Protein C News and Research

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Novel technique could speed up the development of peptide-based drugs against cancer

Researchers at the University at Buffalo have devised two new ways of "stapling" peptide helices to prevent these medically important molecules from losing their shape and degrading in the presence of enzymes.

9 Feb 2011

Urocortin system plays central role in regulating stress responses

Post-traumatic stress disorder can affect soldiers after combat or ordinary people who have undergone harrowing experiences. Of course, feelings of anxiety are normal and even desirable - they are part of what helps us survive in a world of real threats. But no less crucial is the return to normal - the slowing of the heartbeat and relaxation of tension - after the threat has passed.

9 Feb 2011

Scientists develop novel technique to detect disordered protein folding

A team of scientists from The Scripps Research Institute and the University of California, San Diego have developed a novel technique to observe previously unknown details of how folded structures are formed from an intrinsically disordered protein.

9 Feb 2011

Vical announces issuance of US patent for HSV-2 vaccine

Vical Incorporated announced today the issuance of U.S. Patent No. 7,879,339, assigned to Vical and the University of Washington, covering DNA vaccines for herpes simplex virus type 2.

9 Feb 2011

Physician offers tips to kick-off heart disease and its risk factors

The health statistics are heart-stopping for Hispanic communities: the leading cause of death among both Hispanic men and women is cardiovascular disease.

9 Feb 2011

New study shows eggs are 14% lower in cholesterol

According to new nutrition data from the United States Department of Agriculture's Agricultural Research Service, eggs are lower in cholesterol than previously thought.

8 Feb 2011

Mysteries of the hibernating heart

Hibernating, it turns out, is much more complicated than one might think.

8 Feb 2011

New DGA urge Americans to reduce sodium intake, consume walnuts for 'good' fat

The 2010 U.S. Dietary Guidelines for Americans urge Americans to reduce their sodium intake, replace saturated and trans fats with the "good" fats and to lower cholesterol consumption.

8 Feb 2011

Scientists develop low cost, nanometer-sized drug to treat chronic wounds

A low cost, nanometer-sized drug to treat chronic wounds, such as diabetic foot ulcers or burns, has been developed by a group of scientists from the Hebrew University of Jerusalem, Harvard Medical School and others in the U.S. and Japan.

8 Feb 2011

How cocoa in chocolate reduces risk of heart disease

In time for the chocolate-giving and chocolate-noshing fest on Valentine's Day, scientists are reporting discovery of how this treat boosts the body's production of high-density lipoprotein cholesterol (HDL) - the "good" form of cholesterol that protects against heart disease.

8 Feb 2011

Single molecule FRET techniques combined with wavelet transforms give new view of AMPA receptor

A digital signal processing technique long used by statisticians to analyze data is helping Houston scientists understand the roots of memory and learning, Alzheimer's and Parkinson's diseases and stroke.

8 Feb 2011

Ansaris receives milestone payment for identification of kinase-related compound for cancer, autoimmune diseases

Ansaris announced today that it has received a milestone payment for the successful identification of a kinase-related compound under its drug discovery collaboration with Ono Pharmaceutical Co., Ltd. Ono will initiate the preclinical study of the identified compound. This collaboration between Ansaris and Ono was established to focus on the discovery of kinase-related compounds for the treatment of cancer, inflammatory and autoimmune diseases.

8 Feb 2011

Elan 2010 total revenue increases 5% to $1,169.7 million

Elan Corporation, plc today reported its fourth quarter and full-year 2010 financial results and provided financial guidance for 2011.

8 Feb 2011

Almac opens analytical facility at new 240,000 sq. ft. North American Headquarters

Almac's new 240,000 sq. ft. North American Headquarters, built on 40 acres in Souderton, PA, north of Philadelphia is part of the Almac Group's integrated services solutions strategy. The new facility delivers full-service, integrated clinical packaging, drug supply management and technology solutions to pharmaceutical and biotech clients.

8 Feb 2011

TREK1 activity offers a key target for fluoxetine and other antidepressant drugs

Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy's Lawrence Berkeley National Laboratory and the University of California, Berkeley have identified a means by which fluoxetine, the active ingredient in Prozac, suppresses the activity of the TREK1 potassium channel.

8 Feb 2011

Transition reports second quarter 2011 net income of $24.28M vs. $6.05M net loss for second quarter 2010

Transition Therapeutics Inc., a product-focused biopharmaceutical company developing therapeutics for disease indications with large markets, today announced its financial results for the quarter ended December 31, 2010.

8 Feb 2011

Researchers develop new method for drug discovery using math to combat HIV, other diseases

Using mathematical concepts, Princeton researchers have developed a method of discovering new drugs for a range of diseases by calculating which physical properties of biological molecules may predict their effectiveness as medicines.

8 Feb 2011

Munich research team provides promising alternative to DNA-based procedures

Defects in the genome are the cause of many diseases. Gene therapy - direct replacement of mutant genes by intact DNA copies - offers a means of correcting such defects. Now a research team based at the Medical Center of the University of Munich, and led by Privatdozent Dr. Carsten Rudolph, has taken a new approach that avoids DNA delivery.

8 Feb 2011

Two new sources of soybean may replace fish meal in weanling pig diets

Two new sources of soybean meal are capturing attention throughout the country. University of Illinois research indicates that fermented soybean meal and enzyme-treated soybean meal may replace fish meal in weanling pig diets.

7 Feb 2011

Researchers identify CHK1 protein may serve as treatment target for neuroblastoma

After analyzing hundreds of proteins produced by the DNA of tumor cells, researchers have identified one protein that may be central to a new treatment for the often-fatal childhood cancer neuroblastoma. Oncologists hope to translate the finding into pediatric clinical trials of a drug that blocks the protein's activity.

7 Feb 2011

Protein C News and Research

Novel technique could speed up the development of peptide-based drugs against cancer

Urocortin system plays central role in regulating stress responses

Scientists develop novel technique to detect disordered protein folding

Vical announces issuance of US patent for HSV-2 vaccine

Physician offers tips to kick-off heart disease and its risk factors

New study shows eggs are 14% lower in cholesterol

Mysteries of the hibernating heart

New DGA urge Americans to reduce sodium intake, consume walnuts for 'good' fat

Scientists develop low cost, nanometer-sized drug to treat chronic wounds

How cocoa in chocolate reduces risk of heart disease

Single molecule FRET techniques combined with wavelet transforms give new view of AMPA receptor

Ansaris receives milestone payment for identification of kinase-related compound for cancer, autoimmune diseases

Elan 2010 total revenue increases 5% to $1,169.7 million

Almac opens analytical facility at new 240,000 sq. ft. North American Headquarters

TREK1 activity offers a key target for fluoxetine and other antidepressant drugs

Transition reports second quarter 2011 net income of $24.28M vs. $6.05M net loss for second quarter 2010

Researchers develop new method for drug discovery using math to combat HIV, other diseases

Munich research team provides promising alternative to DNA-based procedures

Two new sources of soybean may replace fish meal in weanling pig diets

Researchers identify CHK1 protein may serve as treatment target for neuroblastoma

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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