Precision Medicine News and Research

RSS

Tepnel Pharma Services uses Hologic’s Invader Plus technology to offer genotyping, CNV service

Tepnel Pharma Services, a division of Hologic, Inc., is now using Hologic’s proprietary Invader and Invader Plus technology as part of its Molecular Genetic Services offering, enabling it to offer customers a more cost effective and high throughput genotyping and copy number variation service.

From Hologic, Inc. 15 Oct 2013

Results announced for Phase II PRECEDENT trial of vintafolide for treatment of platinum-resistant ovarian cancer

Merck, known as MSD outside the United States and Canada, (NYSE: MRK) and Endocyte, Inc. (NASDAQ: ECYT) today announced the online publication of results from the randomized Phase II PRECEDENT trial for vintafolide (MK-8109/EC145), an investigational folate small molecule drug conjugate (SMDC), in the Journal of Clinical Oncology (JCO), the official journal of the American Society of Clinical Oncology.

15 Oct 2013

Researchers create online database of disease genes that could be targeted with drugs

Researchers at Washington University School of Medicine in St. Louis have created a massive online database that matches thousands of genes linked to cancer and other diseases with drugs that target those genes.

14 Oct 2013

Super-enhancers could play important roles in disease diagnostics and therapeutics

Having recently discovered a set of powerful gene regulators that control cell identity in a few mouse and human cell types, Whitehead Institute scientists are now showing that these regulators-which they named "super-enhancers"-act across a vast array of human cell types and are enriched in mutated regions of the genome that are closely associated with a broad spectrum of diseases.

11 Oct 2013

Suppression of mitochondria: A dominant feature of diabetic kidney disease

Researchers at the University of California, San Diego School of Medicine have identified 13 metabolites - small molecules produced by cellular metabolism - that are significantly different in patients with diabetes and chronic kidney disease compared to healthy controls.

11 Oct 2013

New smartphone app puts genetic information in the hands of people

Until now, understanding and using genetic information has depended on the scientists and doctors who do the testing. No longer.

9 Oct 2013

Researchers use ARRAYit Microarray Platform to discover important biomarkers

ARRAYit Corporation reports today that researchers at the National Institutes of Health (NIH), National Cancer Institute (NCI) and Northeastern University have used the ARRAYit Microarray Platform to discover biomarkers important in the treatment of prostate cancer.

8 Oct 2013

Experimental Therapeutics, Debiopharm join to develop oral small molecules targeting new class of epigenetic modulators

The Agency for Science, Technology and Research (A*STAR)'s Experimental Therapeutics Centre (ETC), a center of excellence to advance and accelerate drug discovery in Singapore, and Debiopharm Group™ (Debiopharm), the Swiss-based global biopharmaceutical company that focuses on the development of prescription drugs that target unmet medical needs including oncology as well as companion diagnostics, today announced the signature of an exclusive research collaboration to develop oral small molecules targeting new class of epigenetic modulators.

7 Oct 2013

Study shows precision medicine provides better treatment options for mentally ill person

A multidisciplinary team led by a geneticist and psychiatrist from Cold Spring Harbor Laboratory's (CSHL) Stanley Institute for Cognitive Genomics today publish a paper providing a glimpse of both the tremendous power and the current limitations of what is sometimes called "precision medicine."

5 Oct 2013

'Personalised medicine': Topic of free public lecture at the University of Greenwich

'Personalised medicine' is the topic of a free public lecture at the University of Greenwich. Personalised medicine, or precision medicine, as it is sometimes known, is a key goal for 21st century healthcare. Currently, many medicines are either ineffective or unsafe in certain patient populations, whereas the aim for personalised medicine is to target the right treatment to the right patient group.

5 Oct 2013

Findings may result in better management of chronic depression

Virginia Commonwealth University has received a $3 million grant from the National Institute of Mental Health to study key molecular markers found in DNA that predict chronic depression.

2 Oct 2013

Laboratory testing kit that estimates risk of breast cancer relapse gets FDA approval

A laboratory testing kit that estimates the risk of breast cancer relapse in spite of anti-hormone treatment has received approval from the U.S. Food and Drug Administration.

2 Oct 2013

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

A groundbreaking study of nearly 2,300 extremely obese diabetes patients, led by the Translational Genomics Research Institute, has identified genes associated with unhealthy liver function.

2 Oct 2013

Standoff between a mutated gene and normal counterpart keeps certain cancer cells alive

What keeps leukemia cells alive almost forever, able to continue dividing endlessly and aggressively? New research at the Weizmann Institute suggests that, in around a quarter of all leukemias, the cancer cells rely on an internal "balance of terror" to keep going.

1 Oct 2013

Four Geisinger Health System researchers receive $25M grant to initiate ClinGen Project

Four Geisinger Health System researchers have taken center stage in the national arena of genomics thanks to new funding from the National Human Genome Research Institute (NHGRI), an arm of the U.S. National Institutes of Health (NIH).

27 Sep 2013

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Rhythm announced today the initiation of the first of a series of clinical trials with RM-493, the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of obesity in individuals with a genetic deficiency in the MC4R pathway.

24 Sep 2013

Genetics in Medicine's October 2013 issue details solutions for integrating genomic data into EHR

Genetic tests can now tell us whether we are at increased risk of various cancers, heart or kidney disease, asthma and a number of other conditions.

20 Sep 2013

Human breast tumors transplant could be valuable tools in search for better treatments

Breast cancer that spreads to other organs is extremely difficult to treat. Doctors can buy patients time, but a cure remains elusive. Now, researchers at Washington University School of Medicine in St. Louis have shown that human breast tumors transplanted into mice are excellent models of metastatic cancer and could be valuable tools in the search for better treatments.

20 Sep 2013

Ventana, Boehringer Ingelheim to develop companion diagnostic tests for oncology programs

Ventana Medical Systems, Inc., a member of the Roche Group, and Boehringer Ingelheim announced today that they have entered into an agreement to collaborate on the development of companion diagnostic tests for Boehringer Ingelheim oncology programs.

19 Sep 2013

Researchers discover why multiple myeloma recurs after initially effective treatment

Researchers have discovered why multiple myeloma, a difficult to cure cancer of the bone marrow, frequently recurs after an initially effective treatment that can keep the disease at bay for up to several years.

19 Sep 2013

Precision Medicine News and Research

Tepnel Pharma Services uses Hologic’s Invader Plus technology to offer genotyping, CNV service

Results announced for Phase II PRECEDENT trial of vintafolide for treatment of platinum-resistant ovarian cancer

Researchers create online database of disease genes that could be targeted with drugs

Super-enhancers could play important roles in disease diagnostics and therapeutics

Suppression of mitochondria: A dominant feature of diabetic kidney disease

New smartphone app puts genetic information in the hands of people

Researchers use ARRAYit Microarray Platform to discover important biomarkers

Experimental Therapeutics, Debiopharm join to develop oral small molecules targeting new class of epigenetic modulators

Study shows precision medicine provides better treatment options for mentally ill person

'Personalised medicine': Topic of free public lecture at the University of Greenwich

Findings may result in better management of chronic depression

Laboratory testing kit that estimates risk of breast cancer relapse gets FDA approval

Genetic study helps identify obese diabetes patients who are at risk of developing NAFLD

Standoff between a mutated gene and normal counterpart keeps certain cancer cells alive

Four Geisinger Health System researchers receive $25M grant to initiate ClinGen Project

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Genetics in Medicine's October 2013 issue details solutions for integrating genomic data into EHR

Human breast tumors transplant could be valuable tools in search for better treatments

Ventana, Boehringer Ingelheim to develop companion diagnostic tests for oncology programs

Researchers discover why multiple myeloma recurs after initially effective treatment

Editorial Focus eBook - Proteomics eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

Applications Engineer

Latest News