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Carbon monoxide used to protect mouse nerve cells from damage

Researchers at Johns Hopkins have shown that brain damage was reduced by as much as 62.2 percent in mice who inhale low amounts of carbon monoxide after an induced stroke.

15 Dec 2008

Continuous positive airway pressure improves sleeping glucose levels in type 2 diabetics with obstructive sleep apnea

A study in the Dec. 15 issue of the Journal of Clinical Sleep Medicine suggests that screening type 2 diabetes patients for obstructive sleep apnea (OSA) and treating those who have OSA with continuous positive airway pressure (CPAP) therapy could improve the management of their hyperglycemia and might favorably influence their long-term prognosis.

15 Dec 2008

Intervention in infants with cystic fibrosis key to slowing progression

Early detection of lung disease in cystic fibrosis (CF), combined with aggressive treatment in infants, may be the key to controlling the progression of the disease, according to a recent study.

5 Dec 2008

Idiopathic pulmonary fibrosis linked to heart attacks

Patients with idiopathic pulmonary fibrosis (IPF) are three times as likely to experience severe coronary events - including heart attacks - than people without the disease, according to a recent study that analyzed the risk of cardiovascular disease in nearly 1,000 patients with IPF and more than 3,500 matched controls.

5 Dec 2008

Call for greater caution in prescribing inhaled corticosteroids to COPD sufferers

Lung disease experts at Johns Hopkins are calling for physicians to show much greater caution in prescribing inhaled corticosteroid drugs for people with chronic obstructive pulmonary disease after finding evidence that the widely used anti-inflammatory medications increase the risk of pneumonia by a full third.

25 Nov 2008

Long-term use of a macrolide antibiotic reduce COPD exacerbations, raise questions

Long-term use of a macrolide antibiotic may reduce the frequency of exacerbations in patients with moderate to severe chronic obstructive pulmonary disease (COPD) by as much as 35 percent, according to a London-based study.

21 Nov 2008

Children born four months before height of cold and flu season have a greater risk of developing childhood asthma

It is said that timing is everything, and that certainly appears to be true for autumn infants.

21 Nov 2008

Isoflurane induces Alzheimer's-associated changes in mouse brains

For the first time researchers have shown that a commonly used anesthetic can produce changes associated with Alzheimer's disease in the brains of living mammals, confirming previous laboratory studies.

12 Nov 2008

New blood test identifies sickest heart failure patients in ER

A new blood test identifies the sickest heart failure patients better than tests now used in emergency departments, researchers reported at the American Heart Association's Scientific Sessions 2008. Results of the Mid-Regional pro-Adrenomedullin (proADM) versus BNP and NTproBNP as Prognosticator in Heart Failure Patients: Results of the BACH Multinational Trial were presented as a late-breaking clinical trial.

11 Nov 2008

A probiotic bacterium reduces hospital infections

A probiotic bacterium, Lactobacillus plantarum 299, has been used to out-compete the dangerous bacteria that cause respiratory illness in ventilated patients.

6 Nov 2008

Researchers look at benefits and applications of medical simulation

Emergency medicine physicians and simulation experts from Rhode Island Hospital discuss the benefits of advanced medical simulation in five manuscripts appearing in the November 2008 issue of Academic Emergency Medicine (now available online).

4 Nov 2008

Bisphosphonates for osteoporosis increase risk for heart problems

People who take bisphosphonates for osteoporosis may be at risk for serious atrial fibrillation (AF), or irregular heartbeats, according to a new study.

27 Oct 2008

Healing process found to backfire in idiopathic pulmonary fibrosis patients

A mechanism in the body which typically helps a person heal from an injury, may actually be causing patients with idiopathic pulmonary fibrosis (IPF) to get worse, researchers at the National Institute of Environmental Health Sciences (NIEHS), a part of the National Institutes of Health (NIH), and their collaborators have found.

27 Oct 2008

Human rhinovirus found to manipulate genes

Sneezing, runny nose and chills? You might blame the human rhinovirus (HRV), which causes 30 to 50 percent of common colds. But in reality, it's not the virus itself but HRV's ability to manipulate your genes that is the true cause of some of the most annoying cold symptoms.

26 Oct 2008

Simple gene-based blood test, quicker, more accurate evaluation for cystic fibrosis

Researchers at National Jewish Health have identified a simple gene-based blood test that more accurately and quickly measures cystic fibrosis patients' response to therapy than current tests.

26 Oct 2008

Even minimally symptomatic obstructive sleep apnea increases cardiovascular risk

People with even minimally symptomatic obstructive sleep apnea (OSA) may be at increased risk for cardiovascular disease because of impaired endothelial function and increased arterial stiffness, according to a study from the Oxford Centre for Respiratory Medicine in the UK.

26 Oct 2008

Aires Pharmaceuticals signs license agreement with NIH

Aires Pharmaceuticals Inc. today announced the signing of an exclusive license agreement with the U.S. National Institutes of Health for the patented use of a nitric oxide prodrug to treat cardiopulmonary conditions.

22 Oct 2008

Prolonging the withdrawal of life support in the ICU affects family satisfaction with care

Clinicians in the intensive care unit (ICU) often care for patients who are on several life support measures at once. When such a patient is dying and the decision is reached to withdraw life support, these clinicians may make an imperfect compromise in seeking to balance the complex needs of the patient and the patient's family - they may remove the life support measures one at a time over a period of days, rather than withdrawing all at once.

15 Oct 2008

Quark Pharmaceuticals' siRNAs examined alone and in xombination with chemotherapy

Quark Pharmaceuticals, Inc. has announced that the journal Cancer Research published results on efficacy of siRNA targeting its proprietary target gene against non-small cell lung cancer (NSCLC) in the edition dated October 1, 2008.

12 Oct 2008

Ginkgo biloba may prevent brain cell damage after a stroke

Working with genetically engineered mice, researchers at Johns Hopkins have shown that daily doses of a standardized extract from the leaves of the ginkgo tree can prevent or reduce brain damage after an induced stroke.

12 Oct 2008

Critical Care News and Research

Carbon monoxide used to protect mouse nerve cells from damage

Continuous positive airway pressure improves sleeping glucose levels in type 2 diabetics with obstructive sleep apnea

Intervention in infants with cystic fibrosis key to slowing progression

Idiopathic pulmonary fibrosis linked to heart attacks

Call for greater caution in prescribing inhaled corticosteroids to COPD sufferers

Long-term use of a macrolide antibiotic reduce COPD exacerbations, raise questions

Children born four months before height of cold and flu season have a greater risk of developing childhood asthma

Isoflurane induces Alzheimer's-associated changes in mouse brains

New blood test identifies sickest heart failure patients in ER

A probiotic bacterium reduces hospital infections

Researchers look at benefits and applications of medical simulation

Bisphosphonates for osteoporosis increase risk for heart problems

Healing process found to backfire in idiopathic pulmonary fibrosis patients

Human rhinovirus found to manipulate genes

Simple gene-based blood test, quicker, more accurate evaluation for cystic fibrosis

Even minimally symptomatic obstructive sleep apnea increases cardiovascular risk

Aires Pharmaceuticals signs license agreement with NIH

Prolonging the withdrawal of life support in the ICU affects family satisfaction with care

Quark Pharmaceuticals' siRNAs examined alone and in xombination with chemotherapy

Ginkgo biloba may prevent brain cell damage after a stroke

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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