Acetaminophen News and Research

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The pain-reliever acetaminophen (also known as paracetomol) is one of the best-selling over-the-counter medications, used by more than 200 million Americans a year. It is sold under many brand names, including Tylenol, and is an ingredient in nearly 200 medications, both over-the-counter (such as Excedrin, Midol, NyQuil, and Sudafed) and prescription (such as Vicodin).

New evidence reassures safety of acetaminophen use during pregnancy

A rigorous systematic review of the present state of knowledge on the use of acetaminophen during pregnancy and the risk of specific neurodevelopmental disorders (NDDs), such as autism and ADHD, offers reassurance that acetaminophen does not increase the risk of NDDs.

6 Nov 2025

Lab-grown organoid offers a platform to study how liver scarring develops

As chronic liver disease becomes more widespread, researchers at Science Tokyo have developed a lab-grown organoid that replicates a regenerating liver, offering new hope for future treatments.

31 Oct 2025

Improving logical reasoning in large language models for medical use

Large language models (LLMs) can store and recall vast quantities of medical information, but their ability to process this information in rational ways remains variable.

17 Oct 2025

Low-dose radiation therapy may be a suitable option for people with painful knee osteoarthritis

A single course of low-dose radiation therapy may provide a safe and effective alternative treatment option for people with painful knee osteoarthritis according to a new randomized, placebo-controlled clinical trial.

29 Sep 2025

WHO releases statement on acetaminophen use during pregnancy and autism

The World Health Organization (WHO) emphasizes that there is currently no conclusive scientific evidence confirming a possible link between autism and use of acetaminophen (also known as paracetamol) during pregnancy.

24 Sep 2025

Trump claims ‘no downside’ to avoiding Tylenol during pregnancy. He’s wrong.

Obstetricians have long advised their pregnant patients that Tylenol is the safest option to reduce fever or pain. President Donald Trump stood before a national audience on Sept. 22 and contradicted that.

24 Sep 2025

‘Sick to my stomach’: Trump distorts facts on autism, tylenol, and vaccines, scientists say

Ann Bauer, a researcher who studies Tylenol and autism, felt queasy with anxiety in the weeks leading up to the White House's much-anticipated autism announcement.

22 Sep 2025

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Discover how real-time Raman monitoring enhances API control and quality during hot melt extrusion.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 10 Sep 2025

Single-cell transcriptomics reveals new players in liver regeneration

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes.

2 Sep 2025

How do common painkillers drive stronger E. coli resistance?

Research shows that non-antibiotic medications like ibuprofen can enhance E. coli mutations, raising concerns about antimicrobial resistance in older adults.

29 Aug 2025

Common painkillers ibuprofen and paracetamol found to fuel antibiotic resistance

Ibuprofen and paracetamol are common over-the-counter medications that many of us reach for when we're sick. But new research from the University of South Australia shows that these trusted staples are quietly fuelling one of the world's biggest health threats: antibiotic resistance.

25 Aug 2025

New molecule shows promise in treating acetaminophen-induced liver injury

Acetaminophen is one of the most common painkillers and is found in hundreds of different medications. While safe at recommended doses, acetaminophen overdose is the leading cause of acute liver injury in the U.S.

18 Aug 2025

Prenatal acetaminophen linked to higher risk of autism and ADHD

Researchers at the Icahn School of Medicine at Mount Sinai have found that prenatal exposure to acetaminophen may increase the risk of neurodevelopmental disorders, including autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD), in children.

14 Aug 2025

ANXA2 positive hepatocytes drive migration based repair in acute liver failure

Acute liver failure (ALF) represents a life-threatening condition marked by rapid deterioration of liver function, often necessitating urgent liver transplantation.

18 Jul 2025

Study reveals how acetaminophen may actually relieve pain

A new study from Indiana University scientists may aid the pharmaceutical industry in better understanding a popular over-the-counter pain reliever: Tylenol.

16 May 2025

Mature liver cells trigger regeneration in response to neighboring injury

Acetaminophen is the most frequently taken fever and pain medication worldwide, but overdosing can be toxic to liver cells. In the United States, about 1,600 cases of acute liver failure and 500 deaths occur each year due to acetaminophen overuse and liver failure.

8 May 2025

Macrophages take center stage in liver healing after injury

The liver is famous for its remarkable ability to regenerate, but that healing power depends heavily on the actions of its resident immune cells. A new study spotlights macrophages, the liver's cleanup and repair specialists, revealing that these cells quickly adapt after injury to clear debris and support tissue recovery.

7 May 2025