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Commonly used mouthwash increases lactate-producing bacteria that lower saliva pH

The first study looking at the effect of chlorhexidine mouthwash on the entire oral microbiome has found its use significantly increases the abundance of lactate-producing bacteria that lower saliva pH, and may increase the risk of tooth damage.

24 Mar 2020

Using cannabinoids for management of acute pain

A new systematic review and meta-analysis showed a small but significant reduction in subjective pain scores for cannabinoid treatment compared to placebo in patients experiencing acute pain.

23 Mar 2020

Wasan lab develops novel oral formulation to treat systemic fungal infections

The Wasan Laboratory in the Faculty of Pharmaceutical Sciences at the University of British Columbia in partnership with iCo Therapeutics Inc. (Vancouver BC, Canada) have developed a novel oral formulation of Amphotericin B to treat systemic fungal and parasitic infections.

23 Mar 2020

Melinjo seed extract may improve obesity and diabetes

In Southeast Asia, the fruit, flowers, and leaves of Indonesia's "Melinjo" tree are traditional foods.

23 Mar 2020

Stem cells establish contacts with nerves in tissue regeneration and cancer progression

Researchers at the University of Zurich show that different stem cell populations are innervated in distinct ways.

23 Mar 2020

Cumulative doses of oral steroids associated with increased hypertension

Cumulative doses of oral steroids in patients with chronic inflammatory diseases are associated with increased hypertension (blood pressure) for those who take them regularly, found new research in CMAJ.

23 Mar 2020

Plasma monitoring of EGFR mutations in NSCLC may help predict resistance to tyrosine kinase inhibitors

Oncotarget Volume 11, Issue 11 reported that at clinical progression, 64 EGFR T790M plasma positive patients were subjected to second line-treatment with osimertinib and strictly monitored during the first month of therapy.

22 Mar 2020

CARB-X awards $2.86M to develop novel oral antibiotic to treat drug-resistant gonorrhea

Up to $2.86M has been awarded to a research team including Penn State scientists to develop a new oral antibiotic to treat multidrug-resistant gonorrhea, a sexually transmitted disease caused by bacteria that have developed resistance to all but one existing antibiotic.

20 Mar 2020

Individuals should to 'drink to thirst' to manage exercise-related hyponatremia

Hyponatremia is a condition of low sodium concentration in the blood. Prolonged overhydration during exercise is the primary cause of all forms of exercise-associated hyponatremia (EAH) and should be avoided.

18 Mar 2020

Study examines psychological impacts of frontier wars on Aboriginal people

Hundreds of Aboriginal men who became native mounted police in colonial Australia carried a significant burden of responsibility for law and order for white settlers in Queensland and other settlements.

18 Mar 2020

Damaging the tumor blood vessels could be new strategy to treat oral cancer

Researchers at Okayama University have recently published a study in Cells in which they reduced the size of oral cancer tumors by damaging the blood vessels surrounding the tumor cells.

17 Mar 2020

Bacteria multiply and grow into biofilms like settlers form cities

Microbiologists have long adopted the language of human settlement to describe how bacteria live and grow: They "invade" and "colonize." Relations dwelling in close proximity are "colonies."

13 Mar 2020

What does COVID-19 do to the body?

The novel coronavirus SARS-CoV-2, also known as 2019-nCoV, is the virus that causes COVID-19, and that is spreading throughout the world is causing panic in almost all countries. With a death rate ranging from 1% to 2% in young patients but about 5%-8% in elderly and sick patients, it is capable of ravaging multiple organ systems in the human body.

12 Mar 2020

Cream infused with microscopic STAR particles could facilitate better treatment of skin diseases

Skin diseases affect half of the world's population, but many treatments are not effective, require frequent injections, or cause significant side effects.

10 Mar 2020

Researchers succeed in creating a common language to describe pain

For the first time, an international collaboration of researchers have succeeded in creating a complete overview of all pain conditions in the face, mouth and jaw and classifying them in the same way.

10 Mar 2020

Dental shock: Six pulled teeth and one unexpected bill

The ache in three of Kathy McCracken's teeth started almost four years ago. It was hard for her to chew and swallow. She was sensitive to both hot and cold food.

10 Mar 2020

PrEP drug levels found to lower among pregnant African adolescent girls and young women

Among African adolescent girls and young women who took HIV pre-exposure prophylaxis (PrEP) daily, levels of the PrEP drug tenofovir were more than 30% lower in those who were pregnant than in those who had recently given birth.

9 Mar 2020

Rotavirus vaccination not linked to type 1 diabetes mellitus risk

Rotavirus infection is thought to be a risk factor for type 1 diabetes mellitus (T1DM). The role played by live attenuated rotavirus vaccination in the risk of this condition in children is, therefore, an area of active research. A new study published in the journal JAMA Pediatrics in March 2020 debunks this concern.

9 Mar 2020

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Could the response to cancer immunotherapy depend on bacteria that originate in the gut and travel to the tumor?

7 Mar 2020

Gastrointestinal manifestations and fecal-oral transmission of novel coronavirus

The world is bracing for the impact of the novel coronavirus, COVID-19, which has now spread to over 30 countries, infecting more than 80,000 people with over 2,600 deaths globally. A better understanding of how this virus is transmitted is key to preventing its spread.

5 Mar 2020

Oral News and Research

Commonly used mouthwash increases lactate-producing bacteria that lower saliva pH

Using cannabinoids for management of acute pain

Wasan lab develops novel oral formulation to treat systemic fungal infections

Melinjo seed extract may improve obesity and diabetes

Stem cells establish contacts with nerves in tissue regeneration and cancer progression

Cumulative doses of oral steroids associated with increased hypertension

Plasma monitoring of EGFR mutations in NSCLC may help predict resistance to tyrosine kinase inhibitors

CARB-X awards $2.86M to develop novel oral antibiotic to treat drug-resistant gonorrhea

Individuals should to 'drink to thirst' to manage exercise-related hyponatremia

Study examines psychological impacts of frontier wars on Aboriginal people

Damaging the tumor blood vessels could be new strategy to treat oral cancer

Bacteria multiply and grow into biofilms like settlers form cities

What does COVID-19 do to the body?

Cream infused with microscopic STAR particles could facilitate better treatment of skin diseases

Researchers succeed in creating a common language to describe pain

Dental shock: Six pulled teeth and one unexpected bill

PrEP drug levels found to lower among pregnant African adolescent girls and young women

Rotavirus vaccination not linked to type 1 diabetes mellitus risk

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Gastrointestinal manifestations and fecal-oral transmission of novel coronavirus

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