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Long-read sequencing uncovers massive DNA elements shaping human oral microbiome

Researchers including those at the University of Tokyo have made a surprising discovery hiding in people's mouths: Inocles, giant DNA elements that had previously escaped detection.

10 Sep 2025

Microbial piracy offers clues to fighting antimicrobial resistance

Researchers have discovered how 'pirate phages' hijack other viruses to break into bacteria, sharing new genetic material for dangerous traits.

10 Sep 2025

Specific microbial changes linked to poor growth in children

Malnutrition is responsible for more than half of all deaths in children under the age of five worldwide.

10 Sep 2025

New AI model can identify treatments that reverse disease states in cells

In a move that could reshape drug discovery, researchers at Harvard Medical School have designed an artificial intelligence model capable of identifying treatments that reverse disease states in cells.

10 Sep 2025

New technique used to conduct real-time measurement of boron in live tumor cells

A new technique has measured boron in individual cancer cells for the first time, enabling researchers to better understand how drugs act to kill tumors in some cancers.

10 Sep 2025

Rapid neuronal evolution linked to high prevalence of autism in humans

A new paper in Molecular Biology and Evolution, published by Oxford University Press, finds that the relatively high rate of Autism-spectrum disorders in humans is likely due to how humans evolved in the past.

10 Sep 2025

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Using tiny particles shaped like bottlebrushes, MIT chemists have found a way to deliver a large range of chemotherapy drugs directly to tumor cells.

10 Sep 2025

Subcutaneous amivantamab plus lazertinib yields high response in EGFR-mutant lung cancer

A new analysis from the PALOMA-2 study presented today shows that subcutaneous administration of amivantamab every four weeks (Q4W), in combination with daily oral lazertinib, yields a high objective response rate in patients with previously untreated EGFR-mutated advanced non-small cell lung cancer (NSCLC).

10 Sep 2025

Johns Hopkins team develops urine-based test for prostate cancer detection

Researchers at the Johns Hopkins Kimmel Cancer Center, Johns Hopkins All Children's Hospital and four other institutions have devised a novel method to test for prostate cancer using biomarkers present in urine, funded in part by the National Institutes of Health.

9 Sep 2025

Kids with fluctuating gut microbiome show poorer growth

Malnutrition is a leading cause of death in children under age 5, and nearly 150 million children globally under this age have stunted growth from lack of nutrition.

9 Sep 2025

Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

A special MRI technique that detects iron levels in different regions of the brain can predict the onset of mild cognitive impairment and cognitive decline in cognitively unimpaired older adults, potentially creating a pathway to earlier interventions, according to a study published today in Radiology, a journal of the Radiological Society of North America.

9 Sep 2025

Study maps gene activity across pregnancy breastfeeding and post-weaning stages

In a study in mice, researchers have identified genes associated with the dramatic transformation of the mammary gland in pregnancy, breastfeeding, and after breastfeeding as it returns to its resting state.

9 Sep 2025

Researchers reveal why no level of air pollution is safe for respiratory health

A review in the Journal of Clinical Investigation shows how particulate matter damages the lungs through oxidative stress, inflammation, and immune disruption. It links air pollution to asthma, COPD, lung cancer, infections, and millions of premature deaths, with no safe exposure threshold.

9 Sep 2025

IFITM3 found to be critical regulator of immunotherapy sensitivity in small cell lung cancer

New research presented identifies interferon-induced transmembrane protein 3 (IFITM3) as a critical regulator of immunotherapy sensitivity in small cell lung cancer (SCLC), offering a promising new avenue for overcoming resistance to PD-1/PD-L1 checkpoint blockade.

9 Sep 2025

Amino acid homocysteine plays a key role in aortic stiffening

In addition to cholesterol, the amino acid homocysteine also plays a role in aortic stiffening. Researchers from Graz University of Technology, the University of Graz and the Medical University of Graz were able to prove this in a new study.

9 Sep 2025

Researchers uncover a previously unknown mechanism behind chromosome end protection

Researchers have uncovered a previously unknown mechanism that safeguards the chromosome ends from being mistakenly repaired by the cell.

9 Sep 2025

New tool can predict where deadly brain cancer might reappear

Glioblastoma is a devastatingly effective brain cancer. Doctors can cut it out or blast it with radiation, but that only buys time. The cancer has an insidious ability to hide enough tumor cells in tissue around the tumor to allow it to return as deadly as ever.

9 Sep 2025

Monitoring ctDNA can personalize the use of consolidation immunotherapy in patients with LS-SCLC

A new study presented at the International Association for the Study of Lung Cancer 2025 World Conference on Lung Cancer (WCLC) demonstrates that monitoring circulating tumor DNA (ctDNA) can refine and personalize the use of consolidation immunotherapy in patients with limited-stage small cell lung cancer (LS-SCLC).

9 Sep 2025

New feedback mechanism in the brain could open avenues for treating people with sleep disorders

As every bodybuilder knows, a deep, restful sleep boosts levels of growth hormone to build strong muscle and bone and burn fat.

9 Sep 2025

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

Nina Kumowski, MD, of the Department of Radiology and Center for Systems Biology at Massachusetts General Hospital, is the lead author and Matthias Nahrendorf, MD, PhD of the Department of Radiology and Center for Systems Biology at MGH, is the senior author of a paper published in Science, "Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia."

9 Sep 2025

Cell News and Research

Long-read sequencing uncovers massive DNA elements shaping human oral microbiome

Microbial piracy offers clues to fighting antimicrobial resistance

Specific microbial changes linked to poor growth in children

New AI model can identify treatments that reverse disease states in cells

New technique used to conduct real-time measurement of boron in live tumor cells

Rapid neuronal evolution linked to high prevalence of autism in humans

Bottlebrush particles deliver large range of chemotherapy drugs directly to tumor cells

Subcutaneous amivantamab plus lazertinib yields high response in EGFR-mutant lung cancer

Johns Hopkins team develops urine-based test for prostate cancer detection

Kids with fluctuating gut microbiome show poorer growth

Special MRI technique predicts onset of mild cognitive impairment and cognitive decline

Study maps gene activity across pregnancy breastfeeding and post-weaning stages

Researchers reveal why no level of air pollution is safe for respiratory health

IFITM3 found to be critical regulator of immunotherapy sensitivity in small cell lung cancer

Amino acid homocysteine plays a key role in aortic stiffening

Researchers uncover a previously unknown mechanism behind chromosome end protection

New tool can predict where deadly brain cancer might reappear

Monitoring ctDNA can personalize the use of consolidation immunotherapy in patients with LS-SCLC

New feedback mechanism in the brain could open avenues for treating people with sleep disorders

'Resistin like molecule gamma' punches holes into heart cells after myocardial infarction

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