007

Stanford researchers get scoop on baby poop!

Researchers at the Stanford University School of Medicine are as interested in a baby's poop as doting parents are, and for good reason.

26 Jun 2007

DNA repair proteins monitored at double-strand break

St. Jude investigators recently had a molecule's eye view of the human cell's DNA repair kit as it assembled on a double-strand break to link together the broken ends.

23 Jun 2007

Microfluidic chip for cancer diagnosis

For the first time an important diagnostic test for cancer has been miniaturized and automated onto a microfluidic chip by a team of University of Alberta researchers in Edmonton, Canada.

20 Jun 2007

Scientists discover proteins in blood that accurately identify colon cancer and precancerous polyps

Initial studies of the proteins, CCSA-3 and CCSA-4, suggest they could be used to develop a blood test to identify at-risk individuals.

19 Jun 2007

Quantum dots outline brain tumors for surgical removal

Although surgical removal of a tumor can be the most effective way of treating brain cancer, neurosurgeons are often faced with the dilemma of determining the exact border between a tumor and the healthy tissue that surrounds it.

14 Jun 2007

Scientists observe cell migration

Johns Hopkins researchers have found a way to directly observe cell migration -- in real time and in living tissue. In a report in Developmental Cell, the scientists say their advance could lead to strategies for controlling both normal growth and the spread of cancer, processes that depend on the programmed, organized movement of cells across space.

14 Jun 2007

HIV uses pathways to infect cells

Like hobos on a train, HIV, the virus that causes AIDS, uses a pre-existing transport system to leave one infected cell and infect new ones, Hopkins scientists have discovered.

8 Jun 2007

Flaxseed halts prostate tumor growth

Flaxseed, an edible seed that is rich in omega 3-fatty acids and fiber-related compounds known as lignans, is effective in halting prostate tumor growth, according to a study led by Duke University Medical Center researchers.

5 Jun 2007

Diagnosing skin cancers with laser-based system

In an early step toward nonsurgical screening for malignant skin cancers, Duke University chemists have demonstrated a laser-based system that can capture three-dimensional images of the chemical and structural changes under way beneath the surface of human skin.

5 Jun 2007

Scientists have captured on video the intracellular version of a postal delivery service

Reporting in the journal Biochemical and Biophysical Research Communications (BBRC), bioengineering researchers at UC San Diego published videos of a key message-carrying protein called paxillin moving abruptly from hubs of communication and transportation activity on the cell surface toward the nucleus.

3 Jun 2007