Protein C News and Research

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Study finds frequent anaemia in patients with chronic respiratory failure

A study of nearly 600 patients with severe non-inflammatory respiratory disease has found that a significant percentage also suffered from anaemia, according to the April issue of IJCP, the International Journal of Clinical Practice.

31 Mar 2011

Two new studies on cancer

Last year, a research team at the University of North Carolina at Chapel Hill discovered one way the protein Tet 1 helps stem cells keep their pluripotency-the unique ability to become any cell type in the body.

31 Mar 2011

Basic Yellow 1 dye extends lifespan in healthy nematodes, slows Alzheimer's disease-like pathology in worms

Basic Yellow 1, a dye used in neuroscience laboratories around the world to detect damaged protein in Alzheimer's disease, is a wonder drug for nematode worms. In a study appearing in the March 30, online edition of Nature, the dye, also known as Thioflavin T, (ThT) extended lifespan in healthy nematode worms by more than 50 percent and slowed the disease process in worms bred to mimic aspects of Alzheimer's.

31 Mar 2011

Candy consumption can help reduce weight and risk of CVD

Good news for candy and chocolate lovers: they tend to weigh less, have lower body mass indices and waist circumferences, and have decreased levels of risk factors for cardiovascular disease and metabolic syndrome, according to a new study published in Nutrition Research.

31 Mar 2011

First transdisciplinary research center dedicated to identify causes of premature birth

The March of Dimes and Stanford University School of Medicine today launched the nation's first transdisciplinary research center dedicated to identifying the causes of premature birth. Prematurity is the number one reason for newborn death in the United States today, yet in nearly half of the cases of premature birth, there is no identifiable cause.

31 Mar 2011

Immunotec, NSU to conduct new research study in children with autism

Nova Southeastern University and the dietary supplement company Immunotec announced today that they will conduct a new research study to determine the effects of a supplement to improve behaviors in children with Autism Spectrum Disorder.

31 Mar 2011

Higher protein diets associated with greater feelings of fullness during weight loss

Dieters trying to stick to their diets may want to look no further than lean protein, according to two studies published in the prestigious journal Obesity. Including protein such as lean pork in three daily meals could reduce late-night desires to eat, increase feelings of fullness and decrease distracting thoughts about food, according to the research.

31 Mar 2011

Essential protein linked to TNF induced inflammation

SCIENTISTS have discovered an essential protein that controls inflammation induced by 'tumour necrosis factor' (TNF) - an important part of the body's defences against infection and a driver of cancer-associated inflammation, according to research published in Nature today (Wednesday).

31 Mar 2011

SLN to present Atu027 Phase I study data against solid cancer at ASCO Annual Meeting

Silence Therapeutics plc a leading global RNA interference therapeutics company, announces that interim data from its ongoing Phase I clinical study of Atu027, the Company's lead internal therapeutic candidate, have been accepted for poster presentation at the 2011 American Society of Clinical Oncology Annual Meeting.

30 Mar 2011

Attacks by specific type of immune cells cause inflammations of heart muscle

Scientists of the German Cancer Research Center, jointly with colleagues in the United States, have found out that inflammations of the heart muscle are caused by attacks of a specific type of immune cells. These immune cells attack the body's own tissue because during their maturation they did not have the chance to develop tolerance against a protein that is only found in the heart muscle.

30 Mar 2011

Multiple drugs bonded to 'transport vehicle' bypass healthy cells to attack breast cancer from inside

Researchers at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute have employed a strategy using a mouse model to target important mechanisms inside the most challenging breast cancer cells. Earlier studies at Cedars-Sinai found a similar approach effective in attacking malignant brain tumor targets.

30 Mar 2011

Eya1 phosphatase controls fate of embryonic lung epithelial stem cells

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have provided the first evidence that Eya1 protein phosphatase is a crucial regulator of the development of embryonic lung epithelial stem cells.

30 Mar 2011

Positive results from Vertex VX-770 Phase 3 trial against CF

Vertex Pharmaceuticals Incorporated today announced positive results from a 24-week analysis of the ongoing Phase 3 ENVISION study of VX-770, an oral medicine in development that targets the defective protein that causes cystic fibrosis.

30 Mar 2011

Labcyte launches 1536-well tissue-culture treated microplate for cell-based screening

Labcyte Inc. today launched a new 1536-well tissue-culture treated microplate for cell-based screening and discovery applications. By enabling cell culture directly in a high-density microplate, this new product expands cell-based assay miniaturization capabilities, such as direct PCR from cell cultures.

30 Mar 2011

Oral antioxidant formulation before medical imaging may minimize cell damage

A unique formulation of antioxidants taken orally before imaging with ionizing radiation minimizes cell damage, noted researchers at the Society of Interventional Radiology's 36th Annual Scientific Meeting in Chicago, Ill.

30 Mar 2011

New lung cancer drug starts human trials

A new drug for lung cancer is being tried by researchers at Oxford. The treatment, which halts the growth of cancer cells, is being trialed on those patients who have stopped responding to chemotherapy. The trial is one of the first to go ahead at the Oxford Cancer Research Centre.

29 Mar 2011

Protein aggregation plays a significant role in cancer

Protein aggregation, generally associated with Alzheimer's and mad cow disease, turns out to play a significant role in cancer. In a paper published in Nature Chemical Biology, Frederic Rousseau and Joost Schymkowitz of VIB, K.U.Leuven and Vrije Universiteit Brussel describe that certain mutations of p53, an important tumor suppressor, cause the protein to misfold in a way that the proteins start to aggregate.

29 Mar 2011

Scientists to discover new estrogen receptor-signaling networks for breast cancer treatment

The quandary of breast cancer in women is deep: the female hormone, estrogen, is considered to be a quasi-fuel for developing breast cancer.

29 Mar 2011

Researchers find patients with Alzheimer's have lower glucose utilization in brain

Researchers at Mount Sinai School of Medicine have found that patients with Alzheimer's disease have lower glucose utilization in the brain than those with normal cognitive function, and that those decreased levels may be detectable approximately 20 years prior to the first symptoms of Alzheimer's disease.

29 Mar 2011

International Phase II trial to study LY2181308 efficacy in patients with lung cancer

Cancer Research UK scientists in Oxford are trialling an experimental drug to treat lung cancer patients who have stopped responding to initial chemotherapy treatment. The trial will take place at the Oxford Radcliffe Hospitals NHS Trust.

29 Mar 2011

Protein C News and Research

Study finds frequent anaemia in patients with chronic respiratory failure

Two new studies on cancer

Basic Yellow 1 dye extends lifespan in healthy nematodes, slows Alzheimer's disease-like pathology in worms

Candy consumption can help reduce weight and risk of CVD

First transdisciplinary research center dedicated to identify causes of premature birth

Immunotec, NSU to conduct new research study in children with autism

Higher protein diets associated with greater feelings of fullness during weight loss

Essential protein linked to TNF induced inflammation

SLN to present Atu027 Phase I study data against solid cancer at ASCO Annual Meeting

Attacks by specific type of immune cells cause inflammations of heart muscle

Multiple drugs bonded to 'transport vehicle' bypass healthy cells to attack breast cancer from inside

Eya1 phosphatase controls fate of embryonic lung epithelial stem cells

Positive results from Vertex VX-770 Phase 3 trial against CF

Labcyte launches 1536-well tissue-culture treated microplate for cell-based screening

Oral antioxidant formulation before medical imaging may minimize cell damage

New lung cancer drug starts human trials

Protein aggregation plays a significant role in cancer

Scientists to discover new estrogen receptor-signaling networks for breast cancer treatment

Researchers find patients with Alzheimer's have lower glucose utilization in brain

International Phase II trial to study LY2181308 efficacy in patients with lung cancer

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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