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Researchers develop model to identify tumor-fighting immune cells in lung cancer patients

Researchers at the Johns Hopkins Kimmel Cancer Center and Bloomberg~Kimmel Institute for Cancer Immunotherapy have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.

3 Feb 2025

Study reveals mechanism behind CAR molecule transfer in cancer therapy

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now discovered that CAR molecules can be transferred from the CAR-T cells to other T cells in the tumour microenvironment.

3 Feb 2025

Loneliness: Two types, two impacts, and what they mean for mental health

Loneliness isn't just one thing—it has two key forms: emotional loneliness (lacking deep connections) and social loneliness (lacking social networks). Recognizing these differences is crucial for mental health interventions and public policy.

2 Feb 2025

Immune system discovery could revolutionize treatment for chronic disease and cancer

A discovery about the mechanisms that enable the immune system to sustain long-term protection could revolutionize treatment for chronic disease and cancer.

31 Jan 2025

Pain coping skills training reduces pain and improves quality of life for dialysis patients

People undergoing hemodialysis treatment for kidney failure often experience chronic pain related to their condition, but it can be difficult to manage with opioid medication and other conventional treatments.

31 Jan 2025

Early side effects of radiation may increase long-term risk for prostate cancer patients

Men undergoing radiation therapy for prostate cancer who experience side effects early in treatment may face a higher risk of developing more serious long-term urinary and bowel health issues, according to a new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center.

31 Jan 2025

Most insurance covers IUDs. Hers cost more than $14,000.

During her annual OB-GYN visit, Callie Anderson asked about getting off the birth control pill.

31 Jan 2025

New findings could make off-the-shelf CAR T cell therapy a reality

CAR T cell therapy is one of the most promising new cancer treatments to emerge in recent years. It involves removing a patient's own immune T cells and engineering them to recognize specific targets on the surface of the cancer cell.

31 Jan 2025

Emerging antibiotics at risk of resistance before clinical use

Researchers from the HUN-REN Biological Research Centre, Szeged (Hungary), have made a concerning discovery about the future of antibiotics.

31 Jan 2025

Researchers develop T cell growth method that enhances cancer-fighting ability in melanoma model

Findings indicate that altering glucose metabolism in T cells boosts their therapeutic potential against melanoma, paving the way for improved immunotherapies.

31 Jan 2025

Duke engineers develop AI platform to target undruggable disease proteins

Biomedical engineers at Duke University have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing proteins.

31 Jan 2025

Trump’s order on gender-affirming care escalates reversal of trans rights

President Donald Trump ratcheted up his administration's reversal of transgender rights on Tuesday with an executive order that seeks to intervene in parents' medical decisions by prohibiting government-funded insurance coverage of puberty blockers or surgery for people under 19.

31 Jan 2025

Breakthrough model simulates human bone marrow function in the lab

Hidden within our bones, marrow sustains life by producing billions of blood cells daily, from oxygen-carrying red cells to immune-boosting white cells.

31 Jan 2025

Antibody therapy provides protection against severe H5N1 avian flu in monkeys

A prophylactic antibody-based immune therapy protects monkeys against severe disease caused by H5N1 avian flu, University of Pittsburgh and NIH Vaccine Research Center researchers report today in Science.

30 Jan 2025

Psilocybin promotes lasting belief change by altering neural entropy

Psilocybin significantly reduces confidence in negative self-beliefs four weeks after administration, with effects linked to unitive experiences and neural entropy, suggesting a potential pathway for long-term cognitive restructuring.

30 Jan 2025

New AI approach enhances personalized medicine in cancer care

Personalized medicine aims to tailor treatments to individual patients. Until now, this has been done using a small number of parameters to predict the course of a disease.

30 Jan 2025

Revolutionizing diabetes care with innovative targets and therapeutic options

A thorough examination of modern drugs that target particular receptors and metabolic pathways for glucose and fat metabolism is presented. Recent research has revealed innovative targets and therapeutic options.

30 Jan 2025

PROTAC technology offers hope for treating castration-resistant prostate cancer

Announcing a new publication for Acta Materia Medica journal. Prostate cancer (PrCa) is the most prevalent urogenital cancer affecting men.

30 Jan 2025

ALPK2 identified as promising new therapeutic target for treatment of heart failure

Tatsuya Yoshida, Mikito Takefuji, and Toyoaki Murohara in the Department of Cardiology, Nagoya University Graduate School of Medicine, identified an enzyme, alpha-kinase 2 (ALPK2) that is specifically expressed in the heart.

30 Jan 2025

Higher intensity walking program boosts mobility in stroke survivors

A progressively higher-intensity walking exercise program combined with standard physical therapy significantly improved the quality of life and mobility in stroke survivors, according to a preliminary study to be presented at the American Stroke Association's International Stroke Conference 2025.

30 Jan 2025