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FDA accepts Salix and Progenics' sNDA filing for RELISTOR to treat opioid-induced constipation

Progenics Pharmaceuticals, Inc. and Salix Pharmaceuticals, Ltd. today announced that the U.S. Food and Drug Administration (FDA) has accepted for filing a supplemental New Drug Application (sNDA) for RELISTOR Subcutaneous Injection to treat opioid-induced constipation (OIC) in patients with non-cancer pain.

30 Aug 2011

ZIOPHARM initiates ZIN ATI-001 Phase 1 clinical study in advanced melanoma

ZIOPHARM Oncology, Inc. today announced that the first patient has been dosed in a Phase 1 clinical study of ZIN ATI-001, a novel DNA-based therapeutic candidate, in patients with advanced melanoma.

30 Aug 2011

BIOTRONIK Home Monitoring reduces inappropriate shocks, improves ICD battery longevity

BIOTRONIK, a leading manufacturer of implantable cardiac devices and the pioneer of wireless remote monitoring technology, announced today the first presentation of results from the ECOST randomized controlled trial.

30 Aug 2011

DNA sequencing pioneer, two pharmaceutical researchers recognized as ACS 'Heroes of Chemistry'

Two scientists developed a new drug that helped pioneer the era of "personalized medicine" for cancer patients, an approach in which one-size-fits-all drugs yield to medicines customized to the genetic endowment of individual patients. Another scientist invented today's predominant technology for genetic sequencing, deciphering the genetic blueprint in the DNA that makes up the genes of living things.

30 Aug 2011

Stent for Life Initiative aims to support implementation of primary PCI in the ESC countries

Primary PCI is the best reperfusion therapy for patients presenting with acute ST-elevation myocardial infarction. CJ Terkelsen and co-workers used the Western Denmark Heart Registry to describe the implementation of primary PCI in Denmark.

30 Aug 2011

Smarter health care spending key, according to Harvard study

Economists take on health care spending issues in presentations before the Fed's August meeting in Jackson Hole, Wyo.

30 Aug 2011

CMR predicts increased risk of sudden cardiac death in patients with myocardial infarction

Universitätsmedizin Berlin and Universität Leiden developed a method to identify a subgroup of patients with myocardial infarction that is at increased risk for sudden cardiac death.

30 Aug 2011

Postoperative outcomes of VAD bridged patients are worse than conventional therapy

Postoperative outcomes of severe heart failure patients bridged with short-term VADs to urgent heart transplantation are significantly worse than those of patients bridged with conventional support, recent data of the Spanish National Heart Transplant Registry suggest.

30 Aug 2011

Few treatment options for growing population of drug users in Afghanistan

The New York Times examines the "growing drug addiction problem" in Afghanistan, where, in 2010, about 900,000 people, or seven percent of the adult population, were using drugs, according to the U.N. Office on Drugs and Crime.

30 Aug 2011

Study: Gender gap has not diminished in reperfusion therapy

In spite of an increased attention to gender differences in treatment of myocardial infarctions, focus on adherence to guidelines and a change in predominant therapy, the gender difference in treatment and mortality regarding the big infarctions - STEMI - has not diminished from 1998-2000 to 2004-2006. For some therapies, it has actually increased.

30 Aug 2011

Results of darexaban phase II trial in recent acute coronary syndrome presented at ESC Congress

A phase II dose-finding study has found that the new oral Factor Xa inhibitor darexaban was associated with a two to four-fold increase in bleeding when added to dual antiplatelet therapy in patients following an acute coronary syndrome.

30 Aug 2011

Remote follow-up of ICD patients seems to be a safe alternative to conventional in-office methods

Results from the EVATEL trial are the first in Europe to demonstrate potential safety and efficacy benefits from the remote follow-up of ICD patients.

30 Aug 2011

Study indicates large gap in use of proven therapies for heart attack or stroke

A global study in 17 countries led by McMaster University researchers has found too few patients are using drugs proven to give significant benefits in warding off a heart attack or stroke.

30 Aug 2011

Researchers demonstrate benefits of 8-week 'Beating Heart Problems' group programme

Researchers from the Heart Research Centre in Melbourne, Australia, have demonstrated the benefits of the 8-week 'Beating Heart Problems' group programme in a randomised controlled trial.

30 Aug 2011

UT Southwestern surgeons to perform first hand transplant in North Texas

A team of surgeons at UT Southwestern Medical Center expects to perform the first hand transplant in North Texas within a year, making the institution just the sixth hospital in the U.S. to perform the rare and intricate surgery.

30 Aug 2011

Magnetic resonance imaging may predict survival in patients with advanced rectal cancer

A new study has shown that magnetic resonance imaging (MRI) used to evaluate responses to pre-surgery (neo-adjuvant) chemotherapy or radiation may predict survival among patients with advanced rectal cancer.

30 Aug 2011

Ecstasy redesigned for use against blood cancer

The illicit drug ecstasy has been redesigned by researchers at the University of WA for use in treatment of blood cancers.

30 Aug 2011

Governor Perry attacked for choosing new medical treatment

Recently, the governor of Texas and presidential hopeful had a bad back treated by injecting some of his very own fat cells, after they had been cultured and treated in a laboratory. The innovative use of a patient’s own adult stem cells is showing great promise in many conditions, including damaged joints.

29 Aug 2011

Student researchers throughout Australia compete for annual award

Student researchers from throughout Australia will compete for state and national titles in the country’s leading competition for life science, biotechnology and bio-engineering students: the 2011 AusBiotech-GSK Student Excellence Awards. Applications are now open for the 2011 awards.

29 Aug 2011

Pfizer receives FDA approval of XALKORI for ALK-positive NSCLC

Pfizer Inc. has received FDA approval of XALKORI (crizotinib) capsules - the first and only therapy specifically for patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) that is anaplastic lymphoma kinase (ALK)-positive as detected by an FDA-approved test.

29 Aug 2011

Therapy News and Research

FDA accepts Salix and Progenics' sNDA filing for RELISTOR to treat opioid-induced constipation

ZIOPHARM initiates ZIN ATI-001 Phase 1 clinical study in advanced melanoma

BIOTRONIK Home Monitoring reduces inappropriate shocks, improves ICD battery longevity

DNA sequencing pioneer, two pharmaceutical researchers recognized as ACS 'Heroes of Chemistry'

Stent for Life Initiative aims to support implementation of primary PCI in the ESC countries

Smarter health care spending key, according to Harvard study

CMR predicts increased risk of sudden cardiac death in patients with myocardial infarction

Postoperative outcomes of VAD bridged patients are worse than conventional therapy

Few treatment options for growing population of drug users in Afghanistan

Study: Gender gap has not diminished in reperfusion therapy

Results of darexaban phase II trial in recent acute coronary syndrome presented at ESC Congress

Remote follow-up of ICD patients seems to be a safe alternative to conventional in-office methods

Study indicates large gap in use of proven therapies for heart attack or stroke

Researchers demonstrate benefits of 8-week 'Beating Heart Problems' group programme

UT Southwestern surgeons to perform first hand transplant in North Texas

Magnetic resonance imaging may predict survival in patients with advanced rectal cancer

Ecstasy redesigned for use against blood cancer

Governor Perry attacked for choosing new medical treatment

Student researchers throughout Australia compete for annual award

Pfizer receives FDA approval of XALKORI for ALK-positive NSCLC

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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