Mouse Model News and Research

RSS

Three studies describe advances toward development of antibodies to stop HIV

A trio of studies being published today in the journals Science and Cell describes advances toward the development of an HIV vaccine. The three study teams all demonstrated techniques for stimulating animal cells to produce antibodies that either could stop HIV from infecting human cells in the laboratory or had the potential to evolve into such antibodies.

19 Jun 2015

Researchers explore the science of exosomes in heart repair

A little more than a decade ago, researchers discovered that all cells secrete tiny communications modules jammed with an entire work crew of messages for other cells. Today, a team of researchers, led by stem cell researcher Raj Kishore, PhD, Director of the Stem Cell Therapy Program at the Center for Translational Medicine at Temple University School of Medicine, is harnessing the communications vesicles excreted by stem cells and using them to induce the damaged heart to repair itself.

19 Jun 2015

Experimental AIDS vaccine candidate stimulates immune system to block infection in animal model

New research led by scientists at The Scripps Research Institute, International AIDS Vaccine Initiative and The Rockefeller University shows that an experimental vaccine candidate can stimulate the immune system to block HIV infection in mice.

18 Jun 2015

Ruhr-Universität Bochum scientists develop mouse model to investigate SCA6

Scientists at the Ruhr-Universität Bochum established a mouse model for the human disease SCA6. SCA6 is characterised by movement deficits and caused by similar genetic alterations as Chorea Huntington. The mouse model will be used to investigate the disease mechanisms.

17 Jun 2015

New therapy for osteoporosis may be in the pipeline

Researchers from The Scripps Research Institute (TSRI), Florida, have reported a novel therapeutic approach that could promote the formation of new bone cells in people suffering from bone loss.

12 Jun 2015

Researchers show how a new drug speeds tissue regeneration in animal models

The concept sounds like the stuff of science fiction: take a pill, and suddenly new tissues grow to replace damaged ones. Researchers at Case Western Reserve and UT Southwestern Medical Center this week announced that they have taken significant steps toward turning this once-improbable idea into a vivid reality.

12 Jun 2015

Study seeks to determine environmental factors that protect against asthma, allergies

Researchers in the University of Arizona's BIO5 Institute have entered into a collaboration with Johnson & Johnson Consumer & Personal Products and Janssen Biotech Inc. to leverage foundational discovery research aimed at determining environmental factors that underlie asthma and allergies.

12 Jun 2015

Daily dose of aspirin effective at blocking breast tumor growth

"Take two aspirin and call me in the morning" has been the punchline for countless jokes. Could it also be good advice for cancer patients? A lab study to appear in the July 2015 issue of Laboratory Investigation found that a daily dose of aspirin was effective at blocking breast tumor growth. Previous studies have already shown a similar effect on colon, gastrointestinal, prostate, and other cancers.

12 Jun 2015

Common antibiotic azithromycin effectively kills many multidrug-resistant bacteria

Contrary to current medical dogma, researchers at University of California, San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences report that the common antibiotic azithromycin kills many multidrug-resistant bacteria very effectively — when tested under conditions that closely resemble the human body and its natural antimicrobial factors.

11 Jun 2015

Study on how maternal proteins help regulate initial cell divisions during early development

Researchers in the University of Georgia's Regenerative Bioscience Center are visually capturing the first process of chromosome alignment and separation at the beginning of mouse development. The findings could lead to answers to questions concerning the mechanisms leading to birth defects and chromosome instability in cancer cells.

10 Jun 2015

New research shows that low glycemic index diets reduce autism symptoms in mice

Bread, cereal and other sugary processed foods cause rapid spikes and subsequent crashes in blood sugar. In contrast, diets made up of vegetables, fruits and whole grains are healthier, in part because they take longer to digest and keep us more even-keeled.

9 Jun 2015

Stemedica receives FDA's IND approval for itMSC Phase IIa clinical trial to treat Alzheimer's disease

Stemedica Cell Technologies, Inc. received the FDA's investigational new drug (IND) approval for a United States-based, Phase IIa clinical study using its allogeneic stem-cell therapy to treat subjects with mild to moderate dementia due to Alzheimer's disease (AD), the sixth leading cause of death in the United States.

9 Jun 2015

Frankfurt researchers decode molecular details that provide better understanding of neurodegenerative diseases

Quality control is important - this is not only applicable to industrial production but also true for all life processes. However, whereas an enterprise can start a large-scale recall in case of any doubt, defects in the quality control systems of cells are often fatal.

9 Jun 2015

Researchers identify immune system marker that drives therapy-resistant prostate cancer

You are a patient who has just been treated for a serious illness but neither you nor your doctor knows how likely it is that you -- in comparison with other patients -- will actually be helped by the treatment. This is often the situation with prostate cancer, one of the deadliest and most highly prevalent cancers. While hormone therapy can help, patient responses vary widely, and it's still unclear why some types of prostate cancer seem to be resistant to the therapy.

5 Jun 2015

Oxygen regulatory pathway can act to trigger tissue regeneration in mice

A study led by Ellen Heber-Katz, PhD, of the Lankenau Institute for Medical Research, part of Main Line Health, shows that a primordial form of energy production that still exists in mammals can be harnessed to achieve spontaneous tissue regeneration in mice, without the need for added stem cells.

4 Jun 2015

Feinberg physiology professor named recipient of 2015 AES Seed Grant

Today the American Epilepsy Society announced Anis Contractor, Ph.D., Associate Professor of Physiology at Northwestern University, Feinberg School of Medicine, as the recipient of a 2015 AES Seed Grant. Dr. Contractor's proposed research seeks to address a fundamental question about cellular and circuit level excitability in the mouse model of Dravet Syndrome.

3 Jun 2015

March of Dimes funds studies that explore factors, mechanisms involved in placental malaria

Malaria infection during pregnancy poses serious risks to women and infants. The March of Dimes Foundation, an American organization that works to improve pregnancy and baby health, has now funded Carlos Penha-Goncalves' laboratory, at the Instituto Gulbenkian de Ciencia (IGC, Portugal), for their studies on factors and mechanisms involved in placental malaria. This is the first time that this American Foundation funds research from a Portuguese Institution.

3 Jun 2015

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Scientists at the University of California, San Diego and the Massachusetts Institute of Technology have described a new method for detecting liver cancer metastases in mice. The approach uses over-the-counter probiotics genetically programmed to produce signals easily detectable in urine when liver cancer metastases are present.

2 Jun 2015

Researchers identify previously unknown gene mutation that causes achromatopsia

People with achromatopsia, an inherited eye disorder, see the world literally in black and white. Worse yet, their extreme sensitivity to light makes them nearly blind in bright sunlight. Now, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health System have identified a previously unknown gene mutation that underlies this disorder.

2 Jun 2015

Previously unknown gene mutation linked to inherited eye disorder, achromatopsia

2 Jun 2015

Mouse Model News and Research

Three studies describe advances toward development of antibodies to stop HIV

Researchers explore the science of exosomes in heart repair

Experimental AIDS vaccine candidate stimulates immune system to block infection in animal model

Ruhr-Universität Bochum scientists develop mouse model to investigate SCA6

New therapy for osteoporosis may be in the pipeline

Researchers show how a new drug speeds tissue regeneration in animal models

Study seeks to determine environmental factors that protect against asthma, allergies

Daily dose of aspirin effective at blocking breast tumor growth

Common antibiotic azithromycin effectively kills many multidrug-resistant bacteria

Study on how maternal proteins help regulate initial cell divisions during early development

New research shows that low glycemic index diets reduce autism symptoms in mice

Stemedica receives FDA's IND approval for itMSC Phase IIa clinical trial to treat Alzheimer's disease

Frankfurt researchers decode molecular details that provide better understanding of neurodegenerative diseases

Researchers identify immune system marker that drives therapy-resistant prostate cancer

Oxygen regulatory pathway can act to trigger tissue regeneration in mice

Feinberg physiology professor named recipient of 2015 AES Seed Grant

March of Dimes funds studies that explore factors, mechanisms involved in placental malaria

Genetically-programmed probiotics could help detect liver cancer metastases early-on

Researchers identify previously unknown gene mutation that causes achromatopsia

Previously unknown gene mutation linked to inherited eye disorder, achromatopsia

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News