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Local anesthetic drug not linked to reduction in opioid use, complications after knee surgery

Contrary to what some studies may suggest, the local anesthetic drug, liposomal bupivacaine, did not reduce in-hospital opioid prescriptions or opioid-related complications in patients who received the drug during total knee replacement surgery as part of a multimodal approach to manage postsurgical pain, finds a new study published in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists.

22 May 2018

Treg infusions show promise in slowing progression of ALS

Recent research from Houston Methodist Hospital showed that a new immunotherapy was safe for patients with ALS and also revealed surprising results that could bring hope to patients who have this relentlessly progressive and fatal disease.

21 May 2018

Researchers reveal mechanisms of periodic paralysis in people with rare genetic disorder

A rare genetic disorder in which people are suddenly overcome with profound muscle weakness is caused by a hole in a membrane protein that allows sodium ions to leak across cell membranes, researchers at the University of Washington School of Medicine in Seattle have found.

21 May 2018

Intelligent brains possess fewer neuronal connections, finds study

The more intelligent a person, the fewer connections there are between the neurons in his cerebral cortex. This is the result of a study conducted by neuroscientists working with Dr Erhan Genç and Christoph Fraenz at Ruhr-Universität Bochum; the study was performed using a specific neuroimaging technique that provides insights into the wiring of the brain on a microstructural level.

17 May 2018

Microglia may play key role in slowing progression of prion diseases, research suggests

Prion diseases are slow degenerative brain diseases that occur in people and various other mammals. No vaccines or treatments are available, and these diseases are almost always fatal. Scientists have found little evidence of a protective immune response to prion infections.

17 May 2018

Pfizer announces Phase 3 study results of LYRICA Oral Solution CV for pediatric epilepsy patients

Pfizer Inc. announced today positive top-line results of a Phase 3 study examining the use of LYRICA® Oral Solution CV as adjunctive therapy for partial onset seizures in pediatric epilepsy patients one month to less than four years of age.

17 May 2018

New study reveals the extent of brain damage due to elevated homocysteine

The amino acid homocysteine occurs naturally in the human body, generated as a byproduct of methionine metabolism.

17 May 2018

UC San Diego scientists discover gene that helps prevent neurodegenerative diseases

Scientists know that faulty proteins can cause harmful deposits or "aggregates" in neurological disorders such as Alzheimer's and Parkinson's disease. Although the causes of these protein deposits remain a mystery, it is known that abnormal aggregates can result when cells fail to transmit proper genetic information to proteins.

16 May 2018

Musician Huey Lewis's struggle shines spotlight on Ménière's disease

The recent news revealing musician Huey Lewis's struggles with Ménière's disease has shined a spotlight on the neurological disorder. The symptoms, which include unpredictable bouts of dizziness, hearing loss and ringing in the ears, may get progressively worse over time and can greatly interfere with work, driving and daily activities.

16 May 2018

Study uncovers mechanism underlying brain malformation linked to severe epilepsy

One of the most frequent causes of drug-resistant epilepsy, considered a difficult disease to control, is a brain malformation known as focal cortical dysplasia.

16 May 2018

Research could help mental health professionals to better treat patients with psychoses

Psychotic disorders often are severe and involve extreme symptoms such as delusions or hallucinations in which people lose their sense of reality.

16 May 2018

Lack of insurance exposes blind spots in vision care

Every day, a school bus drops off as many as 45 children at a community eye clinic on Chicago's South Side. Many of them are referred to the clinic after failing vision screenings at their public schools.

15 May 2018

Snorers may have extensive tissue damage in nerves and muscles of the soft palate

People who snore may have extensive tissue damage in the nerves and muscles of the soft palate. This can in turn create problems with swallowing and contribute to development of sleep apnea.

14 May 2018

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

A decay of brain function is a hallmark of Parkinson's disease and dementia with Lewy bodies, or DLB. Specifically, cognitive dysfunction defines DLB, and nearly eight of every 10 Parkinson's patients develop dementia.

11 May 2018

Stops and starts in CIN activity may be a mechanism for controlling animals’ response to unexpected stimuli

Changing our behavior based on unexpected cues from our environment is an essential part of survival. The ability to drop what you're doing when circumstances demand it could mean the difference between avoiding a speeding vehicle or getting hit by it.

10 May 2018

Using opioid-sparing pain management techniques to better prevent addiction and abuse

Over 2 million people each year switch to persistent opioid use after surgery, and nearly half of all U.S. opioid overdose deaths involve a prescription opioid.

10 May 2018

Scientists successfully graft neural precursor cells into spinal cords of syngeneic pigs with no immunosuppression

A major hurdle to using neural stem cells derived from genetically different donors to replace damaged or destroyed tissues, such as in a spinal cord injury, has been the persistent rejection of the introduced material, necessitating the use of complex drugs and techniques to suppress the host's immune response.

10 May 2018

Nerve News and Research

Local anesthetic drug not linked to reduction in opioid use, complications after knee surgery

Treg infusions show promise in slowing progression of ALS

Researchers reveal mechanisms of periodic paralysis in people with rare genetic disorder

Intelligent brains possess fewer neuronal connections, finds study

Microglia may play key role in slowing progression of prion diseases, research suggests

Pfizer announces Phase 3 study results of LYRICA Oral Solution CV for pediatric epilepsy patients

New study reveals the extent of brain damage due to elevated homocysteine

UC San Diego scientists discover gene that helps prevent neurodegenerative diseases

Musician Huey Lewis's struggle shines spotlight on Ménière's disease

Study uncovers mechanism underlying brain malformation linked to severe epilepsy

Research could help mental health professionals to better treat patients with psychoses

Lack of insurance exposes blind spots in vision care

Snorers may have extensive tissue damage in nerves and muscles of the soft palate

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

Stops and starts in CIN activity may be a mechanism for controlling animals’ response to unexpected stimuli

Using opioid-sparing pain management techniques to better prevent addiction and abuse

Scientists successfully graft neural precursor cells into spinal cords of syngeneic pigs with no immunosuppression

Study: Different strains of same protein may contribute to different Parkinson's-related brain disorders

Study finds neuroinflammation in spinal cord, nerve roots of patients with chronic sciatica

Mepivacaine is found to be an effective spinal anesthetic for knee replacement surgery

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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