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New trial assesses criteria used to diagnose myocardial infarction

Results of the first randomized trial testing the criteria used to diagnose heart attack are presented today in a Hot Line Session at ESC Congress 2018 and published in The Lancet.

28 Aug 2018

New Cochrane Review assesses accuracy of Xpert in diagnosing extrapulmonary TB

In one-fifth of people with active tuberculosis, the site of disease is outside the lungs. Some forms of extrapulmonary TB, such as TB meningitis, are extremely dangerous, where a rapid diagnosis can make all the difference to a patient.

28 Aug 2018

Scientists develop urine diagnostic to detect parasitic worms that cause river blindness

Scientists at Scripps Research have developed a urine diagnostic to detect the parasitic worms that cause river blindness, also called onchocerciasis, a tropical disease that afflicts 18 to 120 million people worldwide.

28 Aug 2018

Advanced microscopes determine structure of molecular complex implicated in several cancers

In a study published today in Science, UT Southwestern and Rockefeller University researchers used advanced microscopes to determine at atomic resolution the structure of a molecular complex implicated in birth defects and several cancers.

24 Aug 2018

Scientists identify novel biomarkers that indicate risk of polyneuropathy

Polyneuropathy is one of the most common complications in people with diabetes. However, it can also occur with certain risk factors or diseases before the onset of diabetes.

23 Aug 2018

Study: Motor cortex necessary for movement control in response to unexpected situations

Scientists have demonstrated that the motor cortex is necessary for the execution of corrective movements in response to unexpected changes of sensory input but not when the same movements are executed spontaneously.

23 Aug 2018

New reagents added to the CLC800 and CLC1500 clinical analyzers

Carolina Liquid Chemistries Corp. have recently added three moderately complex reagents to the CLC800 and the CLC1600 clinical chemistry analyzers.

From Carolina Liquid Chemistries Corp. 23 Aug 2018

Simple paper-based test identifies falsified and substandard antibiotics

Antibiotics - medicines that treat bacterial infections - have saved millions of lives worldwide since their discovery in the early 20th century.

22 Aug 2018

FDA approves Dako PD-L1 IHC 22C3 pharmDx assay for expanded use in urothelial carcinoma

Agilent Technologies Inc. today announced that the U.S. Food and Drug Administration has approved its Dako PD-L1 IHC 22C3 pharmDx assay for expanded use in urothelial carcinoma.

22 Aug 2018

Aravive Biologics gains Fast Track Designation for AVB-S6-500 from U.S. FDA

Aravive Biologics, Inc. announced today that the U.S. Food and Drug Administration has granted Fast Track Designation to AVB-S6-500 as a potential treatment for platinum-resistant recurrent ovarian cancer.

20 Aug 2018

New assay may help improve both sarcoma diagnosis and treatment

Sarcomas are rare tumors that are often misdiagnosed. Specific recurrent chromosomal rearrangements, known as translocations, can serve as essential diagnostic markers and are found in about 20 percent of sarcomas.

20 Aug 2018

Novel finger-prick test can help prevent toxoplasmosis

A recent study, performed in Chicago and Rabat, Morocco, found that a novel finger-prick test for infection with the parasite Toxoplasma gondii during pregnancy - and many other potential applications - is 100 percent sensitive and 100 percent specific for detecting the presence of this life-damaging microorganism.

17 Aug 2018

Discovery may help broaden the scope of defenses against HPV

Yale Cancer Center scientists have filled in a key gap in understanding the unusual route by which the Human papillomavirus infects cells.

16 Aug 2018

FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Vertex Pharmaceuticals Incorporated today announced the U.S. Food and Drug Administration approved KALYDECO® (ivacaftor) to include use in children with cystic fibrosis ages 12 to <24 months who have at least one mutation in their cystic fibrosis transmembrane conductance regulator gene that is responsive to KALYDECO based on clinical and/or in vitro assay data.

16 Aug 2018

Study provides new insight into how 'trash bag of the cell' traps and seals off waste

The mechanics behind how an important process within the cell traps material before recycling it has puzzled scientists for years. But Penn State researchers have gained new insight into how this process seals off waste, much like a trash bag.

16 Aug 2018

FIND and genedrive announce study agreement to evaluate HCV ID Kit

genedrive plc, a near patient molecular diagnostics company, and the Foundation for Innovation of New Diagnostics (FIND), announced today a study agreement for the performance evaluation of genedrive plc’s hepatitis C virus (HCV) Genedrive HCV ID Kit.

10 Aug 2018

GNA Biosolutions named as winner of AACC Disruptive Technology Award

GNA Biosolutions was named the winner of the American Association of Clinical Chemistry’s (AACC) Disruptive Technology Award competition, held on Monday evening at the 70th AACC Annual Scientific Meeting & Clinical Lab Expo in Chicago, Illinois. The AACC Disruptive Technology Award recognizes innovative testing solutions that improve patient care through diagnostic performance or access to high-quality testing. GNA Biosolutions also won the audience choice award.

From HP Health Solutions Germany GmbH 10 Aug 2018

Study finds false negatives in common tests used to determine ROS1 status in lung cancer

Drugs like crizotinib are used to treat patients with ROS1-positive lung cancer. But which patients are ROS1-positive? A University of Colorado Cancer Center study published in the Journal of Thoracic Oncology shows that common laboratory tests used to determine ROS1 status all have inherent limitations that can lead to false-negative results.

9 Aug 2018

Cancer cells release biological 'drones' to assist in the fight against immune system

Cancer cells are more than a lump of cells growing out of control; they participate in active combat with the immune system for their own survival. Being able to evade the immune system is a hallmark of cancer.

9 Aug 2018

Blood-based test accurately identifies lung cancer patients who could benefit from immunotherapies

Researchers at UC Davis, Genentech and Foundation Medicine are the first to show that a blood-based test to assess tumor mutational burden accurately identifies non-small cell lung cancer (NSCLC) patients who could benefit from immunotherapies called checkpoint inhibitors.

7 Aug 2018

Assay News and Research

New trial assesses criteria used to diagnose myocardial infarction

New Cochrane Review assesses accuracy of Xpert in diagnosing extrapulmonary TB

Scientists develop urine diagnostic to detect parasitic worms that cause river blindness

Advanced microscopes determine structure of molecular complex implicated in several cancers

Scientists identify novel biomarkers that indicate risk of polyneuropathy

Study: Motor cortex necessary for movement control in response to unexpected situations

New reagents added to the CLC800 and CLC1500 clinical analyzers

Simple paper-based test identifies falsified and substandard antibiotics

FDA approves Dako PD-L1 IHC 22C3 pharmDx assay for expanded use in urothelial carcinoma

Aravive Biologics gains Fast Track Designation for AVB-S6-500 from U.S. FDA

New assay may help improve both sarcoma diagnosis and treatment

Novel finger-prick test can help prevent toxoplasmosis

Discovery may help broaden the scope of defenses against HPV

FDA expands approval of Vertex' cystic fibrosis medicine to treat children aged 12 to <24 months

Study provides new insight into how 'trash bag of the cell' traps and seals off waste

FIND and genedrive announce study agreement to evaluate HCV ID Kit

GNA Biosolutions named as winner of AACC Disruptive Technology Award

Study finds false negatives in common tests used to determine ROS1 status in lung cancer

Cancer cells release biological 'drones' to assist in the fight against immune system

Blood-based test accurately identifies lung cancer patients who could benefit from immunotherapies

Microplate-based assays in microbiology research eBook eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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