Infectious Diseases News and Research

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Purdue researchers use malaria expertise to track COVID-19 in Indiana

Scientists have been using genetics to track diseases for decades. Now, a team at Purdue University that typically tracks malaria spread in Southern and Central Africa is using its expertise to track COVID-19 in Indiana.

8 Apr 2021

Phase 2 clinical trial launched in Thailand to evaluate IL-15 agonist as therapy to reduce HIV reservoir

The U.S. Military HIV Research Program (MHRP) at the Walter Reed Army Institute of Research last week launched a Phase 2 clinical trial in Thailand to evaluate an interleukin-15 (IL-15) superagonist, ImmunityBio's Anktiva (also called N-803), administered during acute HIV infection as an experimental therapy to target establishment of the HIV reservoir at a very early stage.

8 Apr 2021

Moderna COVID-19 vaccine ensures long-term protection against SARS-CoV-2 infection, suggests study

A recent report published in the New England Journal of Medicine has revealed that the COVID-19 vaccine developed by Moderna, Inc, USA, is capable of inducing robust and durable antibody responses for at least six months post-vaccination.

8 Apr 2021

Inhibition of NLRP3 complex can reduce inflammation in melanoma patients

Cancer doctors may soon have a new tool for treating melanoma and other types of cancer, thanks to work being done by researchers at the University of Colorado Cancer Center.

8 Apr 2021

Cross-border asthma study investigates hygiene hypothesis amid COVID-19 pandemic

A cross-border investigation of children's susceptibility to asthma and other childhood illnesses in the United States and Mexico is the focus of a new study led by researchers in the Asthma and Airway Disease Research Center at the University of Arizona Health Sciences.

8 Apr 2021

Bispecific antibodies neutralize SARS-CoV-2 and its variants

A new bioRxiv preprint study led by Joshua Tan from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, involves generating bispecific antibodies using a new method cross-linking the antibodies with adjacent spike proteins using dual N-terminal domain/receptor binding domain specificity.

7 Apr 2021

Michigan Medicine to kick off first national study on allergic reactions to COVID-19 vaccines

In a carefully controlled study, Michigan Medicine researchers will kick off the first national trial to study allergic reactions to the COVID-19 mRNA vaccines.

7 Apr 2021

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

A clinical trial is underway to determine whether people who are highly allergic or have a mast cell disorder are at increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines.

7 Apr 2021

World Health Day 2021: The humanitarians building a fairer world

In commemoration of World Health Day 2021, News-Medical interviews the International Medical Corps on how they are helping to achieve a fairer and healthier world.

7 Apr 2021

CoVIg-19 Plasma Alliance announces outcomes of NIH-funded Phase 3 ITAC clinical trial

The CoVIg-19 Plasma Alliance today announced that the Phase 3 Inpatient Treatment with Anti-Coronavirus Immunoglobulin (ITAC) clinical trial sponsored and funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), did not meet its endpoints. No serious safety signals were raised in the trial.

7 Apr 2021

Study suggests T-cells don't determine survival in severe COVID-19

In the study, which appeared on the pre-print server medRxiv, the team found that when the monkeys were reinfected, the T cell-depleted animals showed anamnestic immune responses, the enhanced reaction of the body's immune system to an antigen that is related to an antigen previously encountered.

6 Apr 2021

Vermont to give minority residents vaccine priority

States have tried with limited success to get covid vaccines to people of color, who have been disproportionately killed and hospitalized by the virus.

5 Apr 2021

Phase 1 clinical study of unique vaccine to protect against COVID-19 begins

A unique vaccine to protect against COVID-19 begins clinical testing Tuesday, 6 April, at the Walter Reed Army Institute of Research (WRAIR), part of the U.S. Army Medical Research and Development Command.

5 Apr 2021

FIND announces launch of a request for proposals to expand access to COVID-19 testing services

The Foundation for Innovative New Diagnostics (FIND) announced today the launch of a request for proposals (RFP) to accelerate the development, manufacturing, and market availability of accurate, affordable, quality-assured and easy-to-use SARS-CoV-2 self-tests for use in low- and middle-income countries (LMICs).

5 Apr 2021

Chemical inhibitor can reduce SARS-CoV-2's ability to infect host cell lines

James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has long studied neglected tropical diseases -- chronic and disabling parasitic infections that primarily affect poor and underserved communities in developing nations.

3 Apr 2021

Research offers new clues about the underlying mechanisms of itch

Eczema, or atopic dermatitis (AD), is sometimes called "the itch that rashes." Often, the itch begins before the rash appears, and, in many cases, the itchiness of the skin condition never really goes away.

3 Apr 2021

Study finds CD8+ T cell responses detect all major SARS-CoV-2 variants

There have been concerns that several SARS-CoV-2 variants have mutations that allow them to evade the immune system. A new study published in the Open Forum Infectious Diseases suggests otherwise. Led by Aaron AR Tobian of Johns Hopkins University School of Medicine, results showed that except for one from the B.1.351 variant, CD8+ T cells showed a broad response to all SARS-CoV-2 variants.

2 Apr 2021

Beating the pavement to vaccinate the underrepresented — and protect everyone

Leonor Garcia held her clipboard close to her chest and rapped on the car window with her knuckles. The driver was in one of dozens of cars lined up on a quiet stretch of road in Adelanto, California, a small city near the southwestern edge of the Mojave Desert.

2 Apr 2021

Study investigates the efficacy of COVID-19 vaccines over longer term

COVID-19 vaccines were designed to reduce the likelihood that infection by the SARS-CoV-2 virus would lead to severe outcomes, such as hospitalization and death. In that sense, all of the currently approved vaccines -- Moderna, Pfizer and Johnson & Johnson -- have proven comparably effective.

2 Apr 2021

Highly contagious SARS-CoV-2 variant was spreading for months before its discovery

A highly contagious SARS-CoV-2 variant was unknowingly spreading for months in the United States by October 2020, according to a new study from researchers with The University of Texas at Austin COVID-19 Modeling Consortium.

2 Apr 2021

Infectious Diseases News and Research

Purdue researchers use malaria expertise to track COVID-19 in Indiana

Phase 2 clinical trial launched in Thailand to evaluate IL-15 agonist as therapy to reduce HIV reservoir

Moderna COVID-19 vaccine ensures long-term protection against SARS-CoV-2 infection, suggests study

Inhibition of NLRP3 complex can reduce inflammation in melanoma patients

Cross-border asthma study investigates hygiene hypothesis amid COVID-19 pandemic

Bispecific antibodies neutralize SARS-CoV-2 and its variants

Michigan Medicine to kick off first national study on allergic reactions to COVID-19 vaccines

NIH-funded clinical trial begins study of systemic allergic reactions to COVID-19 vaccines

World Health Day 2021: The humanitarians building a fairer world

CoVIg-19 Plasma Alliance announces outcomes of NIH-funded Phase 3 ITAC clinical trial

Study suggests T-cells don't determine survival in severe COVID-19

Vermont to give minority residents vaccine priority

Phase 1 clinical study of unique vaccine to protect against COVID-19 begins

FIND announces launch of a request for proposals to expand access to COVID-19 testing services

Chemical inhibitor can reduce SARS-CoV-2's ability to infect host cell lines

Research offers new clues about the underlying mechanisms of itch

Study finds CD8+ T cell responses detect all major SARS-CoV-2 variants

Beating the pavement to vaccinate the underrepresented — and protect everyone

Study investigates the efficacy of COVID-19 vaccines over longer term

Highly contagious SARS-CoV-2 variant was spreading for months before its discovery

Industry Focus eBook - Infectious Diseases (3rd Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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