Malignant News and Research

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LC-MRM could provide better understanding of multiple myeloma drug resistance

12 Sep 2011

Human gliomas release excess levels of glutamate and trigger seizures

Glioma, one of the most deadly and common types of brain tumor, is often associated with seizures, but the origins of these seizures and effective treatments for them have been elusive. Now a team funded by the National Institutes of Health has found that human gliomas implanted in mice release excess levels of the brain chemical glutamate, overstimulating neurons near the tumor and triggering seizures.

12 Sep 2011

Study pinpoints relationship between primary brain tumors and onset of epileptic seizures

New research from the University of Alabama at Birmingham pinpoints the relationship between primary brain tumors and the onset of epileptic seizures and reveals that a drug used to treat Crohn's disease inhibits those seizures and may be able to slow a tumor's growth.

12 Sep 2011

Moffitt researchers employ LC-MRM to detect acquired multiple myeloma drug resistance

"Acquired drug resistance" (ADR) is a major problem encountered in treating some forms of cancer. The ability to monitor the proteins involved in drug resistance has been a hurdle facing cancer researchers. However, a team of researchers at Moffitt Cancer Center, and colleagues, are pioneering promising research utilizing a monitoring technology that could provide a better understanding of ADR and assist in clinical decision-making for developing individualized patient treatments for multiple myeloma.

9 Sep 2011

Aura's NanoSmart platform can enable earlier detection, treatment of cancers

Aura Biosciences, Inc., a biotech company focused on the development of nano-enabled drug delivery systems, has completed several pre-clinical research programs. The resulting data suggest that Aura's NanoSmart platform can enable earlier detection of cancers and distant metastases; and then provide precisely targeted treatment of those cancers.

9 Sep 2011

Ohio Third Frontier grants to advance Philips Healthcare Global Advanced Imaging Innovation Center

The Ohio Third Frontier Commission has awarded $2.5 million in research grants to advance the Philips Healthcare Global Advanced Imaging Innovation Center, a collaboration among Case Western Reserve University, University Hospitals (UH) Case Medical Center and Philips Healthcare. The research projects are part of $30 million in funding awarded throughout the State of Ohio this week by the Ohio Third Frontier Commission.

8 Sep 2011

New study to better understand relapsed medulloblastoma in children

Children with medulloblastoma, (a type of malignant brain tumour), undergo extensive and debilitating treatment, which has led to marked improvements in survival rates over recent decades. Despite this, these tumours will return in a proportion of patients following treatment (termed relapse), and the vast majority of these will succumb to their disease.

8 Sep 2011

Combination of blood tests and ROMA algorithm receives FDA clearance to treat ovarian cancer

Approval last week by U.S. Food and Drug Administration (FDA) clears the path for nationwide use of tools that show the greatest specificity in estimating the risk of ovarian cancer in women with a pelvic mass.

7 Sep 2011

SYSU, ASU collaborate to develop early and predictive diagnostics for colorectal cancer

Arizona State University (ASU) and China's Sun Yat-Sen University (SYSU) have formalized a research collaboration aimed at developing early and predictive diagnostics to improve patient outcomes for colorectal cancer.

7 Sep 2011

Researchers use ultrasound to improve quality of blood stem cell transplant

Transplantation of haematopoietic stem cells is an effective treatment for patients with malignant blood diseases. The composition and quality of the transplanted cells are crucial to the outcome. Researchers from Lund University, Sweden, have now developed a method to improve the quality of the transplanted cells using ultrasound for cell separation.

7 Sep 2011

Fujirebio Diagnostics receives FDA 510(k) clearance for Risk of Ovarian Malignancy Algorithm test

Fujirebio Diagnostics, the industry leader in oncology biomarker assays, announced today that it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) to market the company's HE4 Test in an algorithm called ROMA (HE4 EIA + ARCHITECT CA 125 II) to aid in assessing whether a premenopausal or postmenopausal woman who presents with an ovarian adnexal mass is at high or low likelihood of finding malignancy on surgery.

7 Sep 2011

Biologists identify mechanism of H. pylori that damages DNA of gastric mucosal cells

The stomach bacterium Helicobacter pylori is one of the biggest risk factors for the development of gastric cancer, the third most common cause of cancer-related deaths in the world.

6 Sep 2011

Study sheds new light on the state of Europe's mental and neurological health

A major landmark study released today by the European College of Neuropsychopharmacology (ECNP) sheds new light on the state of Europe's mental and neurological health.

5 Sep 2011

Asbestos related cancer risk rises after home renovations: Study

A third wave of asbestos-related cancers is emerging as the rate of malignant mesothelioma caused by exposure to asbestos during home renovations increases dramatically, according to new research.

5 Sep 2011

Researchers discover new genetic defect that predisposes people to leukemia, myelodysplasia

A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts as a master control during the transition of primitive blood-forming cells into white blood cells.

5 Sep 2011

Neutrophils linked to growth and spread of cancer

Scripps Research Professor James Quigley, Staff Scientist Elena Deryugina, and colleagues had previously demonstrated that white blood cells known as neutrophils—bone marrow-derived cells that function as "first responders" at sites of acute inflammation—promote the growth of new blood vessels in normal, healthy tissue.

2 Sep 2011

Valproic acid may increase survival for brain tumor patients

New research suggests brain tumor patients who take the seizure drug valproic acid on top of standard treatment may live longer than people who take other kinds of epilepsy medications to control seizures.

2 Sep 2011

CRI announces winners of 2011 Coley Award for distinguished research in tumor immunology

The Cancer Research Institute, Inc. (CRI), a U.S. nonprofit organization established in 1953 to advance the science of tumor immunology and drive the discovery of new cancer immunotherapies, announced today the winners of the 2011 William B. Coley Award for Distinguished Research in Tumor Immunology.

2 Sep 2011

Men reluctant to use sunscreen- survey

A new survey claims that less than half of men use sunscreen of at least factor 15 to protect their skin from damage.

30 Aug 2011

Men worse than women at protecting their skin in the sun

Nearly 90 per cent of British adults admit their skin has been sunburnt - with almost half experiencing pain as result of being in the sun.

29 Aug 2011

Malignant News and Research

LC-MRM could provide better understanding of multiple myeloma drug resistance

Human gliomas release excess levels of glutamate and trigger seizures

Study pinpoints relationship between primary brain tumors and onset of epileptic seizures

Moffitt researchers employ LC-MRM to detect acquired multiple myeloma drug resistance

Aura's NanoSmart platform can enable earlier detection, treatment of cancers

Ohio Third Frontier grants to advance Philips Healthcare Global Advanced Imaging Innovation Center

New study to better understand relapsed medulloblastoma in children

Combination of blood tests and ROMA algorithm receives FDA clearance to treat ovarian cancer

SYSU, ASU collaborate to develop early and predictive diagnostics for colorectal cancer

Researchers use ultrasound to improve quality of blood stem cell transplant

Fujirebio Diagnostics receives FDA 510(k) clearance for Risk of Ovarian Malignancy Algorithm test

Biologists identify mechanism of H. pylori that damages DNA of gastric mucosal cells

Study sheds new light on the state of Europe's mental and neurological health

Asbestos related cancer risk rises after home renovations: Study

Researchers discover new genetic defect that predisposes people to leukemia, myelodysplasia

Neutrophils linked to growth and spread of cancer

Valproic acid may increase survival for brain tumor patients

CRI announces winners of 2011 Coley Award for distinguished research in tumor immunology

Men reluctant to use sunscreen- survey

Men worse than women at protecting their skin in the sun

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