Hormones News and Research

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CYP1B1 protein may be a potential target for intervention in head and neck cancer

Squamous cell carcinoma of the head and neck-which typically arises from thin, flat cells that line moist surfaces inside the mouth, nose and throat-is the sixth most common type of cancer worldwide, and it has a relatively low five-year survival rate and a high recurrence rate.

2 Apr 2012

TGen to present TNBC study at AACR 2012 annual meeting

Because cases of Triple-Negative Breast Cancer (TNBC) are so genetically different, whole-genome sequencing is needed to detect the subtle molecular differences that might point to specific treatments for individual patients.

2 Apr 2012

Hormones use and breast cancer risk

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1 Apr 2012

Number of kidney cancer cases rises over 9,000 in Great Britain

The number of cases of kidney cancer diagnosed each year in Great Britain has risen over 9,000 for the first time, new figures from Cancer Research UK show today.

31 Mar 2012

Blood levels of PCBs in polar bear cubs appear to have dropped

It's never been easy to be a polar bear. They may have to go months without eating. Their preferred food, seal, requires enormous luck and patience to catch. Add to that the melting of Arctic sea ice due to climate change, and the poisoning of the Arctic by toxic chemicals, and it's easy to see why polar bears worldwide are in trouble.

30 Mar 2012

BPA shows tangible effects on health endpoints at high dosage levels

Endocrine-disrupting chemicals (EDCs)-such as BPA-can show tangible effects on health endpoints at high dosage levels, yet those effects do not predict how EDCs will affect the endocrine system at low doses, according to a recent study accepted for publication in The Endocrine Society's Endocrine Reviews.

30 Mar 2012

Cancer death rates declining but obesity still needs to be tackled

According to a new report from four major national cancer tracking groups there has been a steady decline in cancer death rates for men, women and children from 2004 to 2008. The declines in death and new cases of cancer reflect progress against the disease in terms of prevention, diagnosis and treatment, but experts say rising obesity may present a new challenge in the fight against cancer.

29 Mar 2012

Stress response reduces memory during tests in older adults

Your mother had a doctor's appointment for a memory test. The results are conclusive: she presents with the first signs of Alzheimer type dementia. Now, to get to her appointment, your mother, who is no longer used to driving in town, took her car, looked for a parking space for 15 minutes, got lost in a labyrinth of one-way streets, had never used those new electronic parking meters before and is convinced that the "machine" stole her credit card number.

28 Mar 2012

Intermittent androgen suppression therapy for prostate cancer

Androgen suppression - the inhibition of testosterone and other male hormones - is a routine therapy for prostate cancer. Unfortunately, it can dramatically reduce the quality of patients' sex lives and, more importantly, lead to cancer recurrence in a more deadly androgen-independent form.

28 Mar 2012

First study to explore differential gender effects of secondhand smoke exposure

The negative health effects of early-life exposure to secondhand smoke appear to impact girls more than boys-particularly those with early-life allergic sensitization, according to new research from the University of Cincinnati (UC) College of Medicine.

27 Mar 2012

Scientist develops a way to encase nutraceuticals in food-based products

A Purdue University food scientist has developed a way to encase nutritional supplements in food-based products so that one day consumers might be able to sprinkle vitamins, antioxidants and other beneficial compounds right onto their meals.

27 Mar 2012

Ripeness of fruit determines how food-poisoning bacteria grow on them

The ripeness of fruit could determine how food-poisoning bacteria grow on them, according to scientists presenting their work at the Society for General Microbiology's Spring Conference in Dublin this week. Their work could lead to new strategies to improve food safety, bringing many health and economic benefits.

27 Mar 2012

Transplanted ovaries can delay menopause and allow for a successful pregnancy

Researchers may have found a way to end menopause after proving that transplanted ovaries remain effective for at least seven years. Of the three women, one has had three children since her transplant, a second has had two and the third is expecting her third child. Medical experts believe the three could be the pioneers for a treatment that would allow women to delay motherhood.

26 Mar 2012

Pregnancy raises risk of heart attacks

According to a new study pregnancy and related hormonal changes that continue 12 weeks after giving birth increase a woman's risk of heart attack. Although the likelihood of having a heart attack during pregnancy is very low - just 1 in every 16,000 deliveries - it is still 3 to 4 times higher than non-pregnant women of the same age.

26 Mar 2012

Obese or overweight women may have increased risk of breast cancer recurrence

Women who are overweight or obese when they are diagnosed with breast cancer are at higher risk of cancer recurrence or related death than are leaner women, according to a new study to be presented to the 8th European Breast Cancer Conference.

26 Mar 2012

Higher risk of breast cancer recurrence in overweight, obese women

23 Mar 2012

No added benefit of aliskiren-amlodipine fixed drug combination for hypertension

The fixed drug combination of aliskiren and amlodipine (trade name: Rasilamlo-) was approved in April 2011 for the treatment of people with hypertension in whom aliskiren or amlodipine alone has an insufficient effect.

23 Mar 2012

UC Riverside to study molecular basis of hormonal regulation of mosquito reproduction

Female mosquitoes require energy for their egg development, which they acquire from vertebrate blood. But by sucking on blood, they become vectors of numerous disease pathogens of human and domestic animals. If the mechanisms that govern their egg production are better understood, novel approaches to controlling the reproduction and population of mosquitoes can be devised.

23 Mar 2012

Study finds higher death rate in calorie-restricted models of IBD

In a surprising result, Michigan State University researchers looking at the effects of diet on bowel disease found that mice on a calorie-restricted diet were more likely to die after being infected with an inflammation-causing bacterial pathogen in the colon.

21 Mar 2012

Obesity gene mutation identified in mice

A new study has found why a mutation in a particular gene can lead to obesity. Mouse experiments suggested the body's message to “stop eating” was blocked if the animals had the mutation. The study, published in Nature Medicine, said the brain's response to appetite hormones was being disrupted.

20 Mar 2012