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First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

A study published in the journal eLife made all the possible mutations in the amyloid beta peptide and tested how they influence its aggregation into plaques, a pathological hallmark of Alzheimer's disease.

9 Mar 2021

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

Schizophrenia is a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. Researchers have long searched for genetic influences in the disease, but genetic mutations have been identified in only a small fraction--fewer than a quarter--of sequenced patients.

9 Mar 2021

CBD ameliorates cognitive function in experimental model of familial Alzheimer's

A two-week course of high doses of CBD helps restore the function of two proteins key to reducing the accumulation of beta-amyloid plaque, a hallmark of Alzheimer's disease, and improves cognition in an experimental model of early onset familial Alzheimer's, investigators report.

9 Mar 2021

New brain sensor could transform our understanding of Alzheimer’s

Scientists at the University of Virginia School of Medicine have developed a tool to monitor communications within the brain in a way never before possible, and it has already offered an explanation for why Alzheimer's drugs have limited effectiveness and why patients get much worse after going off of them.

9 Mar 2021

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands.

9 Mar 2021

Parkinson’s UK, University of Sheffield to develop new Parkinson’s drug

Parkinson's UK, the largest charitable funder of Parkinson's research in Europe, is investing up to £1.2 million into a pioneering one-year project in partnership with the University of Sheffield.

9 Mar 2021

Compounds in green and black tea relax blood vessels by activating ion channel proteins

A new study from the University of California, Irvine shows that compounds in both green and black tea relax blood vessels by activating ion channel proteins in the blood vessel wall.

8 Mar 2021

Researchers reprogram glial cells into new neurons to heal spinal cord injury

Researchers at Indiana University School of Medicine have successfully reprogrammed a glial cell type in the central nervous system into new neurons to promote recovery after spinal cord injury--revealing an untapped potential to leverage the cell for regenerative medicine.

8 Mar 2021

Researchers find new way to prevent attention deficits associated with Fragile X syndrome

Mount Sinai Researchers find a new way to prevent attention deficits associated with Fragile X, a leading genetic cause of autism, in an animal model.

8 Mar 2021

Researchers create new nerve cells, spur recovery after spinal cord injury

Using genetic engineering, researchers at UT Southwestern and Indiana University have reprogrammed scar-forming cells in mouse spinal cords to create new nerve cells, spurring recovery after spinal cord injury.

8 Mar 2021

Scientists seek to enhance artificial intelligence by integrating brain cells

With a new grant from the U.S. Army, a team of scientists will seek to enhance artificial intelligence by integrating brain cells called astrocytes.

5 Mar 2021

New evidence supports the use of antisense oligonucleotides as feasible therapeutic strategy for MDS

Many cognitive neurodevelopmental disorders are a result of too many or too few copies of certain genes or chromosomes.

5 Mar 2021

Study reveals close link between Parkinson's disease and certain immune cells in the blood

Parkinson's disease has always been considered a brain disorder. However, new research reveals a close link between the disease and certain immune cells in the blood.

4 Mar 2021

Smoking cessation drug shows potential to treat Parkinson's disease in females

Texas A&M University College of Medicine ressearchers have recently discovered that cytisine -- a smoking cessation drug commonly used in Europe -- reduces the loss of dopamine neurons in females. These findings provide potential evidence for the use of the drug to treat Parkinson's disease or stop its progression in women.

4 Mar 2021

Structural insights into glycine transporter open new avenues to find effective psychiatric drugs

Glycine can stimulate or inhibit neurons in the brain, thereby controlling complex functions. Unraveling the three-dimensional structure of the glycine transporter, researchers have now come a big step closer to understanding the regulation of glycine in the brain.

4 Mar 2021

Researchers identify the trigger of key cellular change in amyotrophic lateral sclerosis

Scientists at the Francis Crick Institute and UCL have identified the trigger of a key cellular change in amyotrophic lateral sclerosis (ALS), a type of motor neurons disease.

4 Mar 2021

New transcriptome‐based aging clock reads the biological age of an organism

Using the model organism Caenorhabditis elegans, researchers at the University of Cologne have developed an 'aging clock' that reads the biological age of an organism directly from its gene expression, the transcriptome.

3 Mar 2021

$High-resolution imaging, 3D computer modeling reveal the fractal nature of neurons$

High-resolution imaging, 3D computer modeling reveal the fractal nature of neurons

High-resolution imaging and 3D computer modeling show that the dendrites of neurons weave through space in a way that balances their need to connect to other neurons with the costs of doing so.

3 Mar 2021

Yale researchers identify multiple genes involved in suppression of axon regeneration

When central nervous system cells in the brain and spine are damaged by disease or injury, they fail to regenerate, limiting the body's ability to recover.

2 Mar 2021

Novel drug for preventing Alzheimer's disease found to be safe and effective in animals

Researchers at the University of California San Diego School of Medicine and Massachusetts General Hospital have identified a new drug that could prevent Alzheimer's disease by modulating, rather than inhibiting, a key enzyme involved in forming amyloid plaques in the brain.

2 Mar 2021

Neurons News and Research

First complete atlas of how mutations affect the formation of amyloid plaques in Alzheimer’s disease

Somatic gene mutations in brain cells could contribute to schizophrenia pathology

CBD ameliorates cognitive function in experimental model of familial Alzheimer's

New brain sensor could transform our understanding of Alzheimer’s

Scientists develop RNA-based therapeutic strategy for Charcot-Marie Tooth disease

Parkinson’s UK, University of Sheffield to develop new Parkinson’s drug

Compounds in green and black tea relax blood vessels by activating ion channel proteins

Researchers reprogram glial cells into new neurons to heal spinal cord injury

Researchers find new way to prevent attention deficits associated with Fragile X syndrome

Researchers create new nerve cells, spur recovery after spinal cord injury

Scientists seek to enhance artificial intelligence by integrating brain cells

New evidence supports the use of antisense oligonucleotides as feasible therapeutic strategy for MDS

Study reveals close link between Parkinson's disease and certain immune cells in the blood

Smoking cessation drug shows potential to treat Parkinson's disease in females

Structural insights into glycine transporter open new avenues to find effective psychiatric drugs

Researchers identify the trigger of key cellular change in amyotrophic lateral sclerosis

New transcriptome‐based aging clock reads the biological age of an organism

High-resolution imaging, 3D computer modeling reveal the fractal nature of neurons

Yale researchers identify multiple genes involved in suppression of axon regeneration

Novel drug for preventing Alzheimer's disease found to be safe and effective in animals

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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