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Low-dose estrogen effective for metastatic breast cancer

When estrogen-lowering drugs no longer control metastatic breast cancer, the opposite strategy might work. Raising estrogen levels benefited 30 percent of women whose metastatic breast cancer no longer responded to standard anti-estrogen treatment, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

19 Aug 2009

Novel treatment reduces swollen livers

Viruses need living cells for replication and production of virus progeny. Thus far, antiviral therapy primarily targets viral factors but often induces therapy resistance. New improved therapies attempt to targets cellular factors that are essential for viral replication.

16 Aug 2009

Drug design: palladium catalyst used to attach fluorine atom to aromatic compounds

A team of MIT chemists has devised a new way to add fluorine to a variety of compounds used in many drugs and agricultural chemicals, an advance that could offer more flexibility and potential cost-savings in designing new drugs.

13 Aug 2009

Traditional Chinese acupuncture affects the brain's long-term ability to regulate pain

Acupuncture has been used in East-Asian medicine for thousands of years to treat pain, possibly by activating the body's natural painkillers. But how it works at the cellular level is largely unknown.

10 Aug 2009

Cutting-edge imaging research aims to map brain injuries

In the first study of its kind, researchers at Saint Louis University are recruiting patients for a clinical trial that will use cutting-edge imaging equipment to map the brain injuries of combat veterans and civilians, aiming to better understand the nature of their injuries.

5 Aug 2009

Clinical trial to test gene therapy for Alzheimer’s disease

Researchers at the Shiley-Marcos Alzheimer's Disease Research Center at the University of California San Diego are about to launch a Phase 2 clinical trial to test a gene therapy treatment for Alzheimer’s disease (AD) called CERE-110.

4 Aug 2009

Coronary calcium scoring may predict heart attack risk

Researchers may be able to predict future severe cardiac events in patients with known, stable coronary artery disease (CAD) using coronary calcium scoring, according to a study published in the online edition of Radiology.

28 Jul 2009

Compact gamma camera for prostate cancer imaging

The U.S. Department of Energy's Brookhaven National Laboratory and Hybridyne Imaging Technologies, Inc., of Toronto, Canada, have won a 2009 R&D 100 Award for developing a compact gamma camera for high-resolution imaging of prostate cancer.

23 Jul 2009

New brain visualization technology enables removal of fist-sized tumor

A new technology involving the fusion of four different types of images into a 3-D map of a patient's brain has helped University of Cincinnati (UC) specialists successfully remove a fist-sized tumor from the brain of an Indiana woman.

14 Jul 2009

Brain imaging (MRI/PET) bring us closer to earlier detection of Alzheimer's

Changes in the brain measured with MRI and PET scans, combined with memory tests and detection of risk proteins in body fluids, may lead to earlier and more accurate diagnosis of Alzheimer's, according to new research reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna.

14 Jul 2009

Young black women prone to gain more unhealthy abdominal fat than Hispanics, study shows

Black women ages 20 to 29 have increased amounts of unhealthy abdominal and visceral fat than Hispanic women the same age, and young women of both age groups have more as compared to their elders, according to researchers from Wake Forest University Baptist Medical Center and colleagues.

1 Jul 2009

Computer-guided nanoparticle therapy destroys tumors

Gold nanoshells are among the most promising new nanoscale therapeutics being developed to kill tumors, acting as antennas that turn light energy into heat that cooks cancer to death. Now, a multi-institutional research team has shown that polymer-coated gold nanorods one-up their spherical counterparts, with a single dose completely destroying all tumors in a nonhuman animal model of human cancer.

28 Jun 2009

Cryo-electron tomography shows immature HIV in 3D

Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional reconstruction of HIV (Human Immunodeficiency Virus), which shows the structure of the immature form of the virus at unprecedented detail. Immature HIV is a precursor of the infectious virus, which can cause AIDS.

23 Jun 2009

Biomarker in urine for appendicitis

Appendicitis is the most common childhood surgical emergency, but the diagnosis can be challenging, especially in children, often leading to either unnecessary surgery in children without appendicitis, or a ruptured appendix and serious complications when the condition is missed.

23 Jun 2009