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Three-dose artesunate therapy effective in treating children with malaria

A shorter anti-malaria treatment is as effective in treating seriously ill children as the standard regimen, according to new research. Researchers have shown that three doses over two days of the drug artesunate are as effective in killing the malaria parasite in the blood as five doses over three days.

20 Dec 2011

State roundup: Financial issues threaten N.Y.'s Brookdale Hospital

On two separate occasions this year, Brookdale Hospital Medical Center - a once-venerable institution that serves some of the city's most impoverished patients - has been threatened with expulsion from public-health insurance programs after flunking multiple government safety inspections. The hospital relies heavily on Medicaid and Medicare for financial support.

20 Dec 2011

Scientists discover missing link between body's biological clock and sugar metabolism system

Scientists have discovered a missing link between the body's biological clock and sugar metabolism system, a finding that may help avoid the serious side effects of drugs used for treating asthma, allergies and arthritis.

20 Dec 2011

IRSF announces new grants for research into Rett syndrome

The International Rett Syndrome Foundation (IRSF) announced today that it is awarding over $1.5M to support 18 new grants designed to study a variety of diverse topics from basic science and disease pathology to developing treatments and outcome measures for Rett syndrome.

20 Dec 2011

CREB1 molecule activates genes linked to brain longevity

Overeating may cause brain aging while eating less turns on a molecule that helps the brain stay young.

20 Dec 2011

New UA cancer research centre to focus on personalised treatment options

A new cancer research centre established at the University of Adelaide will focus on treatment options tailored to the individual, taking into account DNA and genetic variations between people.

20 Dec 2011

EETs promote primary tumor growth and metastasis in mouse models of cancer

Drugs that enhance levels of small molecules derived naturally in the body from a major component of animal fats (small molecules known as epoxyeicosatrienoic acids [EETs]) are currently in clinical trials for the treatment of high blood pressure and diabetes.

20 Dec 2011

Gene therapy may promote growth of hair cells in inner ear

Normal hearing depends on the presence of healthy hair cells in the inner ear. Gene therapy has the potential to slow the loss of hair cells and promote the growth of hair cells that have already been damaged.

20 Dec 2011

Weight loss pill without major side effects coming soon

Scientists are on their way to develop a perfect diet pill. The drug, which switches off appetite using hormones that are created naturally in the stomach when it is full, could be the first to be effective in weight loss without side effects.

19 Dec 2011

Same sex marriage legalization improves health, reduces stress among gay men: Study

According to US researchers legalizing same-sex marriage may create a healthier environment for gay men. The number of visits by gay men to health clinics dropped significantly after same-sex unions were allowed in the state Massachusetts. This was regardless of whether the men were in a stable relationship, reported the American Journal of Public Health.

19 Dec 2011

Yissum introduces novel technology for manufacturing an anti-malaria drug in tobacco

Combating malaria is one of the eight Millennium Development Goals described in the United Nations Millennium Declaration signed by all UN members at the year 2000. A key intervention to control malaria is prompt and effective treatment with artemisinin-based combination therapies.

19 Dec 2011

Individualised approach to cancer medicine considering genetic variations

A new cancer research centre established at the University of Adelaide will focus on treatment options tailored to the individual, taking into account DNA and genetic variations between people.

19 Dec 2011

Affordable artemisinin using tobacco plants

19 Dec 2011

Lixte's LB-205 shows therapeutic potential against Gaucher disease

An article in the early edition (December 12, 2011) of the Proceedings of the National Academy of Sciences USA, reported that Lixte's investigational drug, LB-205, was shown to have therapeutic potential in a laboratory model of Gaucher disease.

19 Dec 2011

Soybean compounds can increase effectiveness of radiation treatment for lung cancer

A Wayne State University researcher has shown that compounds found in soybeans can make radiation treatment of lung cancer tumors more effective while helping to preserve normal tissue.

19 Dec 2011

SIRT1 gene appears to delay onset of HD in mouse model

Working with genetically engineered mice, Johns Hopkins researchers have discovered that a gene (SIRT1) linked to slowing the aging process in cells also appears to dramatically delay the onset of Huntington's disease (HD) and slow the progression of the relentless neurodegenerative disorder.

19 Dec 2011

Scientists devise a way to reduce side effects of lung cancer therapy

Scientists may have a way to double the efficacy and reduce the side effects of radiation therapy.

17 Dec 2011

3-year study identifies key interventions to reduce maternal, newborn, child deaths

A three-year study conducted by the WHO, Aga Khan University, and the Partnership for Maternal, Newborn & Child Health (PMNCH) "has identified key interventions to reduce maternal, newborn and child deaths," PANA/Afrique en Ligne reports.

17 Dec 2011

Research reveals role of government funding in pharmaceutical R&D

Research conducted by Columbia Business School Professor Frank Lichtenberg, Courtney C. Brown Professor of Business, Finance and Economics, Healthcare and Pharmaceutical Management Program, and Bhaven Sampat, Assistant Professor in the Department of Health Policy and Management at the Mailman School of Public Health of Columbia University, identifies the respective contributions of direct and indirect government support in research and development of new pharmaceutical drugs.

16 Dec 2011

Microvascular stamp stimulates, directs blood vessel growth on wound surface

Researchers have developed a bandage that stimulates and directs blood vessel growth on the surface of a wound. The bandage, called a "microvascular stamp," contains living cells that deliver growth factors to damaged tissues in a defined pattern. After a week, the pattern of the stamp "is written in blood vessels," the researchers report.

16 Dec 2011