Laboratory News and Research

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Discovery may pave way for immunotherapies for prostate cancer

Using a common chemotherapy agent, researchers at UCLA's Jonsson Cancer Center and the Department of Pathology and Laboratory Medicine found a way to move an important biomarker expressed in prostate cancer, shaking it loose from one location in a cell – where it could not be accessed by blood – to another, easier to target area.

11 May 2005

New laser technology for more precise cancer treatments

Tom Cowan’s team is thinking smaller, but with big impact. Particle accelerators are a key research tool in a high energy physicist’s arsenal, but they take up a lot of space - miles and miles of it. But at the University of Nevada, Reno, smaller is better.

10 May 2005

Research offers new molecular approaches to therapies for the most deadly cancers

Researchers at Wake Forest University Baptist Medical Center have found promising new molecular targets and treatment approaches for some of the most malignant brain tumors.

10 May 2005

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

Scientists at St. Jude Children’s Research Hospital have joined with colleagues at several other institutions to develop a laboratory model of the human immune system. This model will allow scientists to study ways for improving the results of hematopoietic stem cell (HSC) transplantation without putting patients at risk.

10 May 2005

African Americans and Caucasians viewing African American faces display extremely similar changes in the activity of brain structures that respond to emotional events

The changes occur in the amygdala, a region of the brain that serves as an "alarm" to activate a cascade of other biological systems to protect the body in times of danger, said Matthew D. Lieberman, assistant professor of psychology at UCLA and lead author of the study.

9 May 2005

Clues about how alcoholic behavior is “switched” on

As part of an ongoing effort to understand the biochemical basis of alcohol abuse, scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have published two studies on how modulating receptors for dopamine - a chemical “signaler” in the brain’s reward circuits - affects drinking behavior in mice and rats.

9 May 2005

Metabolic syndrome costing four times that for all other patients

It is well known that hypertension, diabetes, and obesity are each taking a toll on Americans' health, but according to a new analysis, metabolic syndrome, a condition characterized by a combination of these and/or other risk factors, is fast becoming one of the nation's costliest health concerns.

9 May 2005

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

The first study identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. Researchers found that a little-known protein called Fra-1 was effective in controlling vascular endothelial growth factor D, a factor that promotes the growth of new blood vessels in most malignant brain tumors.

8 May 2005

Stem-cell breakthrough gives new hope for IVF treatments

In a scientific first, human eggs have been grown in the laboratory using stem cells scraped from the surface of women's ovaries and the development raises the possibility of delaying menopause and providing a limitless source of donor eggs for in vitro fertilisation treatments and embryonic stem cell research.

5 May 2005

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

By deciphering the ingenious mechanism used by a particular enzyme to modify bacterial chromosome chemistry, scientists have come a step closer to designing a new kind of drug that could stop virulent bacterial infections in their tracks. Their research will be published in the May 6 issue of the journal Cell.

5 May 2005

Drug safety in the doctor’s office - nearly half of patients have lapses in monitoring

According to research published in the Journal of General Internal Medicine, only slightly more than half of patients taking chronic medications received the recommended laboratory tests to monitor drug side effects.

5 May 2005

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

A powerful laboratory technique used by fruit fly geneticists for more than a decade is now available to scientists studying genes and diseases in mice.

5 May 2005

Cancer hijacks normal wound-healing processes

Scientists have known for the last decade that a link exists between wound healing and cancer. For instance, in a 1994 experiment at the Lawrence Berkeley National Laboratory, chickens infected with a cancer virus developed tumors in areas of their body that had undergone wounding or scarring, while no tumors developed in infected areas that had not suffered wounding.

5 May 2005

Pretty kids get the best deal all round

Disturbing new evidence from researchers at the University of Alberta in Canada, which is hard to believe, suggests that parents take better care of pretty children than they do of ugly ones.

4 May 2005

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Researchers at the University of Pennsylvania School of Medicine have identified in normal cells that a common metabolic enzyme, which acts as a rheostat of cellular conditions, also controls cell replication.

4 May 2005

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Two infant boys whose bodies were overloaded with excess fluid have led UCSF pediatricians to the discovery of a new genetic disease. In the process, they have discovered a rare type of mutation where different substitutions in a single amino acid cause two different, opposite genetic disorders.

4 May 2005

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

A new vaccine designed at The Rockefeller University boosted a type of fast-responding immune system cell called the natural killer T (NKT) cell in patients with advanced cancer. The study surprised researchers by revealing the ability of these NKT cells to spur other, slower-responding immune cells to go to work.

4 May 2005

Mutated gene causes serious heart disease in newborns

The research group of professor Manfred Kilimann at the Department of Cell and Molecular Biology has elucidated the genetic cause of a severe heart disease in newborn children. This result will be published in the June issue of the American Journal of Human Genetics this week.

3 May 2005

Scientists use tobacco plants to create antibodies against tumor cells

Scientists at Jefferson Medical College are using tobacco plants to produce monoclonal antibodies – tiny guided protein missiles – that can target and hunt down cancer cells. The plants promise to provide a cheaper, faster method of producing anticancer antibodies, raising hopes that the technology can one day be used in humans.

3 May 2005

Mother of all treatments could cure baldness, and banish stretch marks!

A new discovery by scientists might just be the 'mother of all treatments' in promising a treatment for balding men, women with stretchmarks and anyone who has gum disease.

3 May 2005

Laboratory News and Research

Discovery may pave way for immunotherapies for prostate cancer

New laser technology for more precise cancer treatments

Research offers new molecular approaches to therapies for the most deadly cancers

Laboratory model of immune system overcomes ethical constraints on studies of hematopoietic stem cells in humans

African Americans and Caucasians viewing African American faces display extremely similar changes in the activity of brain structures that respond to emotional events

Clues about how alcoholic behavior is “switched” on

Metabolic syndrome costing four times that for all other patients

Promising new molecular targets and treatment approaches for some of the most malignant brain tumors

Stem-cell breakthrough gives new hope for IVF treatments

Scientists take aim at virulent bacteria by decoding machinery of key control enzyme

Drug safety in the doctor’s office - nearly half of patients have lapses in monitoring

Mosaic Analysis with Double Markers (MADM) - A powerful new tool to study diseases and genetics

Cancer hijacks normal wound-healing processes

Pretty kids get the best deal all round

Penn researchers demonstrate that a metabolic enzyme works through the tumor-suppressor protein p53 to control cellular replication

Nephrogenic Syndrome of Inappropriate Antidiuresis - a new genetic disease

Vaccine developed at Rockefeller University boosts natural killer T cells in patients with cancer

Mutated gene causes serious heart disease in newborns

Scientists use tobacco plants to create antibodies against tumor cells

Mother of all treatments could cure baldness, and banish stretch marks!

A guide to density measurement excellence eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo