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Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

A new study by Weill Cornell Medicine and Cornell University has come up with more explanations of how gut microbes communicate with the brain neurons. The study, published in the journal Nature on October 23, 2019, examined the brains of mouse models and found that when the gut microbiome is significantly reduced, there are changes in gene expression in the brain’s microglial cells.

24 Oct 2019

Genetically definable subgroups of cancers sensitive to treatment

Precision oncology aims to use genetic features of a patient's tumor to tailor anti-cancer therapy. DNA mutations in a drug target have provided a number of therapeutic opportunities; however, there are many cancer types that do not have obvious targetable mutations.

24 Oct 2019

High-salt diet may trigger dementia

We’ve all heard that taking too much salt can damage your blood vessels, and now a new study published in the journal Nature on October 23, 2019, says it’s true – a diet rich in salt reduces the levels of nitric oxide, which in turn alters the tau protein within the neuron, triggering a fall in cognitive processing by the brain.

24 Oct 2019

New study finds gaps in treatment for patients with chronic kidney disease

Millions of Canadians living with chronic kidney disease (CKD) may be going without critical testing from their primary care practitioners that would give them a good idea of the severity of the disease so they could intervene earlier with more appropriate care, according to a new study.

24 Oct 2019

Flu antibody could be a key to better treatments for severe flu disease

Researchers have found an antibody that protects mice against a wide range of lethal influenza viruses, according to a study from Washington University School of Medicine in St. Louis, Icahn School of Medicine at Mount Sinai in New York City, and Scripps Research in La Jolla, Calif.

24 Oct 2019

Protein mutation that causes inflammatory bowel diseases becomes dysfunctional

A new study led by researchers at St. Michael's Hospital and the Princess Margaret Cancer Centre in Canada and Zhejiang University School of Medicine in China has uncovered why a protein mutation that causes inflammatory bowel diseases is dysfunctional.

24 Oct 2019

Bias, workplace harassment and hostility can cause minority doctors to change practices

Despite the dire need for primary health care providers in California's Central Valley, workplace discrimination and harassment can cause them to change practices or leave the region entirely.

24 Oct 2019

Rigorous enforcement, flavor restriction policies have potential to curb youth tobacco use

Restricting youth access to flavored tobacco products holds the promise of reducing their overall tobacco use, according to a new study in the American Journal of Preventive Medicine, published by Elsevier.

24 Oct 2019

Higher levels of chemicals in mothers' system during pregnancy linked to lower IQ in children

Exposure during the first trimester of pregnancy to mixtures of suspected endocrine-disrupting chemicals found in consumer products is related to lower IQ in children by age 7, according to a study by researchers at the Icahn School of Medicine at Mount Sinai and Karlstad University, Sweden, published in Environment International in October.

24 Oct 2019

Study aims to learn more about silent infarction, cognitive decline linked to silent stroke

Can you have a stroke and not know it? Unfortunately, yes. It is a phenomenon called a silent stroke or, more formally, a silent cerebral infarction. Investigators at the University of Alabama at Birmingham and Stanford University want to learn more about silent strokes and their role in brain health, including dementia.

24 Oct 2019

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

The survival of patients with pediatric acute lymphoblastic leukemia (ALL) has significantly improved in the last several decades. However, novel strategies to identify cases that are likely to respond poorly to treatment are still needed.

24 Oct 2019

NIAID-supported clinical trial begins at four Vaccine and Treatment Evaluation Units

A clinical trial in which healthy adults will be deliberately infected with influenza virus under carefully controlled conditions is recruiting volunteers at four Vaccine and Treatment Evaluation Units (VTEUs) supported by NIH's National Institute of Allergy and Infectious Diseases.

24 Oct 2019

Researchers identify potential approach to stop growth of common brain tumor in children

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children.

24 Oct 2019

Universal influenza vaccine developed at Cornell is set for human clinical trials

A universal influenza vaccine with the potential to be longer lasting and more effective than commercially available vaccines is destined for human clinical trials, thanks to a $17.9 million grant from the National Institute of Allergy and Infectious Diseases.

24 Oct 2019

McMaster University research potentially offers new tool for assessing eating habits

Researchers at McMaster University have identified several chemical signatures, detectable in blood and urine, that can accurately measure dietary intake, potentially offering a new tool for physicians, dieticians and researchers to assess eating habits, measure the value of fad diets and develop health policies.

24 Oct 2019

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

A team of Gladstone scientists and their partners at Xyphos Biosciences, Inc. describe a new way of attacking cells infected by HIV in this week's issue of the journal Cell.

24 Oct 2019

Genetic variations linked to declines in blood oxygen levels during sleep identified

Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels during sleep. Low oxygen levels during sleep are a clinical indicator of the severity of sleep apnea, a disorder that increases the risk of heart disease, dementia, and death.

24 Oct 2019

Mayo Clinic study explores patient privacy in MRI research

Though identifying data typically are removed from medical image files before they are shared for research, a Mayo Clinic study finds that this may not be enough to protect patient privacy.

24 Oct 2019

Infant formula containing MFGM contributes to beneficial cognitive, respiratory health outcomes

Results from a clinical trial published today in the Journal of Pediatrics show infants who consume formula containing milk fat globule membrane (MFGM) -- a complex layer that normally surrounds fat in milk -- score higher in tests of cognitive, language and motor development by their first birthdays than infants consuming a milk-based formula that didn't contain MFGM.

24 Oct 2019

Vaccine for Lassa fever set to enter clinical testing in humans

There is currently no vaccine for the Lassa arenavirus, which causes Lassa fever. This hemorrhagic fever, endemic in West Africa, infects up to 300,000 people each year.

24 Oct 2019

Medicine News and Research

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

Genetically definable subgroups of cancers sensitive to treatment

High-salt diet may trigger dementia

New study finds gaps in treatment for patients with chronic kidney disease

Flu antibody could be a key to better treatments for severe flu disease

Protein mutation that causes inflammatory bowel diseases becomes dysfunctional

Bias, workplace harassment and hostility can cause minority doctors to change practices

Rigorous enforcement, flavor restriction policies have potential to curb youth tobacco use

Higher levels of chemicals in mothers' system during pregnancy linked to lower IQ in children

Study aims to learn more about silent infarction, cognitive decline linked to silent stroke

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

NIAID-supported clinical trial begins at four Vaccine and Treatment Evaluation Units

Researchers identify potential approach to stop growth of common brain tumor in children

Universal influenza vaccine developed at Cornell is set for human clinical trials

McMaster University research potentially offers new tool for assessing eating habits

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

Genetic variations linked to declines in blood oxygen levels during sleep identified

Mayo Clinic study explores patient privacy in MRI research

Infant formula containing MFGM contributes to beneficial cognitive, respiratory health outcomes

Vaccine for Lassa fever set to enter clinical testing in humans

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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