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Kallistatin expression increases after weight loss, study reveals

After weight loss, people with overweight and obesity express more of the protein Kallistatin* in subcutaneous white adipose tissue.

18 Mar 2024

Mapping the Microbiome: Dr. Abidemi Junaid on the Groundbreaking Vagina Chip

An interview with Abidemi from at the Wyss Institute.

From Society for Laboratory Automation and Screening (SLAS) 18 Mar 2024

Unraveling the complexities of muscle repair in diabetes: A call for targeted research and therapies

Review outlines the impact of diabetes on skeletal muscle regeneration, highlighting the need for focused research and innovative therapies to tackle this growing health issue.

17 Mar 2024

Maternal obesity linked to liver cancer risk in offspring

Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major public health concern.

12 Mar 2024

Diabetes drug dulaglutide may reduce symptoms of depression

The current study highlighted the antidepressant effects of dulaglutide using the CMS depression model. Notably, the potential metabolisms that underlie the antidepressant effect of dulaglutide have been elucidated in this study.

8 Mar 2024

Biocompatible, bioresorbable sticker detects anastomotic leaks

Researchers led by Northwestern University and Washington University School of Medicine in St. Louis have developed a new, first-of-its-kind sticker that enables clinicians to monitor the health of patients' organs and deep tissues with a simple ultrasound device.

7 Mar 2024

Study reveals nerve changes linked to pain and urinary frequency in recurrent UTI sufferers

How sensory nerve sprouting and mast cell activity, driven by nerve growth factor (NGF), contribute to persistent bladder pain and dysfunction in recurrent urinary tract infection (rUTI) cases.

7 Mar 2024

Scientists design breakthrough drug to combat deadly pancreatic cancer mutation

Scientists discover a new way to disarm a deadly protein that also appears in cancers of the lung, breast and colon.

5 Mar 2024

UCSF scientists discover less invasive prenatal treatment for Angelman syndrome

In a discovery that opens the door to a less invasive way of treating some serious disorders before birth, UC San Francisco scientists have found that delivering medicine through amniotic fluid is as effective as delivering it to the fetal brain via cerebrospinal fluid.

4 Mar 2024

Study demonstrates the deleterious effects of chronic cocaine use on functional brain networks

A collaborative research endeavor by scientists in the Departments of Radiology, Neurology, and Psychology and Neuroscience at the UNC School of Medicine have demonstrated the deleterious effects of chronic cocaine use on the functional networks in the brain.

28 Feb 2024

Machine learning unveils key molecular players and immune signatures in stress cardiomyopathy

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Stress cardiomyopathy (SCM) is a reversible, self-limiting condition that manifests as left ventricular insufficiency.

28 Feb 2024

UMass Amherst study targets aplastic anemia with cell retraining approach

Researchers at the University of Massachusetts Amherst recently released a first-of-its-kind study that focuses on the rare autoimmune disorder aplastic anemia to understand how a subset of cells might be trained to correct the overzealous immune response that can lead to fatal autoimmune disorders.

27 Feb 2024

UMSOM wins $3.5 million BARDA contract to develop animals models for radiation research

University of Maryland School of Medicine Dean Mark T. Gladwin, MD, announced today that UMSOM faculty scientists have been selected as key contractors by the Biomedical Advanced Research and Development Authority (BARDA), for the federal agency's Radiation Nuclear Animal Model Development program.

26 Feb 2024

Collaborative project gets $20 million to develop new radiopharmaceutical cancer therapies

UT Health Science Center researchers Gabor Tigyi, MD, PhD, Harriet Van Vleet Endowment Professor in Basic Oncology Research, Junming Yue, PhD, associate professor in the Department of Pathology, Sue Chin Lee, PhD, in the Department of Physiology, and David Schwartz, MD, chair of the Department of Radiation Oncology, are part of a scientific leadership group awarded $20 million from the University of Tennessee-Oak Ridge Innovation Institute in partnership with Oak Ridge National Laboratory and the University of Tennessee, Knoxville, to develop new radiopharmaceutical therapies to treat cancer.

21 Feb 2024

Study links ultra-processed food consumption with higher cardiovascular risk

Systematic review and meta-analysis revealed a linear relationship between the consumption of ultra-processed foods and an increased risk of cardiovascular events, emphasizing the need for public health initiatives to mitigate this risk.

21 Feb 2024

Unlocking sulfasalazine's mechanism of action in IBD-SpA patients

Although it is one of the oldest medications used to treat patients with inflammatory bowel disease (IBD) and an effective treatment for an associated arthritis condition called spondyloarthritis (SpA), sulfasalazine's mechanism of action has been unclear.

20 Feb 2024