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Stents for blocked brain arteries may not be as successful in prolonging survival as believed: Study

A study out this Wednesday says that insertion of an artery-opening device called a stent into the brain to improve blood flow to prevent a second stroke may do more harm than managing high-risk patients with drugs and lifestyle changes. Blocked brain arteries caused by the build-up of fatty deposits called plaque account for more than 50,000 of the 795,000 strokes occurring in the United States each year. Stroke is the fourth-leading cause of death and a leading cause of disability in the United States.

8 Sep 2011

Medicare fraud investigation nets 91 offenders

A nationwide sweep on lawbreakers has charged 91 people - including doctors and other medical professionals - with participating in Medicare fraud schemes involving $295 million in false billing.

8 Sep 2011

Breast-conservation therapy and mastectomy provide similar survival rates for early-stage breast cancer

Young women with early-stage breast cancer have similar survival rates with a lumpectomy and radiation treatment, known as breast-conservation therapy, as with mastectomy, a new study conducted at the University of Maryland has found. The results of the analysis of nearly 15,000 patients listed in a nationwide cancer registry will be presented at the 2011 Breast Cancer Symposium to be held Sept. 8-11 in San Francisco.

8 Sep 2011

Aggressive medical management better than stenting for prevention of recurrent stroke

Patients at a high risk for a second stroke who received intensive medical treatment had fewer strokes and deaths than patients who received a brain stent in addition to the medical treatment, a large nationwide clinical trial has shown. The investigators published the results in today's online first edition of the New England Journal of Medicine.

8 Sep 2011

Researchers identify bouncer protein that plays a vital role in RA prevention

Researchers at Northwestern University Feinberg School of Medicine have discovered why the immune cells of people with rheumatoid arthritis become hyperactive and attack the joints and bones. The immune cells have lost their bouncer, the burly protein that keeps them in line the same way a bouncer in a nightclub controls rowdy patrons.

8 Sep 2011

'Chaperone' protein may play a critical role in pathogenesis of heart failure

Researchers at Mount Sinai School of Medicine have identified a new drug target that may treat and/or prevent heart failure. The team evaluated failing human and pig hearts and discovered that SUMO1, a so-called "chaperone" protein that regulates the activity of key transporter genes, was decreased in failing hearts.

8 Sep 2011

Scientists discover backup circuits in cetuximab-resistant cancer cells

Scientists at Dana-Farber Cancer Institute and colleagues overseas have discovered a pair of backup circuits in cancer cells that enable the cells to dodge the effect of a widely used cancer drug.

8 Sep 2011

Intensive medical treatment more effective in preventing second stroke than stenting

People who received intensive medical treatment following a first stroke had fewer second episodes and were less likely to die than people who received brain stents in addition to medical treatment, according to a new report in the New England Journal of Medicine, to be published online Sept. 7.

8 Sep 2011

Researchers identify new drug target for heart failure

8 Sep 2011

ATA announces five recipients of 2011 thyroid cancer research grants

The American Thyroid Association (ATA) announced the five recipients of its 2011 research grants, each of whom will receive up to $25,000 annually for up to two years. Three of the five recipients were awarded special ATA ThyCa grants for research projects that focus on thyroid cancer. These grants are funded by ThyCa: Thyroid Cancer Survivors, Inc.

8 Sep 2011

Pharnext puts together €2.5M to fund development of Pleodrug for Charcot-Marie-Tooth disease

Pharnext SAS, a biopharmaceutical company specializing in the development of innovative treatments based on Pleotherapy for severe neurological diseases, today announced that it has put together a €2.5 million round of financing (corresponding to a pre-money company valuation of €60 million).

8 Sep 2011

Study: Aerobic physical activity linked to reduced risk of dementia

Any exercise that gets the heart pumping may reduce the risk of dementia and slow the condition's progression once it starts, reported a Mayo Clinic study published this month in Mayo Clinic Proceedings.

8 Sep 2011

Exercise, intervention may help individuals with peripheral arterial disease

Peripheral arterial disease, or PAD, is a common condition affecting 12-20 percent of Americans age 65 and older that may be a signal of future heart attack and stroke-and many with the disease may be unaware they have it, says the Society of Interventional Radiology.

8 Sep 2011

Adding azithromycin to usual daily treatment for COPD reduces acute exacerbations by 27%

Richard Casaburi, Ph.D., M.D., principal investigator at Los Angeles Biomedical Research Institute (LA BioMed), is co-author of a recent study that should help improve the condition for the millions of individuals who suffer from chronic obstructive pulmonary disease, better known as COPD.

8 Sep 2011

Experts to address crucial issues of pain management and disability health reform

Leading Australian and international medical experts will convene in Brisbane next week to address crucial areas of rehabilitation medicine, including health reform, barriers to rehabilitation healthcare services and pain management.

7 Sep 2011

Ardea Biosciences reports positive outcome from lesinurad End-of-Phase 2 meetings with FDA

Ardea Biosciences, Inc. announced that it has completed formal End-of-Phase 2 meetings with the U.S. Food and Drug Administration (FDA) and successfully reached agreement on the following key aspects of its proposed lesinurad Phase 3 development plan: the overall size and design of the planned Phase 3 clinical studies, the primary endpoints, the total safety database proposed for NDA filing, manufacturing plans for both drug substance and drug product, the preclinical toxicology program and the clinical pharmacology program.

7 Sep 2011

St. Jude Medical receives approval for CRT-D quadripolar pacing system in India

St. Jude Medical, Inc., a global medical device company, today announced the approval of the industry's first quadripolar pacing system for cardiac resynchronization therapy defibrillators (CRT-Ds) in India. The Promote Quadra CRT-D offers physicians the ability to more effectively and efficiently manage the ever-changing pacing needs of patients with heart failure.

7 Sep 2011

Researchers rethink fenretinide for prevention of oral cancer

Scientists on the cutting edge of biomedical research know that research is a process - a combination of successes and failures that inform the next step forward. However, for some researchers at The Ohio State University progress means taking a step back. Supported by the Ohio State University Center for Clinical and Translational Science (CCTS), these scientists are using failed and forgotten research to uncover future treatments for major health conditions as diverse as oral cancer and stroke.

7 Sep 2011

IBCRF awards TGen $50,000 to discover genetic origins of inflammatory breast cancer

The Inflammatory Breast Cancer Research Foundation (IBCRF) has awarded $50,000 to the Translational Genomics Research Institute (TGen) to discover the genetic origins of this rare and most deadly form of breast cancer.

7 Sep 2011

New bone marrow-derived stem cell therapy can benefit patients with degenerative disc disease

Neurosurgery researchers at UC Davis Health System have used a new, leading-edge stem cell therapy to promote the growth of bone tissue following the removal of cervical discs -- the cushions between the bones in the neck -- to relieve chronic, debilitating pain.

7 Sep 2011

Therapy News and Research

Stents for blocked brain arteries may not be as successful in prolonging survival as believed: Study

Medicare fraud investigation nets 91 offenders

Breast-conservation therapy and mastectomy provide similar survival rates for early-stage breast cancer

Aggressive medical management better than stenting for prevention of recurrent stroke

Researchers identify bouncer protein that plays a vital role in RA prevention

'Chaperone' protein may play a critical role in pathogenesis of heart failure

Scientists discover backup circuits in cetuximab-resistant cancer cells

Intensive medical treatment more effective in preventing second stroke than stenting

Researchers identify new drug target for heart failure

ATA announces five recipients of 2011 thyroid cancer research grants

Pharnext puts together €2.5M to fund development of Pleodrug for Charcot-Marie-Tooth disease

Study: Aerobic physical activity linked to reduced risk of dementia

Exercise, intervention may help individuals with peripheral arterial disease

Adding azithromycin to usual daily treatment for COPD reduces acute exacerbations by 27%

Experts to address crucial issues of pain management and disability health reform

Ardea Biosciences reports positive outcome from lesinurad End-of-Phase 2 meetings with FDA

St. Jude Medical receives approval for CRT-D quadripolar pacing system in India

Researchers rethink fenretinide for prevention of oral cancer

IBCRF awards TGen $50,000 to discover genetic origins of inflammatory breast cancer

New bone marrow-derived stem cell therapy can benefit patients with degenerative disc disease

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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