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Toclizumab for juvenile rheumatoid arthritis

The arthritis drug Toclizumab could be a boon for hundreds of children suffering from severe arthritis. It has been re-launched in children after being already licensed for the treatment of adults. At least two thirds of children taking tocizilumab have been able to return to a normal life, after many were bedridden or forced into wheelchairs by the disease, the clinical studies reveal.

16 Aug 2011

Fat interferes with body's sugar sensors to trigger type 2 diabetes

Researchers from the United States have identified how a high-fat diet can trigger type 2 diabetes, in experiments on mice and human tissue. They reveal in their study published in the journal Nature Medicine that fat interferes with the body's sugar sensors. The authors add that deeper understanding of the processes involved could help them develop a cure.

15 Aug 2011

Arrythmia drug may work in stroke prevention: Study

The latest research has revealed that a new drug for treating people with an irregular heartbeat has fewer side effects than the standard treatment and is just as good at cutting the risk of stroke. Rivaroxaban, which is easier for people to take, is as effective as warfarin at preventing blood clots and thus lowering the risk of stroke for patients with atrial fibrillation say researchers.

15 Aug 2011

UH, Centerre Healthcare partner to construct new rehabilitation hospital in Beachwood

University Hospitals (UH) in Cleveland, OH, and Nashville-based Centerre Healthcare Corporation announced today a joint venture to construct a comprehensive inpatient rehabilitation hospital in Beachwood, OH.

12 Aug 2011

Soligenix second quarter revenues decrease to $406,000

Soligenix, Inc., a late-stage biopharmaceutical company, announced today its financial results for the second quarter of 2011.

12 Aug 2011

Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis

For nearly 60 years, Pyrazinamide (PZA) has been used in conjunction with other medications to treat tuberculosis (TB), but scientists did not fully understand how the drug killed TB bacteria. PZA plays a unique role in shortening the duration of current TB therapy to six months and is used frequently to treat multi-drug resistant TB.

12 Aug 2011

Renewed focus on veterans' coverage gap

From the critical moments after she suffered a gunshot wound to the head in January to her triumphant return to Congress last week for a vote on the debt-limit deal, Rep. Gabrielle Giffords owes her recovery in no small part to veterans with similar injuries.

12 Aug 2011

Allergy & Asthma Specialists, P.C. adopts Aerocrine's FENO technology

Aerocrine AB today announced that Allergy & Asthma Specialists, P.C. has adopted Aerocrine's FENO technology for airway inflammation measurement as part of its clinical standardization on a system-wide basis.

12 Aug 2011

Researchers to develop new prostate cancer therapy

Prostate cancer that has become resistant to hormone treatment and that does not respond to radiation or chemotherapy requires new methods of treatment. By attacking stem cell-like cells in prostate cancer, researchers at Lund University are working on a project to develop a new treatment option.

12 Aug 2011

Research team reports first genetic sequencing of urothelial carcinoma

In an article published online this week in Nature Genetics, a University of Colorado Cancer Center team in partnership with universities in China and Denmark reports the first genetic sequencing of urothelial (transitional) carcinoma, the most prevalent type of bladder cancer.

12 Aug 2011

CPAP withdrawal leads to return of obstructive sleep apnea

The benefits of continuous positive airway pressure machines (CPAP) for patients with obstructive sleep apnea (OSA) are quickly reversed when the therapy is withdrawn, according to Swiss research.

12 Aug 2011

G-CSF therapy does not induce chromosomal instability in healthy stem cell donors

According to a study published in Blood, the Journal of the American Society of Hematology (ASH), researchers have reported that administration of granulocyte colony-stimulating factor (G-CSF), a drug that releases stem cells from the bone marrow into the blood, is unlikely to put healthy stem cell donors at risk for later development of abnormalities involving loss or gains of chromosomes that have been linked to hematologic disorders such as myelodysplastic syndromes (MDS) and acute myeloid leukemia.

12 Aug 2011

MYCN amplification can serve as a favorable prognostic indicator for neuroblastoma

Neuroblastoma, a malignant tumor that primarily affects infants and young children, is a leading cause of death for children with cancer. When amplification of the MYCN oncogene is found in the tumor, it usually indicates an aggressive tumor with rapid progression of the disease and a poor outcome. Thus MYCN amplification has come to be used as a prognostic indicator.

12 Aug 2011

NSAIDs like ibuprofen slow the spread of breast cancers

Published online on Aug. 7, 2011, the journal Nature Medicine reports that non-steroidal anti-inflammatory drugs including ibuprofen reduce the severity of postpartum breast cancers in animal models.

12 Aug 2011

Endothelial progenitor cells may repair leaky blood-brain barrier

University of South Florida Department of Neurosurgery and Brain Repair faculty members have received a $2.6 million grant from the National Institutes of Health to investigate the potential for cells derived from human bone marrow to benefit post-stroke patients by repairing the blood-brain barrier.

12 Aug 2011

Researchers discover key reason why pyrazinamide shortens duration of TB therapy

Pyrazinamide has been used in combination with other drugs as a first-line treatment for people with tuberculosis (TB) since the 1950s, but exactly how the drug works has not been well understood.

12 Aug 2011

NPL scientists mimick the ways viruses infect human cells and deliver genetic material

Scientists at the National Physical Laboratory (NPL) have mimicked the ways viruses infect human cells and deliver their genetic material. The research hopes to apply the approach to gene therapy - a therapeutic strategy to correct defective genes such as those that cause cancer.

12 Aug 2011

Turmeric effective in tennis or golfer's elbow

A new study shows that turmeric – a common culinary spice could help in the treatment of painful tendinitis which includes the conditions known as tennis or golfer's elbow.

12 Aug 2011

New model for amyotrophic lateral sclerosis

By isolating cells from patients' spinal tissue within a few days after death, researchers funded by the National Institutes of Health have developed a new model of the paralyzing disease amyotrophic lateral sclerosis.

12 Aug 2011

Nephros submits new 510(k) application with FDA for clearance of hemodiafiltration system

Nephros, Inc., a medical device company developing and marketing filtration products for therapeutic applications, infection control, and water purification, today announced that on August 11, 2011 it filed a 510(k) application with the Food and Drug Administration (FDA) for clearance of its hemodiafiltration system.

12 Aug 2011