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Research shows potential way to limit damage to the brain caused by seizure disorder

Tiny vesicles isolated from adult mesenchymal stem cells and administered intranasally can limit the damage to the brain of animal models caused by a seizure disorder called status epilepticus, according to research published this week in the Proceedings of the National Academy of Sciences.

21 Apr 2017

Spermidine supplement may prolong lifespan, prevent liver fibrosis and cancer

Spermidine - a compound found in foods like aged cheese, mushrooms, soy products, legumes, corn and whole grains - seems to prevent (at least in animal models) liver fibrosis and hepatocellular carcinoma, which is the most common type of liver cancer. There is also some evidence that it may prolong lifespan, according to a study published recently in the journal Cancer Research.

20 Apr 2017

Fungi have immense potential for production of pharmaceutical compounds

Fungi are a potential goldmine for the production of pharmaceuticals. This is shown by researchers at Chalmers University of Technology, who have developed a method for finding new antibiotics from nature's own resources.

20 Apr 2017

Researchers discover molecular compound that targets nucleus of allergen-sensitized cells

Transcription factors, the tiny proteins that switch genes on or off in the nucleus of cells, are considered unreachable molecular targets for drugs attempting to treat medical conditions.

18 Apr 2017

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Cocaine, nicotine, capsaicin. These are just three familiar examples of the hundreds of thousands of small molecules (also called specialized or secondary metabolites) that plants use as chemical ammunition to protect themselves from predation.

17 Apr 2017

Researchers uncover global regulator that 'switches on' silent biosynthetic gene clusters

Bacteria have supplied some of today's most indispensable anti-cancer and anti-bacterial drugs. Yet these compounds comprise only a fraction of their possible offerings. Now, researchers have found a way to unleash their full potential as natural product dispensers.

13 Apr 2017

Clemson University researcher receives NIH grant to advance study into abdominal aortic aneurysms

One of the top ten killers for men older than 55 is the target of Clemson University research that could lead to a new life-saving therapy and a better way of telling whether surgery is necessary.

12 Apr 2017

Study finds increasing trends in use of CVI treatment procedures in Medicare population

A new study by the Harvey L. Neiman Health Policy Institute found that utilization of procedures to treat chronic venous insufficiency (CVI) in the Medicare population increased markedly from 2005 through 2014.

12 Apr 2017

KU researcher reveals possible therapeutic intervention for 'chemobrain' in cancer patients

Findings offered by a University of Kansas researcher, identified as one of 20 'Must See Presenters' at the national meeting of the American Chemical Society in early April, suggest a possible therapeutic intervention for "chemobrain," the cognitive impairment plaguing up to a third of cancer patients following chemotherapy.

12 Apr 2017

Scientists discover how insulin-producing cells show differences in age

Diabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets.

12 Apr 2017

Microparticles show potential to deliver DNA-based vaccines and gene therapies in pill form

A microscopic corn-and-shrimp cocktail could eventually make DNA-based vaccinations and cancer-treating gene therapies an easier pill to swallow, according to new research from the University of Nebraska-Lincoln.

12 Apr 2017

Researchers design first light-activated drug for treatment of pain

A team of the Institute of Neurosciences of the University of Barcelona has participated in the design of the first light-activated drug -the JF-NP-26, for the treatment of pain, according to a research with animal models published in the journal eLife.

11 Apr 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

Genomic Analysis Technologies: Past, Present and Future

In this interview, Jay Flatley, Executive Chairman of Illumina, gives an introduction to Illumina and the next generation genomics tools they provide.

From Pittcon 10 Apr 2017

Rutgers scientists reveal structure of TB drug target and identify new inhibitors

Rutgers University scientists have determined the three-dimensional structure of the target of the first-line anti-tuberculosis drug rifampin. They have also discovered a new class of potential anti-tuberculosis drugs that kill rifampin-resistant and multi-drug-resistant tuberculosis bacteria.

7 Apr 2017

Honey bees have better vision than previously known

Research conducted at the University of Adelaide has discovered that bees have much better vision than was previously known, offering new insights into the lives of honey bees, and new opportunities for translating this knowledge into fields such as robot vision.

6 Apr 2017

X-ray study sheds new light on promising drug target

Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins adorning cell surfaces, which are the targets of the majority of pharmaceutical drugs.

5 Apr 2017

Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

5 Apr 2017

Researchers develop stable brain implant based on anti-inflammatory coating

Complex neurotechnological devices are required to directly select and influence brain waves inside the skull's interior. Although it has become relatively easy to implement the devices, researchers are still faced with challenges when trying to keep them running properly in living organisms over time.

5 Apr 2017

Newly-discovered mechanism for compound may help prevent neurologic damage

Researchers at Oregon State University have found that a compound called rapamycin has unusual properties that may help address neurologic damage such as Alzheimer's disease.

5 Apr 2017

Compound News and Research

Research shows potential way to limit damage to the brain caused by seizure disorder

Spermidine supplement may prolong lifespan, prevent liver fibrosis and cancer

Fungi have immense potential for production of pharmaceutical compounds

Researchers discover molecular compound that targets nucleus of allergen-sensitized cells

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Researchers uncover global regulator that 'switches on' silent biosynthetic gene clusters

Clemson University researcher receives NIH grant to advance study into abdominal aortic aneurysms

Study finds increasing trends in use of CVI treatment procedures in Medicare population

KU researcher reveals possible therapeutic intervention for 'chemobrain' in cancer patients

Scientists discover how insulin-producing cells show differences in age

Microparticles show potential to deliver DNA-based vaccines and gene therapies in pill form

Researchers design first light-activated drug for treatment of pain

New study finds link between neural tube defects in infants and neurodegenerative diseases

Genomic Analysis Technologies: Past, Present and Future

Rutgers scientists reveal structure of TB drug target and identify new inhibitors

Honey bees have better vision than previously known

X-ray study sheds new light on promising drug target

Cellular markers of aging could reveal how insulin-producing cells begin to fail in type 2 diabetes

Researchers develop stable brain implant based on anti-inflammatory coating

Newly-discovered mechanism for compound may help prevent neurologic damage

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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