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Cell-based test to discover molecules to treat ER-positive breast cancer

Cancer Research UK and its commercial arm, Cancer Research Technology have developed a unique test to discover molecules that could lead to potential new treatments for oestrogen receptor (ER)-positive breast cancer.

5 Mar 2012

Thrombotech receives FDA IND approval for THR-18 Phase IIa clinical trial in stroke victims

Hadasit Bio-Holdings a publicly traded portfolio of biotech companies, all based on intellectual property developed and owned by Hadassah University Hospital, Israel's foremost medical research center, today announced Thrombotech Ltd., a portfolio company which Hadasit holds a 24% stake in, received an IND approval from the Food and Drug Administration enabling the initiation of a Phase IIa clinical trial in the U.S.

5 Mar 2012

Anthera continues Phase 2b PEARL-SC clinical study in SLE patients

Anthera Pharmaceuticals, Inc., a biopharmaceutical company developing drugs to treat serious diseases including cardiovascular and autoimmune disorders, today announced the continuation of the Phase 2b PEARL-SC clinical study following an interim analysis of all safety and efficacy data.

5 Mar 2012

FDA confirms FluCide pre-IND meeting date with NanoViricides

NanoViricides, Inc. announced today that March 29th, 2012 has been confirmed by the US FDA as the date for its initial meeting with the Company's scientists. This pre-IND meeting will focus on FluCide, designated as NV-INF-1, the Company's novel anti-influenza drug.

5 Mar 2012

Researchers identify mechanism with which cancer cells protect themselves against damage

Although many cancer drugs have already been in use for decades, their mode of action is still unknown. The new research results now challenge a mechanism of action that was previously proposed for a group of drugs and supported with experiments: the Topoisomerase I-inhibitor Camptothecin (Top1 inhibitor for short) and its derivatives used in chemotherapy, Topotecan and Irinotecan.

5 Mar 2012

X-rays help decipher how natural antibiotics defy a longstanding set of chemical rules

Researchers working at the U.S. Department of Energy's (DOE) SLAC National Accelerator Laboratory have used powerful X-rays to help decipher how certain natural antibiotics defy a longstanding set of chemical rules - a mechanism that has baffled organic chemists for decades.

4 Mar 2012

Scientists discover how to enhance production of hepatocytes to repair damaged liver tissue

Scientists have shed light on how the liver repairs itself with research that could help develop drugs to treat liver disease.

4 Mar 2012

Contraception coverage flap becoming key issue in Senate races

Congress can't seem to stop its debate on birth control -- and one reason is that it's bringing in lots of votes and money. ... Republicans are also using the issue to raise money among conservatives and broaden GOP support among Catholics, who are strongly opposed to Obama's contraceptive mandate. But, in general, the flap over birth control is helping Democrats solidify their base and gives them an opening to appeal to independent women, said Jennifer Duffy of the Cook Political Report.

3 Mar 2012

SK Biopharmaceuticals' YKP3089 receives Korea Drug Development Fund

South Korean pharmaceutical company SK Biopharmaceuticals announced that the lead drug, YKP3089, from its drug development program for the treatment of refractory epilepsy, has been awarded funding from the Korea Drug Development Fund to support clinical development for the next three years.

3 Mar 2012

New pharma code expands guidelines for interactions with health care providers

A new practice code for pharmaceutical companies now covers all interactions with health care professionals and bans them from giving payments to doctors to attend conferences.

3 Mar 2012

Researchers identify mechanism by which cannabis affects working memory

A deterioration of working memory is observed in people who consume drugs containing cannabinoid compounds found in cannabis leaves and buds. A team led by Giovanni Marsicano in collaboration with a team led by Xia Zhang, has recently identified the mechanism by which these substances affect working memory.

3 Mar 2012

Roundup: Iowa lawmaker urges waiting on exchange bill until court rules; Calif. group finds way to recycle medicine

Democrats and Republicans disagree about whether the Legislature needs to approve a health insurance exchange this spring. At a Statehouse forum on the issue Thursday, state Sen. Brad Zaun noted that the U.S. Supreme Court is expected to rule this summer on whether major portions of the health reform law are constitutional. Zaun, an Urbandale Republican who opposes the overall law, said it makes sense to wait until after that decision before deciding whether to move ahead with the exchange.

3 Mar 2012

Viewpoints: The defeated Blunt Amendment, Obama's $100B Catholic hospital risk, fixing drug shortages

The amendment, which was attached to a highway bill, was defeated on a narrow 48-to-51 vote. But it showed once again how far from the mainstream Republicans have strayed in their relentless efforts to undermine the separation of church and state, deny women access to essential health services and tear apart President Obama's health care reform law.

3 Mar 2012

IFHP releases 2011 Comparative Price Report

The International Federation of Health Plans today released its 2011 Comparative Price Report detailing its annual survey of medical costs per unit. Designed to showcase the variation in healthcare costs around the world, the report examines the costs of medical procedures, tests, scans and treatments in nine countries.

3 Mar 2012

Early surgical intervention stops seizures and improves quality of life

While the thought of any type of surgery can be disconcerting, the thought of brain surgery can be downright frightening. But for people with a particular form of epilepsy, surgical intervention can literally be life-restoring.

3 Mar 2012

Abstinence therapy safer, preferable for opioid-addicted HCPs

Many health care professionals (HCPs) have easy access to controlled medications and the diversion and abuse of drugs among this group may be as high as 10%. Controversy surrounds the safety of allowing addicted HCPs to return to clinical practice while undergoing medical treatment with opioid substitution therapy such as buprenorphine.

3 Mar 2012

Critical new details about structure of enterovirus 71

Researchers have discovered critical new details about the structure of a virus that causes potentially fatal brain swelling and paralysis in children, pointing toward designs for antiviral drugs to treat the disease.

3 Mar 2012

CLR01 blocks toxic aggregations of proteins in mouse model of Parkinson's

Millions of people suffer from Parkinson's disease, a disorder of the nervous system that affects movement and worsens over time. As the world's population ages, it's estimated that the number of people with the disease will rise sharply. Yet despite several effective therapies that treat Parkinson's symptoms, nothing slows its progression.

2 Mar 2012

FDA takes more time to decide on the fate of BMS & Pfizer’s joint venture anticlotting drug Eliquis

The U.S FDA have pushed back the deadline for deciding whether to approve an experimental anticlotting drug developed jointly by Pfizer Inc. and Bristol-Myers Squibb Co. The companies said late Wednesday that the Food and Drug Administration has set a new target date of June 28 for deciding whether to approve Eliquis. That’s three months later than originally scheduled.

2 Mar 2012

HIV among injection drug users declines

U.S. health officials say the rate has dropped by half since the 1990s. The decline may be related to a growth in needle exchange programs. For the report more than 10,000 drug users in 20 metropolitan areas were surveyed and tested for HIV in 2009. About 1 in 10 tested positive for the virus. In the '90s, roughly 1 in 5 did. Addicts who inject heroin, cocaine or other drugs have been one of the groups hit hardest by AIDS.

2 Mar 2012