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Insight into brain mechanism that limits rewarding impact of cocaine

Research published by Cell Press in the January 12 issue of the journal Neuron provides fascinating insight into a newly discovered brain mechanism that limits the rewarding impact of cocaine. The study describes protective delayed mechanism that turns off the genes that support the development of addiction-related behaviors.

12 Jan 2012

First details of genetic alterations that fuel early T-cell precursor ALL

Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The findings from the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (PCGP) highlight a possible new strategy for treating patients with this more aggressive cancer.

12 Jan 2012

Excess salt stimulates production of adrenalin and causes hypertension

A review article by researchers at Boston University School of Medicine (BUSM) debunks the widely-believed concept that hypertension, or high blood pressure, is the result of excess salt causing an increased blood volume, exerting extra pressure on the arteries. Published online in the Journal of Hypertension, the study demonstrates that excess salt stimulates the sympathetic nervous system to produce adrenalin, causing artery constriction and hypertension.

12 Jan 2012

Drinking alcohol leads to release of endorphins in the brain

Drinking alcohol leads to the release of endorphins in areas of the brain that produce feelings of pleasure and reward, according to a study led by researchers at the Ernest Gallo Clinic and Research Center at the University of California, San Francisco.

12 Jan 2012

Two emergency medicine physicians create weapon against lethal war injury

Two emergency medicine physicians with wartime experience have developed a weapon against one rapidly lethal war injury.

12 Jan 2012

$Patients with hip fractures should be operated on within 48 hours of admission$

Patients with hip fractures should be operated on within 48 hours of admission

All patients with hip fractures should be fast-tracked through hospital emergency departments and operated on within 48 hours of admission, according to new consensus guidelines developed by UK experts in anaesthesia, orthopaedics, geriatrics and emergency medicine and published in the January issue of Anaesthesia.

12 Jan 2012

Chemotherapy drugs can lead to relapse of leukemia

The chemotherapy drugs required to push a common form of adult leukemia into remission may contribute to DNA damage that can lead to a relapse of the disease in some patients, findings of a new study suggest.

12 Jan 2012

Investing in Frontline Health Workers effective in saving lives of mothers, children

In the Huffington Post's "Impact" blog, Carolyn Miles, president and CEO of Save the Children, writes about the Frontline Health Workers Coalition's call on the U.S. government to train 250,000 new frontline health workers in developing countries, stating, "At a time when every dollar counts more than ever, the new Frontline Health Workers Coalition believes this focus is the most cost-effective way to save mothers' and children's lives around the world, address global health threats, and help advance strategic U.S. interests in a secure and prosperous world."

12 Jan 2012

UBM Medica's cancer care reference book now available online

UBM Medica's widely acclaimed and trusted cancer care reference book Cancer Management: A Multidisciplinary Approach, 14th edition, is now available online. This guide is designed to present important clinical information concisely, uniformly, and logically, emphasizing the natural history of the malignancy, screening and diagnosis, staging and prognosis, and treatment of cancers.

12 Jan 2012

DBS safe and effective for patients with advanced Parkinson's

Researchers from the University of Florida and 14 additional medical centers reported results today in the online version of The Lancet Neurology journal indicating that deep brain stimulation - also known as DBS - is effective at improving motor symptoms and quality of life in patients with advanced Parkinson's disease.

12 Jan 2012

USPTO issues patent to Unigene's peptide-based therapeutics for obesity

Unigene Laboratories, Inc., a leader in the design, delivery, manufacture and development of peptide-based therapeutics, today announced that it had been granted U.S. Patent No. 8,076,291 from the United States Patent and Trademark Office.

11 Jan 2012

Researchers identify mechanism that makes retinoblastoma so aggressive

New findings from the St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project (PCGP) have helped identify the mechanism that makes the childhood eye tumor retinoblastoma so aggressive. The discovery explains why the tumor develops so rapidly while other cancers can take years or even decades to form.

11 Jan 2012

Regular aspirin may not be good for all: Study

Researchers suggest that healthy individuals who take aspirin to prevent a heart attack or stroke could be doing more harm than good. An analysis of more than 100,000 patients, published in Archives of Internal Medicine, concluded the risk of internal bleeding was too high. The UK-led study said only people with a history of heart problems or stroke should take the tablets. Experts however added that any decision should be made with a doctor.

11 Jan 2012

Weight gain and other metabolic side effects of bipolar and schizophrenia drugs may be countered

A new study suggests that young people who are diagnosed with bipolar disorder and schizophrenia may be spared the side-effects of taking medication with the right diet and exercise program.

11 Jan 2012

Occasional marijuana use does not affect lung function: Study

A new study published in the Journal of the American Medical Association has shown that an occasional drag on marijuana does not appear to have long-term adverse effects on lung function.

11 Jan 2012

Collaborative behavioral management may be effective in reducing abuse among paroled marijuana users

A study from Rhode Island Hospital has found that collaborative behavioral management may be effective in reducing substance abuse among convicted marijuana users who are paroled. The findings have important implications for the management of a substantial proportion of the U.S. community correctional population.

11 Jan 2012

Swallowable endoscopic capsule may provide real time photographs of patient's insides

Researchers at Brigham and Women's Hospital (BWH) have successfully tested a controllable endoscopic capsule, inspired by science fiction, that has the ability to "swim" through the body and could provide clinicians with unprecedented control when photographing the inside of the human body.

11 Jan 2012

Oramed files provisional patent application with USPTO for combination diabetes therapy

Oramed Pharmaceuticals Inc., a developer of oral drug delivery systems, announced today that it has filed a provisional patent application with the United States Patent and Trademark Office for a combination therapy of its lead compound, ORMD-0801 in combination with its oral exenatide formulation, ORMD-0901. There is no such approved combination product available on the market today.

11 Jan 2012

TB screening, treatment program working to decrease caseload in Kenya

Al Jazeera examines how "[a] series of public-health campaigns, including more aggressive screening, have been credited with a drop in tuberculosis [TB] cases in Kenya" in this video report.

11 Jan 2012

Erlotinib better for treatment of non-small cell lung cancers

Researchers at Johns Hopkins have shown that DNA changes in a gene that drives the growth of a form of lung cancer can make the cancer's cells resistant to cancer drugs.

11 Jan 2012